- Von-willebrand factor influences blood brain barrier permeability and brain inflammation in experimental allergic encephalomyelitis
[作者：Noubade, R; del Rio, R; McElvany, B; Zachary, JF; Millward, JM; Wagner, DD; Offner, H; Blankenhorn, EP; Teuscher, C,期刊：American Journal of Pathology, 页码：892-900 , 文章类型： Article，,卷期：2008年173-3]
- Weibel-Palade bodies within endothelial cells are secretory granules known to release von Witlebrand Factor (VWF), P-selectin, chemokines, and other stored molecules following histamine exposure. Mice with a disrupted VW...
- Bone marrow cell transfer into fetal circulation can ameliorate genetic skin diseases by providing fibroblasts to the skin and inducing immune tolerance
[作者：Chino, T; Tamai, K; Yamazaki, T; Otsuru, S; Kikuchi, Y; Nimura, K; Endo, M; Nagai, M; Uitto, J; Kitajima, Y; Kaneda, Y,期刊：American Journal of Pathology, 页码：803-814 , 文章类型： Article，,卷期：2008年173-3]
- Recent studies have shown that skin injury recruits bone marrow-derived fibroblasts (BMDFs) to the site of injury to accelerate tissue repair. However, whether uninjured skin can recruit BMDFs to maintain skin homeostasi...
- Development and validation of human psoriatic skin equivalents
[作者：Tjabringa, G; Bergers, M; van Rens, D; de Boer, R; Lamme, E; Schalkwijk, J,期刊：American Journal of Pathology, 页码：815-823 , 文章类型： Article，,卷期：2008年173-3]
- Psoriasis is an inflammatory skin disease driven by aberrant interactions between the epithelium and the immune system. Anti-psoriatic drugs can therefore target either the keratinocytes or the immunocytes. Here we sough...
- Sex differences in autoimmune disease from a pathological perspective
[作者：Fairweather, D; Frisancho-Kiss, S; Rose, NR,期刊：American Journal of Pathology, 页码：600-609 , 文章类型： Review，,卷期：2008年173-3]
- Autoimmune diseases affect similar to 8% of the population, 78% of whom are women. The reason for the high prevalence in women is unclear. Women are known to respond to infection, vaccination, and trauma with increased a...
- Paracrine overexpression of insulin-like growth factor-1 enhances mammary tumorigenesis in vivo
[作者：de Ostrovich, KK; Lambertz, I; Colby, JKL; Tian, J; Rundhaug, JE; Johnston, D; Conti, CJ; DiGiovanni, J; Fuchs-Young, R,期刊：American Journal of Pathology, 页码：824-834 , 文章类型： Article，,卷期：2008年173-3]
- Insulin-like growth factor-1 (IGF-1) stimulates proliferation, regulates tissue development, protects against apoptosis, and promotes the malignant phenotype in the breast and other organs. Some epidemiological studies h...
- G-protein-coupled receptor GPR49 is up-regulated in basal cell carcinoma and promotes cell proliferation and tumor formation
[作者：Tanese, K; Fukuma, M; Yamada, T; Mori, T; Yoshikawa, T; Watanabe, W; Ishiko, A; Amagai, M; Nishikawa, T; Sakamoto, M,期刊：American Journal of Pathology, 页码：835-843 , 文章类型： Article，,卷期：2008年173-3]
- The significance of Hedgehog (HH) signaling in the development of basal cell carcinoma (BCC) has been established. Although several target genes of HH signaling have been described previously, their precise role in tumor...
- Neuronal apoptosis and autophagy cross talk in aging PS/APP mice, a model of Alzheimer's disease
[作者：Yang, DS; Kumar, A; Stavrides, P; Peterson, J; Peterhoff, CM; Pawlik, M; Levy, E; Cataldo, AM; Nixon, RA,期刊：American Journal of Pathology, 页码：665-681 , 文章类型： Review，,卷期：2008年173-3]
- Mechanisms of neuronal loss in Alzheimer's disease (AD) are poorly understood. Here we show that apoptosis is a major form of neuronal cell death in PS/APP mice modeling AD-like neurodegeneration. Pyknotic neurons in adu...
- An antimetastatic role for decorin in breast cancer
[作者：Goldoni, S; Seidler, DG; Heath, J; Fassan, M; Baffa, R; Thakur, ML; Owens, RT; McQuillan, DJ; Iozzo, RV,期刊：American Journal of Pathology, 页码：844-855 , 文章类型： Article，,卷期：2008年173-3]
- Decorin, a member of the small leucine-rich proteoglycan gene family, down-regulates members of the ErbB receptor tyrosine kinase family and attenuates their signaling, leading to growth inhibition. We investigated the e...
- Elevated expression of the miR-17-92 polycistron and miR-21 in hepadnavirus-associated hepatocellular carcinoma contributes to the malignant phenotype
[作者：Connolly, E; Melegari, M; Landgraf, P; Tchaikovskaya, T; Tennant, BC; Slagle, BL; Rogler, LE; Zavolan, M; Tuschl, T; Rogler, CE,期刊：American Journal of Pathology, 页码：856-864 , 文章类型： Article，,卷期：2008年173-3]
- Alterations in microRNA (miRNA) expression in both human and animal models have been linked to many forms of cancer. Such miRNAs, which act directly as repressors of gene expression, have been found to frequently reside ...
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