- FUS-CHOP Fusion Protein Expression Coupled to p53 Deficiency Induces Liposarcoma in Mouse but Not in Human Adipose-Derived Mesenchymal Stem/Stromal Cells
[作者:Rodriguez, R; Rubio, R; Gutierrez-Aranda, I; Melen, GJ; Elosua, C; Garcia-Castro, J; Menendez, P,期刊:Stem Cells, 页码:179-192 , 文章类型: Article,,卷期:2011年29-2]
- Human sarcomas have been modeled in mice by expression of specific fusion genes in mesenchymal stem cells (MSCs). However, sarcoma models based on human MSCs are still missing. We attempted to develop a model of liposarc...
- Osteoblasts Derived from Induced Pluripotent Stem Cells Form Calcified Structures in Scaffolds Both in Vitro and in Vivo
[作者:Bilousova, G; Jun, DH; King, KB; De Langhe, S; Chick, WS; Torchia, EC; Chow, KS; Klemm, DJ; Roop, DR; Majka, SM,期刊:Stem Cells, 页码:206-216 , 文章类型: Article,,卷期:2011年29-2]
- Reprogramming somatic cells into an ESC-like state, or induced pluripotent stem (iPS) cells, has emerged as a promising new venue for customized cell therapies. In this study, we performed directed differentiation to ass...
- An Endothelial Cell Niche Induces Hepatic Specification Through Dual Repression of Wnt and Notch Signaling
[作者:Han, SY; Dziedzic, N; Gadue, P; Keller, GM; Gouon-Evans, V,期刊:Stem Cells, 页码:217-228 , 文章类型: Article,,卷期:2011年29-2]
- Complex cross-talk between endoderm and the microenvironment is an absolute requirement to orchestrate hepatic specification and expansion. In the mouse, the septum transversum and cardiac mesoderm, through secreted bone...
- PRC2 Complexes with JARID2, MTF2, and esPRC2p48 in ES Cells to Modulate ES Cell Pluripotency and Somatic Cell Reprograming
[作者:Zhang, Z; Jones, A; Sun, CW; Li, C; Chang, CW; Joo, HY; Dai, QA; Mysliwiec, MR; Wu, LC; Guo, YH; Yang, W; Liu, KM; Pawlik, KM; Erdjument-Bromage, H; Tempst, P; Lee, Y; Min, JR; Townes, TM; Wang, HB,期刊:Stem Cells, 页码:229-240 , 文章类型: Article,,卷期:2011年29-2]
- Polycomb repressive complex two (PRC2) has been implicated in embryonic stem (ES) cell pluripotency; however, the mechanistic roles of this complex are unclear. It was assumed that ES cells contain PRC2 with the same sub...
- A Nonhuman Primate Model for Urinary Bladder Regeneration Using Autologous Sources of Bone Marrow-Derived Mesenchymal Stem Cells
[作者:Sharma, AK; Bury, MI; Marks, AJ; Fuller, NJ; Meisner, JW; Tapaskar, N; Halliday, LC; Matoka, DJ; Cheng, EY,期刊:Stem Cells, 页码:241-250 , 文章类型: Article,,卷期:2011年29-2]
- Animal models that have been used to examine the regenerative capacity of cell-seeded scaffolds in a urinary bladder augmentation model have ultimately translated poorly in the clinical setting. This may be due to a numb...
- Enrichment of Human ESC-Derived Multipotent Mesenchymal Stem Cells with Immunosuppressive and Anti-Inflammatory Properties Capable to Protect Against Experimental Inflammatory Bowel Disease
[作者:Sanchez, L; Gutierrez-Aranda, I; Ligero, G; Rubio, R; Munoz-Lopez, M; Garcia-Perez, JL; Ramos, V; Real, PJ; Bueno, C; Rodriguez, R; Delgado, M; Menendez, P,期刊:Stem Cells, 页码:251-262 , 文章类型: Article,,卷期:2011年29-2]
- Human ESCs provide access to the earliest stages of human development and may serve as an unlimited source of functional cells for future cell therapies. The optimization of methods directing the differentiation of human...
- Human Placenta-Derived Adherent Cells Prevent Bone loss, Stimulate Bone formation, and Suppress Growth of Multiple Myeloma in Bone
[作者:Li, X; Ling, W; Pennisi, A; Wang, YP; Khan, S; Heidaran, M; Pal, A; Zhang, XK; He, SY; Zeitlin, A; Abbot, S; Faleck, H; Hariri, R; Shaughnessy, JD; van Rhee, F; Nair, B; Barlogie, B; Epstein, J; Yaccoby, S,期刊:Stem Cells, 页码:263-273 , 文章类型: Article,,卷期:2011年29-2]
- Human placenta has emerged as a valuable source of transplantable cells of mesenchymal and hematopoietic origin for multiple cytotherapeutic purposes, including enhanced engraftment of hematopoietic stem cells, modulatio...
- Transplanted Stem Cell-Secreted Vascular Endothelial Growth Factor Effects Poststroke Recovery, Inflammation, and Vascular Repair
[作者:Horie, N; Pereira, MP; Niizuma, K; Sun, GH; Keren-Gill, H; Encarnacion, A; Shamloo, M; Hamilton, SA; Jiang, KW; Huhn, S; Palmer, TD; Bliss, TM; Steinberg, GK,期刊:Stem Cells, 页码:274-285 , 文章类型: Article,,卷期:2011年29-2]
- Cell transplantation offers a novel therapeutic strategy for stroke; however, how transplanted cells function in vivo is poorly understood. We show for the first time that after subacute transplantation into the ischemic...
- Locally Applied Vascular Endothelial Growth Factor A Increases the Osteogenic Healing Capacity of Human Adipose-Derived Stem Cells by Promoting Osteogenic and Endothelial Differentiation
[作者:Behr, B; Tang, C; Germann, G; Longaker, MT; Quarto, N,期刊:Stem Cells, 页码:286-296 , 文章类型: Article,,卷期:2011年29-2]
- Human adipose-derived stem cells (hASCs) are known for their capability to promote bone healing when applied to bone defects. For bone tissue regeneration, both sufficient angiogenesis and osteogenesis is desirable. Vasc...
- GABA(A) Receptor Signaling Induces Osmotic Swelling and Cell Cycle Activation of Neonatal Prominin(+) Precursors
[作者:Cesetti, T; Fila, T; Obernier, K; Bengtson, CP; Li, YT; Mandl, C; Holzl-Wenig, G; Ciccolini, F,期刊:Stem Cells, 页码:307-319 , 文章类型: Article,,卷期:2011年29-2]
- Signal-regulated changes in cell size affect cell division and survival and therefore are central to tissue morphogenesis and homeostasis. In this respect, GABA receptors (GABA(A)Rs) are of particular interest because al...
- Sur8/Shoc2 Involves Both Inhibition of Differentiation and Maintenance of Self-Renewal of Neural Progenitor Cells via Modulation of Extracellular Signal-Regulated Kinase Signaling
[作者:Moon, BS; Kim, HY; Kim, MY; Yang, DH; Lee, JM; Cho, KW; Jung, HS; Choi, KY,期刊:Stem Cells, 页码:320-331 , 文章类型: Article,,卷期:2011年29-2]
- Sur8/Shoc2 is a scaffold protein that regulates the Ras-extracellular signal-regulated kinase (ERK) pathway. However, the roles of Sur8 in cellular physiologies are poorly understood. In this study, Sur8 was severely rep...
- The Rho Kinase Pathway Regulates Mouse Adult Neural Precursor Cell Migration
[作者:Leong, SY; Faux, CH; Turbic, A; Dixon, KJ; Turnley, AM,期刊:Stem Cells, 页码:332-343 , 文章类型: Article,,卷期:2011年29-2]
- Adult neural precursor cells (NPCs) in the subventricular zone (SVZ) normally migrate via the rostral migratory stream (RMS) to the olfactory bulb (OB). Following neural injury, they also migrate to the site of damage. T...
|