- Genomic copy number alterations as predictive markers of systemic recurrence in breast cancer
[作者:Hwang, KT; Han, W; Cho, J; Lee, JW; Ko, E; Kim, EK; Jung, SY; Jeong, EM; Bae, JY; Kang, JJ; Yang, SJ; Kim, SW; Noh, DY,期刊:International Journal of Cancer, 页码:1807-1815 , 文章类型: Article,,卷期:2008年123-8]
- We tried to establish models that predict systemic recurrence in breast cancer by selecting marker clones with DNA copy number alterations (CNAs) using an array comparative genomic hybridization (CGH). Array CGH containi...
- Identification of a novel therapeutic target for head and neck squamous cell carcinomas: A role for the neurotensin-neurotensin receptor 1 oncogenic signaling pathway
[作者:Shimizu, S; Tsukada, J; Sugimoto, T; Kikkawa, N; Sasaki, K; Chazono, H; Hanazawa, T; Okamoto, Y; Seki, N,期刊:International Journal of Cancer, 页码:1816-1823 , 文章类型: Article,,卷期:2008年123-8]
- Distant metastasis is a major factor associated with poor prognosis in head and neck squamous cell carcinomas (HNSCC), but little is known of its molecular mechanisms. New markers that predict clinical outcome, in partic...
- Promoter methylation of the bone morphogenetic protein-6 gene in association with adult T-cell leukemia
[作者:Taniguchi, A; Nemoto, Y; Yokoyama, A; Kotani, N; Imai, S; Shuin, T; Daibata, M,期刊:International Journal of Cancer, 页码:1824-1831 , 文章类型: Article,,卷期:2008年123-8]
- Bone morphogenetic proteins (BMP), belonging to the transforming growth factor-beta superfamily, are multifunctional regulators of cell proliferation, differentiation and apoptosis in various types of malignant cells. In...
- Human papillomavirus-16 and-18 in penile carcinomas: DNA methylation, chromosomal recombination and genomic variation
[作者:Kalantari, M; Villa, LL; Calleja-Macias, IE; Bernard, HU,期刊:International Journal of Cancer, 页码:1832-1840 , 文章类型: Article,,卷期:2008年123-8]
- Penile carcinomas are frequently associated with high risk human papillomavirus (HPV) types. Because little is known about the molecular biology of this association, we investigated three properties of HPV genomes in pen...
- Differential presentation of tumor antigen-derived epitopes by MHC-class I and antigen-positive tumor cells
[作者:Held, G; Neumann, F; Sturm, C; Kaestner, L; Dauth, N; Diederik; de Bruijn, R; Renner, C; Lipp, P; Pfreundschuh, M,期刊:International Journal of Cancer, 页码:1841-1847 , 文章类型: Article,,卷期:2008年123-8]
- SSX2 is a member of the family of cancer/testis antigens. The SSX2 derived peptide SSX2(103-111) has been shown to be presented to cytotoxic T-lymphocytes (CTL) by Major-Histocompatibility (MHC) Class-I complexes after e...
- Induction of IgG antibodies to MUC1 and survival in patients with epithelial ovarian cancer
[作者:Oei, ALM; Moreno, M; Verheijen, RHM; Sweep, FCGJ; Thomas, CMG; Massuger, LFAG; von Mensdorff-Pouilly, S,期刊:International Journal of Cancer, 页码:1848-1853 , 文章类型: Article,,卷期:2008年123-8]
- We investigated whether epithelial ovarian cancer patients participating in a randomized phase III trial comparing single intraperitoneal (IP) administration of yttrium-90-labeled murine HMFG1 (Y-90-muHMFG1) plus standar...
- Thymidylate synthase genotyping is more predictive for therapy response than immunohistochemistry in patients with colon cancer
[作者:Gosens, MI; Moerland, E; Lemmens, VP; Rutten, HT; Tan-Go, I; van den Brule, AJ,期刊:International Journal of Cancer, 页码:1941-1949 , 文章类型: Article,,卷期:2008年123-8]
- Thymidylate synthase (TS) is a potentially valuable marker for therapy response since it is the molecular target of 5-fluorouracil (5-FU). TS can be analyzed at the DNA (gene polymorphisms and amplification) and protein ...
- Pancreatic cancer cell lines deficient in argininosuccinate synthetase are sensitive to arginine deprivation by arginine deiminase
[作者:Bowles, TL; Kim, R; Galante, J; Parsons, CM; Virudachalam, S; Kung, HJ; Bold, RJ,期刊:International Journal of Cancer, 页码:1950-1955 , 文章类型: Article,,卷期:2008年123-8]
- Eukaryotic cells can synthesize the non-essential amino acid arginine from aspartate and citrulline using the enzyme argininosuccinate synthetase (ASS). It has been observed that ASS is underexpressed in various types of...
- Toll-like receptor-4 is expressed in meningiomas and mediates the antiproliferative action of paclitaxel
[作者:Tichomirowa, MA; Theodoropoulou, M; Daly, AF; Yassouridis, A; Hansen, S; Lu, J; Lange, M; Goldbrunner, RH; Stalla, GK; Renner, U,期刊:International Journal of Cancer, 页码:1956-1963 , 文章类型: Article,,卷期:2008年123-8]
- Meningiomas are the second most common type of brain and CNS tumors by histology. Surgery and radiotherapy are main treatment options, but meningiomas may be impossible to adequately resect or may regrow after surgery. I...
- Small field radiotherapy of head and neck cancer patients is responsible for oxidatively damaged DNA/oxidative stress on the level of a whole organism
[作者:Roszkowski, K; Gackowski, D; Rozalski, R; Dziaman, T; Siomek, A; Guz, J; Szpila, A; Foksinski, M; Olinski, R,期刊:International Journal of Cancer, 页码:1964-1967 , 文章类型: Article,,卷期:2008年123-8]
- It is possible that oxidatively damaged DNA which arises as a result of radiotherapy may be involved in the therapeutic effect or the ionizing radiation and in the side effects. Therefore, for the first time, the broad s...
- Quantitation of circulating tumor cells in blood samples from ovarian and prostate cancer patients using tumor-specific fluorescent ligands
[作者:He, W; Kularatne, SA; Kalli, KR; Prendergast, FG; Amato, RJ; Klee, GG; Hartmann, LC; Low, PS,期刊:International Journal of Cancer, 页码:1968-1973 , 文章类型: Article,,卷期:2008年123-8]
- Quantitation of circulating tumor cells (CTCs) can provide information on the stage of a malignancy, onset of disease progression and response to therapy. In an effort to more accurately quantitate CTCs, we have synthesi...
- Opposing associations of serum n-3 and n-6 polyunsaturated fatty acids with colorectal adenoma risk: An endoscopy-based case-control study
[作者:Pot, GK; Geelen, A; van Heijningen, EMB; Siezen, CLE; van Kranen, HJ; Kampman, E,期刊:International Journal of Cancer, 页码:1974-1977 , 文章类型: Article,,卷期:2008年123-8]
- Several human and animal studies have shown that n-3 polyunsaturated fatty acids (PUFA) might be associated with a decreased risk, whereas other studies showed that n-6 PUFA may be associated with an increased risk of co...
- Socioeconomic status and childhood acute lymphocytic leukemia incidence in Sao Paulo, Brazil
[作者:Ribeiro, KB; Buffler, PA; Metayer, C,期刊:International Journal of Cancer, 页码:1907-1912 , 文章类型: Article,,卷期:2008年123-8]
- To investigate the association of childhood ALL and SES, we collected data on 507 children aged 0-14 years diagnosed with ALL between 1997 and 2002 from the population-based Cancer Registry of So Paulo, Brazil, covering ...
- Soluble Fas level and cancer mortality: Findings from a nested case-control study within a large-scale prospective study
[作者:Tamakoshi, A; Nakachi, K; Ito, Y; Lin, Y; Yagyu, K; Kikuchi, S; Watanabe, Y; Inaba, Y; Tajima, K,期刊:International Journal of Cancer, 页码:1913-1916 , 文章类型: Article,,卷期:2008年123-8]
- Soluble Fas (sFas) is known to play an important role in the development of cancers of various sites. To confirm whether or not the serum Was level can be a predictor of cancer, we conducted a nested case-control study w...
- Incidence and mortality from non-Hodgkin lymphoma in Europe: The end of an epidemic?
[作者:Bosetti, C; Levi, F; Ferlay, J; Lucchini, F; Negri, E; La Vecchia, C,期刊:International Journal of Cancer, 页码:1917-1923 , 文章类型: Article,,卷期:2008年123-8]
- Non-Hodgkin lymphomas (NHL) are among the few neoplasms whose incidence and mortality have been rising in Europe and North America over the last few decades. To update trends from NHL, we considered mortality data up to ...
- Lower urinary tract symptoms and risk of prostate cancer: The HUNT 2 Cohort, Norway
[作者:Martin, RM; Vatten, L; Gunnell, D; Romundstad, P; Nilsen, TIL,期刊:International Journal of Cancer, 页码:1924-1928 , 文章类型: Article,,卷期:2008年123-8]
- Screening for early prostate cancer is frequently employed in the routine management or men with lower urinary tract symptoms (LUTS), but the evidence-base linking LUTS with prostate cancer is limited. We assessed the as...
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