- Patients with Epstein Barr virus-positive lymphomas have decreased CD4(+) T-cell responses to the viral nuclear antigen 1
[作者:Heller, KN; Arrey, F; Steinherz, P; Portlock, C; Chadburn, A; Kelly, K; Munz, C,期刊:International Journal of Cancer, 页码:2824-2831 , 文章类型: Article,,卷期:2008年123-12]
- Epstein Barr virus (EBV) causes lymphomas in immune competent and, at increased frequencies, in immune compromised patients. In the presence of an intact immune system, EBV-associated lymphomas express in most cases only...
- Selective expression of inhibitory Fc gamma receptor by metastatic melanoma impairs tumor susceptibility to IgG-dependent cellular response
[作者:Cassard, L; Cohen-Solal, JFG; Fournier, EM; Camilleri-Broet, S; Spatz, A; Chouaib, S; Badoual, C; Varin, A; Fisson, S; Duvillard, P; Boix, C; Loncar, SM; Sastre-Garau, X; Houghton, AN; Avrill, MF; Gresser, I; Fridman, WH; Sautes-Fridman, C,期刊:International Journal of Cancer, 页码:2832-2839 , 文章类型: Article,,卷期:2008年123-12]
- During melanoma progression, patients develop anti-tumor immunity including the production of anti-tumor antibodies. Although the strategies developed by malignant cells to escape anti-tumor cellular immunity have been e...
- Test positivity cutoff level of a high risk human papillomavirus test could be increased in routine cervical cancer screening
[作者:Kotaniemi-Talonen, L; Malila, N; Nieminen, P; Anttila, A; Tarkkanen, J; Laurila, P; Hakama, M,期刊:International Journal of Cancer, 页码:2902-2906 , 文章类型: Article,,卷期:2008年123-12]
- We present data on test positivity, relative sensitivity, rates of detection and relative specificity for primary human papillomavirus (HPV) testing with different cutoff levels for test positivity, in comparison to conv...
- Family history and breast cancer tumour characteristics in screened women
[作者:Couto, E; Banks, E; Reeves, G; Pirie, K; Beral, V,期刊:International Journal of Cancer, 页码:2950-2954 , 文章类型: Article,,卷期:2008年123-12]
- Women with a family history of breast cancer have an increased risk of the disease. However, since they tend to experience greater surveillance for the disease, their breast cancers may be detected at an earlier stage, t...
- Prognostic relevance of SOCS3 hypermethylation in patients with glioblastoma multiforme
[作者:Martini, M; Pallini, R; Luongo, G; Cenci, T; Lucantoni, C; Larocca, LM,期刊:International Journal of Cancer, 页码:2955-2960 , 文章类型: Article,,卷期:2008年123-12]
- Alterations in the signal transduction pathways are key mechanisms in the pathogenesis of de novo glioblastoma multiforme (GBM), which are also involved in the resistance to chemo- and radiotherapy. Here, we analyzed the...
- Phosphoglycerate kinase 1-overexpressing lung cancer cells reduce cyclooxygenase 2 expression and promote anti-tumor immunity in vivo
[作者:Tang, SJ; Ho, MY; Cho, HC; Lin, YC; Sun, GH; Chi, KH; Wang, YS; Jhou, RS; Yang, W; Sun, KH,期刊:International Journal of Cancer, 页码:2840-2848 , 文章类型: Article,,卷期:2008年123-12]
- In addition to the known function in the glycolytic pathway, phosphoglycerate kinase 1 (PGK-1) promotes reduction of plasmin disulfide bonds leading to angiostatin formation and inhibition of tumor angiogenesis. In this ...
- Novel breast cancer risk alleles and endometrial cancer risk
[作者:McGrath, M; Lee, IM; Buring, J; Hunter, DJ; De Vivo, I,期刊:International Journal of Cancer, 页码:2961-2964 , 文章类型: Article,,卷期:2008年123-12]
- Genome-wide association studies have identified several novel risk alleles for breast cancer. We hypothesized that genetic variants that are associated with breast cancer, a hormone-related disease, would also be associa...
- Why do large breast cancers still present in a population offered screening?
[作者:Kricker, A; Newman, B; Gertig, DM; Goumas, C; Armes, J; Armstrong, BK,期刊:International Journal of Cancer, 页码:2907-2914 , 文章类型: Article,,卷期:2008年123-12]
- Rates of large breast cancers should decrease in a population that is offered mammography screening, but women continue to present with them. We sought ail explanation in a population-based epidemiological study of 1,459...
- mRNAs of tyrosine hydroxylase and dopa decarboxylase but not of GD2 synthase are specific for neuroblastoma minimal disease and predicts outcome for children with high-risk disease when measured at diagnosis
[作者:Trager, C; Vernby, A; Kullman, A; Ora, I; Kogner, P; Kagedal, B,期刊:International Journal of Cancer, 页码:2849-2855 , 文章类型: Article,,卷期:2008年123-12]
- Several transcripts have been claimed to be clinically valuable for detecting minimal disease in neuroblastoma, but they have not been prospectively compared in a standardized manner. Tyrosine hydroxylase (TH), dopa deca...
- Potent in vitro and in vivo antitumor activity of interleukin-4-conjugated Pseudomonas exotoxin against human biliary tract carcinoma
[作者:Ishige, K; Shoda, J; Kawamoto, T; Matsuda, S; Ueda, T; Hyodo, I; Ohkohchi, N; Puri, RK; Kawakami, K,期刊:International Journal of Cancer, 页码:2915-2922 , 文章类型: Article,,卷期:2008年123-12]
- Targeting cytotoxins or immunotoxins to tumor cell surface receptors represents a new approach for the treatment of cancers. We tested the antitumor activity of a cytotoxin (IL-4-PE) composed of an interleukin-4 (IL-4) t...
- Identification of new accessible tumor antigens in human colon cancer by ex vivo protein biotinylation and comparative mass spectrometry analysis
[作者:Conrotto, P; Roesli, C; Rybak, J; Kischel, P; Waltregny, D; Neri, D; Castronovo, V,期刊:International Journal of Cancer, 页码:2856-2864 , 文章类型: Article,,卷期:2008年123-12]
- One or the most promising new strategies for the development of efficacious cancer therapies relies on the targeted delivery of biopharmaceutical to the tumor environment by the use of selective and specific antibodies. ...
- Quantitative monitoring of cyclin D1 expression: A molecular marker for minimal residual disease monitoring and a predictor of the disease outcome in patients with mantle cell lymphoma
[作者:Brizova, H; Kalinova, M; Krskova, L; Mrhalova, M; Kodet, R,期刊:International Journal of Cancer, 页码:2865-2870 , 文章类型: Article,,卷期:2008年123-12]
- In mantle cell lymphoma (MCL), minimal residual disease (MRD) is an indicator of the disease outcome. Quantitative methods used so far do not provide a suitable molecular marker in 30-70% patients with MCL (depending on ...
- Smoking and serum CA19-9 levels according to Lewis and secretor genotypes
[作者:Kawai, S; Suzuki, K; Nishio, K; Ishida, Y; Okada, R; Goto, Y; Naito, M; Wakai, K; Ito, Y; Hamajima, N,期刊:International Journal of Cancer, 页码:2880-2884 , 文章类型: Article,,卷期:2008年123-12]
- CA19-9, a marker for cancers of biliary tract, pancreas and colorectum, is not synthesized in those with no enzyme activity genotype (le/le) of Lewis (Le) gene. No enzyme activity genotype (se/se) of secretor (Se) gene i...
- Prenatal and perinatal risk factors for neuroblastoma
[作者:Bluhm, E; McNeil, DE; Cnattingius, S; Gridley, G; El Ghormli, L; Fraumeni, JF,期刊:International Journal of Cancer, 页码:2885-2890 , 文章类型: Article,,卷期:2008年123-12]
- Neuroblastoma is a rare embryonal tumor of childhood for which risk factors are not well known. Using a nested case-control design, we investigated prenatal, perinatal and neonatal risk factors in detail by linking 245 p...
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