- Potentiation of chemotherapeutic drugs by energy metabolism inhibitors 2-deoxyglucose and etomoxir
[作者:Hernlund, E; Ihrlund, LS; Khan, O; Ates, YO; Linder, S; Panaretakis, T; Shoshan, MC,期刊:International Journal of Cancer, 页码:476-483 , 文章类型: Article,,卷期:2008年123-2]
- Inhibition of energy production as a strategy for potentiation of anticancer chemotherapy was investigated using 1 glycolysis inhibitor and I fatty acid P-oxidation inhibitor-2-deoxyglucose and etomoxir, respectively, bo...
- Persistent downregulation of the pancarcinoma-associated epithelial cell adhesion molecule via active intranuclear methylation
[作者:van der Gun, BTF; Wasserkort, R; Monami, A; Jeltsch, A; Rasko, T; Slaska-Kiss, K; Cortese, R; Rots, MG; de Leij, LFMH; Ruiters, MHJ; Kiss, A; Weinhold, E; McLaughlin, PMJ,期刊:International Journal of Cancer, 页码:484-489 , 文章类型: Article,,卷期:2008年123-2]
- The epithelial cell adhesion molecule (EpCAM) is expressed at high levels on the surface of most carcinoma cells. SiRNA silencing of EpCAM expression leads to reduced metastatic potential of tumor cells demonstrating its...
- miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells
[作者:Xia, L; Zhang, DX; Du, R; Pan, YL; Zhao, LN; Sun, SR; Hong, L; Liu, J; Fan, DM,期刊:International Journal of Cancer, 页码:372-379 , 文章类型: Article,,卷期:2008年123-2]
- microRNAs are endogenous small noncoding RNAs that regulate gene expression negatively at posttranscriptional level. This latest addition to the complex gene regulatory circuitry revolutionizes our way to understanding p...
- Consortium analysis of 7 candidate SNPs for ovarian cancer
[作者:Ramus, SJ; Vierkant, RA; Johnatty, SE; Pike, MC; Van Den Berg, DJ; Wu, AH; Pearce, CL; Menon, U; Gentry-Maharaj, A; Gayther, SA; DiCioccio, RA; McGuire, V; Whittemore, AS; Song, H; Easton, DF; Pharoah, PDP; Garcia-Closas, M; Chanock, S; Lissowska, J; Brinton, L; Terry, KL; Cramer, DW; Tworoger, SS; Hankinson, SE; Berchuck, A; Moorman, PG; Schildkraut, JM; Cunningham, JM; Liebow, M; Kjaer, SK; Hogdall, E; Hogdall, C; Blaakaer, J; Ness, RB; Moysich, KB; Edwards, RP; Carney, ME; Lurie, G; Goodman, ,期刊:International Journal of Cancer, 页码:380-388 , 文章类型: Article,,卷期:2008年123-2]
- The Ovarian Cancer Association Consortium selected 7 candidate single nucleotide polymorphisms (SNPs), for which there is evidence from previous studies of an association with variation in ovarian cancer or breast cancer...
- Assessment of NORE1A as a putative tumor suppressor in human neuroblastoma
[作者:Geli, J; Kogner, P; Lanner, F; Natalishvili, N; Juhlin, C; Kiss, N; Clark, GJ; Ekstrom, TJ; Farnebo, F; Larsson, C,期刊:International Journal of Cancer, 页码:389-394 , 文章类型: Article,,卷期:2008年123-2]
- The putative tumor suppressor NORE1A (RASSF5) is a member of the Ras association domain family and is commonly inactivated in human cancer. The closely related gene family member and functional collaborator RASSF1A is a ...
- Low CAIX expression and absence of VHL gene mutation are associated with tumor aggressiveness and poor survival of clear cell renal cell carcinoma
[作者:Patard, JJ; Fergelot, P; Karakiewicz, PI; Klatte, T; Trinh, QD; Rioux-Leclercq, N; Said, JW; Belldegrun, AS; Pantuck, AJ,期刊:International Journal of Cancer, 页码:395-400 , 文章类型: Article,,卷期:2008年123-2]
- We attempted to describe, in a series of clear cell renal cell carcinoma (RCC), the relationship between CAIX expression, VHL gene mutations, tumor characteristics and outcome. Radical nephrectomy was performed in 100 pa...
- Characterization of a novel epigenetically-silenced, growth-suppressive gene, ADAMTS9, and its association with lymph node metastases in nasopharyngeal carcinoma
[作者:Lung, HL; Lo, PHY; Xie, D; Apte, SS; Cheung, AKL; Cheng, Y; Law, EWL; Chua, D; Zeng, YX; Tsao, SW; Stanbridge, EJ; Lung, ML,期刊:International Journal of Cancer, 页码:401-408 , 文章类型: Article,,卷期:2008年123-2]
- By using a functional complementation approach, suppression of tumorigenicity was observed after transfer of intact or truncated copies of chromosome 3 into a nasopharyngeal carcinoma (NPC) HONE1 cell line. The extra exo...
- REG1A expression is a prognostic marker in colorectal cancer and associated with peritoneal carcinomatosis
[作者:Astrosini, C; Roeefzaad, C; Dai, YY; Dieckgraefe, BK; Jons, T; Kemmner, W,期刊:International Journal of Cancer, 页码:409-413 , 文章类型: Article,,卷期:2008年123-2]
- By expression profiling of early staged colon carcinomas, we found regenerating islet-derived 1 alpha (REG1A) to be upregulated in patients with an unfavorable clinical outcome. For validation, REGIA expression was quant...
- Variation in the prevalence of gastric cancer in Peru
[作者:Mendoza, D; Herrera, P; Gilman, RH; Lanfranco, J; Tapia, M; Bussalleu, A; Tenorio, JHM; Guillen-Rodriguez, CE; Arrospide, MT; Piscoya, A; Rosas-Aguirre, A; Watanabe-Yamamoto, J; Ferrufino, JC; Scavino, Y; Ramirez-Ramos, A,期刊:International Journal of Cancer, 页码:414-420 , 文章类型: Article,,卷期:2008年123-2]
- Most cases of gastric cancers occur in non-industrialized countries but there is scarce information about the epidemiology of this illness in these countries. Our study examined whether there was a variation in the preva...
- Recent trends in prostate cancer mortality show a continuous decrease in several countries
[作者:Bouchardy, C; Fioretta, G; Rapiti, E; Verkooijen, HM; Rapin, CH; Schmidlin, F; Miralbell, R; Zanetti, R,期刊:International Journal of Cancer, 页码:421-429 , 文章类型: Article,,卷期:2008年123-2]
- Prostate specific antigen (PSA) screening was introduced to detect prostate cancer at an early stage and to reduce prostate cancer-specific mortality. Until results from clinical trials are available, the efficacy of PSA...
- Investigating Black-White differences in prostate cancer prognosis: A systematic review and meta-analysis
[作者:Evans, S; Metcalfe, C; Ibrahim, F; Persad, R; Ben-Shlomo, Y,期刊:International Journal of Cancer, 页码:430-435 , 文章类型: Article,,卷期:2008年123-2]
- The case-fatality rate following a diagnosis of prostate cancer is higher for Black men compared to White men. How this elevated rate arises is uncertain, with differences in disease biology, presentation, treatment and ...
- Fetal growth and the risk of childhood CNS tumors and lymphomas in Western Australia
[作者:Milne, E; Laurvick, CL; Blair, E; de Klerk, N; Charles, AK; Bower, C,期刊:International Journal of Cancer, 页码:436-443 , 文章类型: Article,,卷期:2008年123-2]
- The etiology of childhood cancers is largely unknown, although the early age at diagnosis has led to particular interest in in utero and perinatal factors. Birth weight is the most frequently studied perinatal factor in ...
- The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome
[作者:Watson, P; Vasen, HFA; Mecklin, JP; Bernstein, I; Aarnio, M; Jarvinen, HJ; Myrhoj, T; Sunde, L; Wijnen, JT; Lynch, HT,期刊:International Journal of Cancer, 页码:444-449 , 文章类型: Article,,卷期:2008年123-2]
- Persons with the Lynch syndrome (LS) are at high risk for cancer, including cancers of the small bowel, stomach, upper urologic tract (renal pelvis and ureter), ovary, biliary tract and brain tumors, in addition to the m...
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