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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共73条记录   The Cotranslational Maturation Program for the Type II Membrane Glycoprotein Influenza Neuraminidase [作者：Wang, N; Glidden, EJ; Murphy, SR; Pearse, BR; Hebert, DN,期刊：Journal of Biological Chemistry, 页码：33826-33837 , 文章类型： Article，,卷期：2008年283-49] The earliest steps in nascent protein maturation greatly affect its overall efficiency. Constraints placed on maturing proteins at these early stages limit available conformations and help to direct the native maturation... A Stromal Pool of TatA Promotes Tat-dependent Protein Transport across the Thylakoid Membrane [作者：Frielingsdorf, S; Jakob, M; Klosgen, RB,期刊：Journal of Biological Chemistry, 页码：33838-33845 , 文章类型： Article，,卷期：2008年283-49] In chloroplasts and bacteria, the Tat (twin-arginine translocation) system is engaged in transporting folded passenger proteins across the thylakoid and cytoplasmic membranes, respectively. To date, three membrane protei... Fibrinogen beta-Chain Tyrosine Nitration Is a Prothrombotic Risk Factor [作者：Parastatidis, I; Thomson, L; Burke, A; Chernysh, I; Nagaswami, C; Visser, J; Stamer, S; Liebler, DC; Koliakos, G; Heijnen, HFG; FitzGerald, GA; Weisel, JW; Ischiropoulos, H,期刊：Journal of Biological Chemistry, 页码：33846-33853 , 文章类型： Article，,卷期：2008年283-49] Elevated levels of circulating fibrinogen are associated with an increased risk of atherothrombotic diseases although a causative correlation between high levels of fibrinogen and cardiovascular complications has not bee... On the Mechanism of Pore Formation by Melittin [作者：van den Bogaart, G; Guzman, JV; Mika, JT; Poolman, B,期刊：Journal of Biological Chemistry, 页码：33854-33857 , 文章类型： Article，,卷期：2008年283-49] The mechanism of pore formation of lytic peptides, such as melittin from bee venom, is thought to involve binding to the membrane surface, followed by insertion at threshold levels of bound peptide. We show that in membr... FLN29 Deficiency Reveals Its Negative Regulatory Role in the Toll-like Receptor (TLR) and Retinoic Acid-inducible Gene I (RIG-I)-like Helicase Signaling Pathway [作者：Sanada, T; Takaesu, G; Mashima, R; Yoshida, R; Kobayashi, T; Yoshimura, A,期刊：Journal of Biological Chemistry, 页码：33858-33864 , 文章类型： Article，,卷期：2008年283-49] FLN29 was identified as an interferon (IFN)-inducible gene, and it has been shown to suppress Toll-like receptor 4-mediated NF-kappa B activation by binding to TRAF6. To elucidate the physiological roles of FLN29, we gen... Single Amino Acid Change in the Yeast Vacuolar Metal Transporters Zrc1 and Cot1 Alters Their Substrate Specificity [作者：Lin, HL; Kumanovics, A; Nelson, JM; Warner, DE; Ward, DM; Kaplan, J,期刊：Journal of Biological Chemistry, 页码：33865-33873 , 文章类型： Article，,卷期：2008年283-49] Iron is an essential nutrient but in excess may damage cells by generating reactive oxygen species due to Fenton reaction or by substituting for other transition metals in essential proteins. The budding yeast Saccharomy... Na-K-Cl Cotransporter-1 in the Mechanism of Ammonia-induced Astrocyte Swelling [作者：Jayakumar, AR; Liu, ML; Moriyama, M; Ramakrishnan, R; Forbush, B; Reddy, PVB; Norenberg, MD,期刊：Journal of Biological Chemistry, 页码：33874-33882 , 文章类型： Article，,卷期：2008年283-49] Brain edema and the consequent increase in intracranial pressure and brain herniation are major complications of acute liver failure (fulminant hepatic failure) and a major cause of death in this condition. Ammonia has b... Sec61p Is Required for ERAD-L GENETIC DISSECTION OF THE TRANSLOCATION AND ERAD-L FUNCTIONS OF Sec61P USING NOVEL DERIVATIVES OF CPY [作者：Willer, M; Forte, GMA; Stirling, CJ,期刊：Journal of Biological Chemistry, 页码：33883-33888 , 文章类型： Article，,卷期：2008年283-49] Misfolded proteins in the endoplasmic reticulum (ER) are exported to the cytosol for degradation by the proteasome in a process known as ER-associated degradation (ERAD). CPY* is a well characterized ERAD substrate whose... On the pH Regulation of Plant Aquaporins [作者：Fischer, M; Kaldenhoff, R,期刊：Journal of Biological Chemistry, 页码：33889-33892 , 文章类型： Article，,卷期：2008年283-49] The majority of plants are unable to evade unfavorable conditions such as flooding, salinity, or drought. Therefore, a fine-tuned water homeostasis appears to be of crucial importance for plant survival, and it was assum... Hepatitis C Virus NS5B Polymerase Exhibits Distinct Nucleotide Requirements for Initiation and Elongation [作者：Ferrari, E; He, ZQ; Palermo, RE; Huang, HC,期刊：Journal of Biological Chemistry, 页码：33893-33901 , 文章类型： Article，,卷期：2008年283-49] The hepatitis C virus (HCV) NS5B protein is an RNA-dependent RNA polymerase (RdRp) essential for replication of the viral RNA genome. Purified NS5B has been reported to exhibit multiple activities in vitro. Using a synth... AMP-activated Protein Kinase Activation Increases Phosphorylation of Glycogen Synthase Kinase 3 beta and Thereby Reduces cAMP-responsive Element Transcriptional Activity and Phosphoenolpyruvate Carboxykinase C Gene Expression in the Liver [作者：Horike, N; Sakoda, H; Kushiyama, A; Ono, H; Fujishiro, M; Kamata, H; Nishiyama, K; Uchijima, Y; Kurihara, Y; Kurihara, H; Asano, T,期刊：Journal of Biological Chemistry, 页码：33902-33910 , 文章类型： Article，,卷期：2008年283-49] AMP-activated protein kinase (AMPK) activation reportedly suppresses transcriptional activity of the cAMP-responsive element (CRE) in the phosphoenolpyruvate carboxykinase C (PEPCK-C) promoter and reduces hepatic PEPCK-C... Post-transcriptional Modulation of Iron Homeostasis during p53-dependent Growth Arrest [作者：Zhang, F; Wang, W; Tsuji, Y; Torti, SV; Torti, FM,期刊：Journal of Biological Chemistry, 页码：33911-33918 , 文章类型： Article，,卷期：2008年283-49] Iron plays an essential role in cell proliferation and is a required cofactor for a number of critical cellular enzymes. In this report we investigate changes in proteins of iron metabolism during p53-mediated replicativ... TSG-6 Transfers Proteins between Glycosaminoglycans via a Ser(28)-mediated Covalent Catalytic Mechanism [作者：Sanggaard, KW; Sonne-Schmidt, CS; Krogager, TP; Kristensen, T; Wisniewski, HG; Thogersen, IB; Enghild, JJ,期刊：Journal of Biological Chemistry, 页码：33919-33926 , 文章类型： Article，,卷期：2008年283-49] Studies of the interaction between Bikunin proteins, tumor necrosis factor-stimulated gene-6 protein (TSG-6), and glycos-aminoglycans have revealed a unique catalytic activity where TSG-6/heavy chain 2 transfer heavy cha... Tissue Processing of Nitrite in Hypoxia AN INTRICATE INTERPLAY OF NITRIC OXIDE-GENERATING AND-SCAVENGING SYSTEMS [作者：Feelisch, M; Fernandez, BO; Bryan, NS; Garcia-Saura, MF; Bauer, S; Whitlock, DR; Ford, PC; Janero, DR; Rodriguez, J; Ashrafian, H,期刊：Journal of Biological Chemistry, 页码：33927-33934 , 文章类型： Article，,卷期：2008年283-49] Although nitrite (NO2-) and nitrate (NO3-) have been considered traditionally inert byproducts of nitric oxide (NO) metabolism, recent studies indicate that NO2- represents an important source of NO for processes ranging... O-Linked beta-N-Acetylglucosaminyltransferase Substrate Specificity Is Regulated by Myosin Phosphatase Targeting and Other Interacting Proteins [作者：Cheung, WD; Sakabe, K; Housley, MP; Dias, WB; Hart, GW,期刊：Journal of Biological Chemistry, 页码：33935-33941 , 文章类型： Article，,卷期：2008年283-49] O-GlcNAc-transferase (OGT) substrate specificity is regulated by transiently interacting proteins. To further examine the regulation of OGT, we have identified 27 putative OGT-interacting proteins through a yeast two-hyb... Specific TRPC6 Channel Activation, a Novel Approach to Stimulate Keratinocyte Differentiation [作者：Muller, M; Essin, K; Hill, K; Beschmann, H; Rubant, S; Schempp, CM; Gollasch, M; Boehncke, WH; Harteneck, C; Muller, WE; Leuner, K,期刊：Journal of Biological Chemistry, 页码：33942-33954 , 文章类型： Article，,卷期：2008年283-49] The protective epithelial barrier in our skin undergoes constant regulation, whereby the balance between differentiation and proliferation of keratinocytes plays a major role. Impaired keratinocyte differentiation and pr...