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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共75条记录   Analysis of Conformational Changes during Activation of Protein Kinase Pak2 by Amide Hydrogen/Deuterium Exchange [作者：Hsu, YH; Johnson, DA; Traugh, JA,期刊：Journal of Biological Chemistry, 页码：36397-36405 , 文章类型： Article，,卷期：2008年283-52] During apoptotic stress, protein kinase Pak2 is cleaved by caspase 3 to form a heterotetramer that is constitutively activated following autophosphorylation. The active protein kinase migrates slightly slower than the in... FTDP-17 Mutations in Tau Alter the Regulation of Microtubule Dynamics AN "ALTERNATIVE CORE" MODEL FOR NORMAL AND PATHOLOGICAL TAU ACTION [作者：Leboeuf, AC; Levy, SF; Gaylord, M; Bhattacharya, A; Singh, AK; Jordan, MA; Wilson, L; Feinstein, SC,期刊：Journal of Biological Chemistry, 页码：36406-36415 , 文章类型： Article，,卷期：2008年283-52] Mutations affecting either the structure or regulation of the microtubule-associated protein Tau cause neuronal cell death and dementia. However, the molecular mechanisms mediating these deleterious effects remain unclea... Analysis of Glucose Transporter Topology and Structural Dynamics [作者：Blodgett, DM; Graybill, C; Carruthers, A,期刊：Journal of Biological Chemistry, 页码：36416-36424 , 文章类型： Article，,卷期：2008年283-52] Homology modeling and scanning cysteine mutagenesis studies suggest that the human glucose transport protein GLUT1 and its distant bacterial homologs LacY and GlpT share similar structures. We tested this hypothesis by m... ADP-ribosylation Factor 1 Controls the Activation of the Phosphatidylinositol 3-Kinase Pathway to Regulate Epidermal Growth Factor-dependent Growth and Migration of Breast Cancer Cells [作者：Boulay, PL; Cotton, M; Melancon, P; Claing, A,期刊：Journal of Biological Chemistry, 页码：36425-36434 , 文章类型： Article，,卷期：2008年283-52] Activation of intracellular signaling pathways by growth factors is one of the major causes of cancer development and progression. Recent studies have demonstrated that monomeric G proteins of the Ras family are key regu... Bidirectional Regulation of Kainate Receptor Surface Expression in Hippocampal Neurons [作者：Martin, S; Bouschet, T; Jenkins, EL; Nishimune, A; Henley, JM,期刊：Journal of Biological Chemistry, 页码：36435-36440 , 文章类型： Article，,卷期：2008年283-52] Kainate receptors (KARs) are crucial for the regulation of both excitatory and inhibitory neurotransmission, but little is known regarding the mechanisms controlling KAR surface expression. We used super ecliptic pHluori... Reciprocal Modulation of Function between the D-1 and D-2 Dopamine Receptors and the Na+, K+-ATPase [作者：Hazelwood, LA; Free, RB; Cabrera, DM; Skinbjerg, M; Sibley, DR,期刊：Journal of Biological Chemistry, 页码：36441-36453 , 文章类型： Article，,卷期：2008年283-52] It is well documented that dopamine can increase or decrease the activity of the Na+, K+-ATPase (NKA, sodium pump) in an organ-specific fashion. This regulation can occur, at least partially, via receptor-mediated second... Mechanistic Analysis of the Amplification and Diversification Events Induced by Vav Proteins in B-lymphocytes [作者：Caloca, MJ; Zugaza, JL; Bustelo, XR,期刊：Journal of Biological Chemistry, 页码：36454-36464 , 文章类型： Article，,卷期：2008年283-52] Vav proteins participate in the assembly of a multibranched signal transduction pathway in lymphocytes, including the stimulation of the phosphatidylinositol 3-kinase/protein kinase B and the phospholipase C-gamma/Ras GD... The Histone Demethylases JMJD1A and JMJD2B Are Transcriptional Targets of Hypoxia-inducible Factor HIF [作者：Beyer, S; Kristensen, MM; Jensen, KS; Johansen, JV; Staller, P,期刊：Journal of Biological Chemistry, 页码：36542-36552 , 文章类型： Article，,卷期：2008年283-52] Posttranslational histone modifications serve to store epigenetic information and control both nucleosome assembly and recruitment of non-histone proteins. Histone methylation occurs on arginine and lysine residues and i... Loss of Androgen Receptor in Aging and Oxidative Stress through Myb Protooncoprotein-regulated Reciprocal Chromatin Dynamics of p53 and Poly(ADP-ribose) Polymerase PARP-1 [作者：Shi, LH; Ko, S; Kim, S; Echchgadda, I; Oh, TS; Song, CS; Chatterjee, B,期刊：Journal of Biological Chemistry, 页码：36474-36485 , 文章类型： Article，,卷期：2008年283-52] Poly(ADP-ribosyl)ation of transcription factors and coregulators, mediated by the poly(ADP-ribose) polymerase PARP-1, has been emerging as an important epigenetic mechanism that controls transcriptional dynamics in respo... Nonmitochondrial ATP/ADP Transporters Accept Phosphate as Third Substrate [作者：Trentmann, O; Jung, B; Neuhaus, HE; Haferkamp, I,期刊：Journal of Biological Chemistry, 页码：36486-36493 , 文章类型： Article，,卷期：2008年283-52] Chlamydiales and Rickettsiales as metabolically impaired, intracellular pathogenic bacteria essentially rely on "energy parasitism" by the help of nucleotide transporters (NTTs). Also in plant plastids NTT-type carriers ... Nonenzymatic RNA Ligation in Water [作者：Pino, S; Ciciriello, F; Costanzo, G; Di Mauro, E,期刊：Journal of Biological Chemistry, 页码：36494-36503 , 文章类型： Article，,卷期：2008年283-52] We describe the nonenzymatic ligation of RNA oligomers in water. Dimers and tetramers are formed in a time-, pH-, and temperature-dependent reaction. Ligation efficiency depends on oligonucleotide length and sequence and... Molecular Basis of the Interaction of Saccharomyces cerevisiae Eaf3 Chromo Domain with Methylated H3K36 [作者：Sun, BF; Hong, J; Zhang, P; Dong, XC; Shen, X; Lin, DH; Ding, JP,期刊：Journal of Biological Chemistry, 页码：36504-36512 , 文章类型： Article，,卷期：2008年283-52] Eaf3 is a component of both NuA4 histone acetyltransferase and Rpd3S histone deacetylase complexes in Saccharomyces cerevisiae. It is involved in the regulation of the global pattern of histone acetylation that distingui... The Ras/cAMP/Protein Kinase A Pathway Regulates Glucose-dependent Assembly of the Vacuolar (H+)-ATPase in Yeast [作者：Bond, S; Forgac, M,期刊：Journal of Biological Chemistry, 页码：36513-36521 , 文章类型： Article，,卷期：2008年283-52] Vacuolar (H+)-ATPases (V-ATPases) are ubiquitous, ATP-driven proton pumps that acidify organelles or the extracellular space. A rapid and effective mechanism for regulating V-ATPase activity involves reversible dissociat... Actin Depolymerization Factor/Cofilin Activation Regulates Actin Polymerization and Tension Development in Canine Tracheal Smooth Muscle [作者：Zhao, R; Du, LP; Huang, YL; Wu, YD; Gunst, SJ,期刊：Journal of Biological Chemistry, 页码：36522-36531 , 文章类型： Article，,卷期：2008年283-52] The contractile activation of airway smooth muscle tissues stimulates actin polymerization, and the inhibition of actin polymerization inhibits tension development. Actin-depolymerizing factor (ADF) and cofilin are membe... Characterization of Rv3868, an Essential Hypothetical Protein of the ESX-1 Secretion System in Mycobacterium tuberculosis [作者：Luthra, A; Mahmood, A; Arora, A; Ramachandran, R,期刊：Journal of Biological Chemistry, 页码：36532-36541 , 文章类型： Article，,卷期：2008年283-52] Rv3868, a conserved hypothetical protein of the ESAT-6 secretion system of Mycobacterium tuberculosis, is essential for the secretion of at least four virulence factors. Each protein chain is similar to 63 kDa and assemb... ABCA12 Maintains the Epidermal Lipid Permeability Barrier by Facilitating Formation of Ceramide Linoleic Esters [作者：Zuo, Y; Zhuang, DZ; Han, R; Isaac, G; Tobin, JJ; Mckee, M; Welti, R; Brissette, JL; Fitzgerald, ML; Freeman, MW,期刊：Journal of Biological Chemistry, 页码：36624-36635 , 文章类型： Article，,卷期：2008年283-52] Harlequin ichthyosis is a congenital scaling syndrome of the skin in which affected infants have epidermal hyperkeratosis and a defective permeability barrier. Mutations in the gene encoding a member of the ABCA transpor...