- NF-kappa B modulates aquaporin-2 transcription in renal collecting duct principal cells
[作者:Hasler, U; Leroy, V; Jeon, US; Bouley, R; Dimitrov, M; Kim, JA; Brown, D; Kwon, HM; Martin, PY; Feraille, E,期刊:Journal of Biological Chemistry, 页码:28095-28105 , 文章类型: Article,,卷期:2008年283-42]
- Renal tubulo-interstitial inflammation is frequently associated with polyuria and urine concentration defects. This led us to investigate the effects of the major pro-inflammatory nuclear factor kappa B (NF-kappa B) path...
- Demosponge and sea anemone fibrillar collagen diversity reveals the early emergence of A/C clades and the maintenance of the modular structure of type V/XI collagens from sponge to human
[作者:Exposito, JY; Larroux, C; Cluzel, C; Valcourt, U; Lethias, C; Degnan, BM,期刊:Journal of Biological Chemistry, 页码:28226-28235 , 文章类型: Article,,卷期:2008年283-42]
- Collagens are often considered a metazoan hallmark, with the fibril-forming fibrillar collagens present from sponges to human. From evolutionary studies, three fibrillar collagen clades (named A, B, and C) have been defi...
- In vivo manipulation of the bleomycin biosynthetic gene cluster in Streptomyces verticillus ATCC15003 revealing new insights into its biosynthetic pathway
[作者:Galm, U; Wang, LY; Wendt-Pienkowski, E; Yang, RY; Liu, W; Tao, MF; Coughlin, JM; Shen, B,期刊:Journal of Biological Chemistry, 页码:28236-28245 , 文章类型: Article,,卷期:2008年283-42]
- Bleomycin (BLM), an important clinically used antitumor compound, and its analogs are challenging to prepare by chemical synthesis. Genetic engineering of the biosynthetic pathway in the producer strain would provide an ...
- Quality control of photosystem II - Reactive oxygen species are responsible for the damage to photosystem II under moderate heat stress
[作者:Yamashita, A; Nijo, N; Pospisil, P; Morita, N; Takenaka, D; Aminaka, R; Yamamoto, Y; Yamamoto, Y,期刊:Journal of Biological Chemistry, 页码:28380-28391 , 文章类型: Article,,卷期:2008年283-42]
- Moderate heat stress (40 degrees C for 30 min) on spinach thylakoid membranes induced cleavage of the reaction center-binding D1 protein of photosystem II, aggregation of the D1 protein with the neighboring polypeptides ...
- Phosphorylation of MyoGEF on Thr-574 by Plk1 promotes MyoGEF localization to the central spindle
[作者:Asiedu, M; Wu, D; Matsumura, F; Wei, QZ,期刊:Journal of Biological Chemistry, 页码:28392-28400 , 文章类型: Article,,卷期:2008年283-42]
- We reported previously that a guanine nucleotide exchange factor, MyoGEF, localizes to the central spindle, activates RhoA, and is required for cytokinesis. In this study, we have found that Plk1 (polo-like kinase 1) can...
- Biogenesis of iron-sulfur clusters in photosystem I - HOLO-NfuA from the cyanobacterium synechococcus sp PCC 7002 rapidly and efficiently transfers [4Fe-4S] clusters to apo-PsaC in vitro
[作者:Jin, Z; Heinnickel, M; Krebs, C; Shen, G; Golbeck, JH; Bryant, DA,期刊:Journal of Biological Chemistry, 页码:28426-28435 , 文章类型: Article,,卷期:2008年283-42]
- The NfuA protein has been postulated to act as a scaffolding protein in the biogenesis of photosystem (PS) I and other iron-sulfur (Fe/S) proteins in cyanobacteria and chloroplasts. To determine the properties of NfuA, r...
- The apolipoprotein CIII enhancer regulates both extensive histone modification and Intergenic transcription of human apolipoprotien AI/CIII/AIV genes but not apolipoprotein AV
[作者:Li, YJ; Wei, YS; Fu, XH; Hao, DL; Xue, Z; Gong, H; Zhang, ZQ; Liu, DP; Liang, CC,期刊:Journal of Biological Chemistry, 页码:28436-28444 , 文章类型: Article,,卷期:2008年283-42]
- The apolipoprotein (apo) AI/CIII/AIV/AV cluster genes are expressed at different levels in the liver and intestine. The apoCIII enhancer, a common regulatory element, regulates the tissue-specific expression of apoAI, ap...
- alpha-isopropylmalate, a leucine biosynthesis intermediate in yeast, is transported by the mitochondrial oxalacetate carrier
[作者:Marobbio, CMT; Giannuzzi, G; Paradies, E; Pierri, CL; Palmieri, F,期刊:Journal of Biological Chemistry, 页码:28445-28453 , 文章类型: Article,,卷期:2008年283-42]
- In Saccharomyces cerevisiae, alpha-isopropylmalate (alpha-IPM), which is produced in mitochondria, must be exported to the cytosol where it is required for leucine biosynthesis. Recombinant and reconstituted mitochondria...
- Interactions of S100A2 and S100A6 with the tetratricopeptide repeat proteins, Hsp90/Hsp70-organizing protein and kinesin light chain
[作者:Shimamoto, S; Takata, M; Tokuda, M; Oohira, F; Tokumitsu, H; Kobayashi, R,期刊:Journal of Biological Chemistry, 页码:28246-28258 , 文章类型: Article,,卷期:2008年283-42]
- S100A2 and S100A6 interact with several target proteins in a Ca2+-regulated manner. However, the exact intracellular roles of the S100 proteins are unclear. In this study we identified Hsp70/Hsp90-organizing protein (Hop...
- ADP competes with FAD binding in putrescine oxidase
[作者:van Hellemond, EW; Mazon, H; Heck, AJ; van den Heuvel, RHH; Heuts, DPHM; Janssen, DB; Fraaije, MW,期刊:Journal of Biological Chemistry, 页码:28259-28264 , 文章类型: Article,,卷期:2008年283-42]
- Putrescine oxidase from Rhodococcus erythropolis NCIMB 11540 (PuORh) is a soluble homodimeric flavoprotein of 100 kDa, which catalyzes the oxidative deamination of putrescine and some other aliphatic amines. The initial ...
- Stress and IGF-I differentially control cell fate through mammalian target of rapamycin (mTOR) and retinoblastoma protein (pRB)
[作者:Popowski, M; Ferguson, HA; Sion, AM; Koller, E; Knudsen, E; Van den Berg, CL,期刊:Journal of Biological Chemistry, 页码:28265-28273 , 文章类型: Article,,卷期:2008年283-42]
- Significant discoveries have recently contributed to our knowledge of intracellular growth factor and nutrient signaling via mTOR (mammalian target of rapamycin). This signaling pathway is essential in cellular metabolis...
- MicroRNAs miR-186 and miR-150 down-regulate expression of the pro-apoptotic purinergic P2X(7) receptor by activation of instability sites at the 3 '-untranslated region of the gene that decrease steady-state levels of the transcript
[作者:Zhou, LY; Qi, XP; Potashkin, JA; Abdul-Karim, FW; Gorodeski, GI,期刊:Journal of Biological Chemistry, 页码:28274-28286 , 文章类型: Article,,卷期:2008年283-42]
- The P2X(7) receptor regulates cell growth through mediation of apoptosis. P2X(7) levels are lower in cancer epithelial cells than in normal cells, and previous studies showed that expression of P2X(7) was regulated post-...
- An insecticidal GroEL protein with chitin binding activity from Xenorhabdus nematophila
[作者:Joshi, MC; Sharma, A; Kant, S; Birah, A; Gupta, GP; Khan, SR; Bhatnagar, R; Banerjee, N,期刊:Journal of Biological Chemistry, 页码:28287-28296 , 文章类型: Article,,卷期:2008年283-42]
- Xenorhabdus nematophila secretes insecticidal proteins to kill its larval prey. We have isolated an similar to 58-kDa GroEL homolog, secreted in the culture medium through outer membrane vesicles. The protein was orally ...
- NMR structure of the N-terminal coiled coil domain of the Andes hantavirus nucleocapsid protein
[作者:Wang, Y; Boudreaux, DM; Estrada, DF; Egan, CW; Jeor, SC; De Guzman, RN,期刊:Journal of Biological Chemistry, 页码:28297-28304 , 文章类型: Article,,卷期:2008年283-42]
- The hantaviruses are emerging infectious viruses that in humans can cause a cardiopulmonary syndrome or a hemorrhagic fever with renal syndrome. The nucleocapsid (N) is the most abundant viral protein, and during viral a...
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