- Suppression of integrin alpha upsilon beta 6 by RNA interference in colon cancer cells inhibits extracellular matrix degradation through the MAPK pathway
[作者:Wang, JY; Zhang, ZY; Xu, KS; Sun, XH; Yang, GY; Niu, WB; Liu, EY; Peng, C; Lin, PF; Wang, J; Chen, R; Agrez, M; Niu, J,期刊:International Journal of Cancer, 页码:1311-1317 , 文章类型: Article,,卷期:2008年123-6]
Integrin alpha upsilon beta 6 plays a very important role in the progression of colon cancer cells and is now defined as a novel, independent prognostic indicator for aggressive colon cancer in humans. Herein, we use ...
- Expression and function of fatty acid amide hydrolase in prostate cancer
[作者:Endsley, MP; Thill, R; Choudhry, I; Williams, CL; Kajdacsy-Balla, A; Campbell, WB; Nithipatikom, K,期刊:International Journal of Cancer, 页码:1318-1326 , 文章类型: Article,,卷期:2008年123-6]
- The hydrolysis of endocannabinoids has profound effects on the function of the endocannabinoid signaling system in the regulation of prostate carcinoma cells. Prostate carcinoma cells exhibit a wide range of hydrolysis a...
- Identification of new genes associated with breast cancer progression by gene expression analysis of predefined sets of neoplastic tissues
[作者:Cimino, D; Fuso, L; Sfiligoi, C; Biglia, N; Ponzone, R; Maggiorotto, F; Russo, G; Cicatiello, L; Weisz, A; Taverna, D; Sismondi, P; De Bortoli, M,期刊:International Journal of Cancer, 页码:1327-1338 , 文章类型: Article,,卷期:2008年123-6]
- Gene expression profiles were studied by microarray analysis in 2 sets of archival breast cancer tissues from patients with distinct clinical outcome. Seventy-seven differentially expressed genes were identified when com...
- IGF1 is a modifier of disease risk in hereditary non-polyposis colorectal cancer
[作者:Reeves, SG; Rich, D; Meldrum, CJ; Colyvas, K; Kurzawski, G; Suchy, J; Lubinski, J; Scott, RJ,期刊:International Journal of Cancer, 页码:1339-1343 , 文章类型: Article,,卷期:2008年123-6]
- Patients diagnosed with HNPCC harbouring a confirmed germline mutation in DNA mismatch repair (MMR) genes have an 80% lifetime risk of developing an epithelial malignancy. There is, however, considerable variation in the...
- Prevalence of oncogenic human papillomavirus infection in an organised screening population in Finland
[作者:Leinonen, M; Kotaniemi-Talonen, L; Anttila, A; Dyba, T; Tarkkanen, J; Nieminen, P,期刊:International Journal of Cancer, 页码:1344-1349 , 文章类型: Article,,卷期:2008年123-6]
- A persistent high-risk human papillomavirus (hrHPV) infection is a necessary condition for developing a cervical intraepithelial neoplasia and cervical cancer. The viral aetiology in cervical carcinogenesis has stimulate...
- Genetic alterations of HLA-class II in ovarian cancer
[作者:Kubler, K; Arndt, PF; Wardelmann, E; Landwehr, C; Krebs, D; Kuhn, W; van der Ven, K,期刊:International Journal of Cancer, 页码:1350-1356 , 文章类型: Article,,卷期:2008年123-6]
- The immune system controls tumor formation through identification and elimination of cellular alterations. Consequently, cancer development in immune competent hosts depends on strategies to evade the immune system. Modu...
- Upregulated expression of complement inhibitory proteins on bladder cancer cells and anti-MUC1 antibody immune selection
[作者:Varela, JC; Atkinson, C; Woolson, R; Keane, TE; Tomlinson, S,期刊:International Journal of Cancer, 页码:1357-1363 , 文章类型: Article,,卷期:2008年123-6]
- Membrane complement inhibitors (CD46, CD55 and CD59) are upregulated in some human cancers indicating that they play a role in immune evasion. We investigated complement inhibitor expression in bladder cancer and examine...
- Cucurbitacin B markedly inhibits growth and rapidly affects the cytoskeleton in glioblastoma multiforme
[作者:Yin, D; Wakimoto, N; Xing, HT; Lu, DN; Huynh, T; Wang, X; Black, KL; Koeffler, HP,期刊:International Journal of Cancer, 页码:1364-1375 , 文章类型: Article,,卷期:2008年123-6]
- Glioblastoma Multiforme (GBM) is almost inevitably a fatal tumor of the brain with most individuals dying within I year of diagnosis. It is the most frequent brain tumor in adults. Dose-response studies showed that Cucur...
- Prostate-derived Ets transcription factor as a favorable prognostic marker in ovarian cancer patients
[作者:Ghadersohi, A; Odunsi, K; Zhang, SZ; Azrak, RG; Bundy, BN; Manjili, MH; Li, FZ,期刊:International Journal of Cancer, 页码:1376-1384 , 文章类型: Article,,卷期:2008年123-6]
- We have previously shown that ovarian tumors express prostate-derived Ets transcription factor (PDEF). However, the precise role of PDEF in the prognosis of ovarian cancer is unknown. In our study, we report for the firs...
- Joint effects of inflammation and androgen metabolism on prostate cancer severity
[作者:Rebbeck, TR; Rennert, H; Walker, AH; Panossian, S; Tran, T; Walker, K; Spangler, E; Patacsil-Coomes, M; Sachdeva, R; Wein, AJ; Malkowicz, SB; Zeigler-Johnson, C,期刊:International Journal of Cancer, 页码:1385-1389 , 文章类型: Article,,卷期:2008年123-6]
- Multiple pathways of prostate carcinogenesis have been proposed, including those involving androgen metabolism and inflammation. These pathways are not independent, and may act together in prostate cancer etiology: andro...
- Bidi smoking and lung cancer incidence among males in Karunagappally cohort in Kerala, India
[作者:Jayalekshmy, PA; Akiba, S; Nair, MK; Gangadharan, P; Rajan, B; Nair, RK; Sugahara, T,期刊:International Journal of Cancer, 页码:1390-1397 , 文章类型: Article,,卷期:2008年123-6]
- The association or lung cancer incidence with bidi smoking was examined using a cohort study data in Karunagappally, Kerala, India. We sought interview of all the residents in Karunagappally with the population of 385,10...
- Chronic rhinosinusitis and risk of lung cancer in the Singapore Chinese Health Study
[作者:Koh, WP; Yuan, JM; Wang, RW; Seow, A; Lee, HP; Yu, MC,期刊:International Journal of Cancer, 页码:1398-1402 , 文章类型: Article,,卷期:2008年123-6]
- Epidemiologic evidence suggests that chronic inflammatory conditions of the lung may increase lung cancer risk. These chronic conditions, such as chronic obstructive pulmonary disease and asthma, commonly coexist with ch...
- Does lowering the screening age for cervical cancer in The Netherlands make sense?
[作者:van der Aa, MA; de Kok, IMCM; Siesling, S; van Ballegooijen, M; Coebergh, JWW,期刊:International Journal of Cancer, 页码:1403-1406 , 文章类型: Article,,卷期:2008年123-6]
- Recommendations for the age to initiate cervical cancer screening should be directed towards maximum detection of early cervical cancer. However, the screening programme should do more good than harm. The aim of this ana...
- A robust ex vivo model for evaluation of induction of apoptosis by rhTRAIL in combination with proteasome inhibitor MG132 in human premalignant cervical explants
[作者:Hougardy, BMT; Reesink-Peters, N; van den Heuvel, FAJ; ten Hoor, KA; Hollema, H; de Vries, EGE; de Jong, S; van der Zee, AGJ,期刊:International Journal of Cancer, 页码:1457-1465 , 文章类型: Article,,卷期:2008年123-6]
- Development of medical therapies for high-grade cervical intraepithelial neoplasia (CIN II/III) is hampered by the lack of CIN II/III cell lines. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces ap...
- Constitutive overexpression of CDC25A in primary human mammary epithelial cells results in both defective DNA damage response and chromosomal breaks at fragile sites
[作者:Cangi, MG; Piccinin, S; Pecciarini, L; Talarico, A; Dal Cin, E; Grassi, S; Grizzo, A; Maestro, R; Doglioni, C,期刊:International Journal of Cancer, 页码:1466-1471 , 文章类型: Article,,卷期:2008年123-6]
- CDC25A phosphatase, an essential component of the cell cycle machinery, is also a key player in integrating the specific signals of checkpoint control in response to DNA damage. There are several lines of evidence that i...
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