- Seroprevalence of Antibody to Mumps Virus in the US Population, 1999-2004
[作者:Kutty, PK; Kruszon-Moran, DM; Dayan, GH; Alexander, JP; Williams, NJ; Garcia, PE; Hickman, CJ; McQuillan, GM; Bellini, WJ,期刊:Journal of Infectious Diseases, 页码:667-674 , 文章类型: Article,,卷期:2010年202-5]
- Background. In 2006, the largest mumps outbreak in the United States in 20 years occurred. To understand prior mumps seroprevalence and factors associated with the presence of antibody to mumps virus, data from the 1999-...
- A Rapid Immune Response to 2009 Influenza A(H1N1) Vaccines in Adults: A Randomized, Double-Blind, Controlled Trial
[作者:Wu, JA; Li, W; Wang, HQ; Chen, JT; Lv, M; Zhou, JC; Liang, XF; Fang, HH; Liu, Y; Liu, LY; Wang, X; Zhang, WL; Zhang, XM; Song, LF; Qiu, YZ; Li, CG; Wang, JZ; Wang, Y; Yin, WD,期刊:Journal of Infectious Diseases, 页码:675-680 , 文章类型: Article,,卷期:2010年202-5]
- A double-blind, randomized, controlled trial involving 706 adults was conducted to evaluate the immunogenicity and safety of different dosages of whole-virion or split-virion H1N1 influenza vaccines with or without alumi...
- Association of Profoundly Impaired Immune Competence in H1N1v-Infected Patients with a Severe or Fatal Clinical Course
[作者:Agrati, C; Gioia, C; Lalle, E; Cimini, E; Castilletti, C; Armignacco, O; Lauria, FN; Ferraro, F; Antonini, M; Ippolito, G; Capobianchi, MR; Martini, F,期刊:Journal of Infectious Diseases, 页码:681-689 , 文章类型: Article,,卷期:2010年202-5]
- Background. Pandemic A/H1N1v influenza is characterized by a mild clinical course. However, a small subset of patients develops a rapidly progressive course caused by primary viral pneumonia or secondary bacterial infect...
- Human Cytomegalovirus Induces Systemic Immune Activation Characterized by a Type 1 Cytokine Signature
[作者:van de Berg, PJ; Heutinck, KM; Raabe, R; Minnee, RC; La Young, S; van Donselaar-van der Pant, KA; Bemelman, FJ; van Lier, RA; ten Berge, IJ,期刊:Journal of Infectious Diseases, 页码:690-699 , 文章类型: Article,,卷期:2010年202-5]
- Mechanisms underlying the onset and perpetuation of chronic immune activation in individuals without overt infectious or autoimmune diseases are unclear. Cytomegalovirus (CMV) is a persistent virus that induces a permane...
- DNA Methylation of Hepatitis B Virus (HBV) Genome Associated with the Development of Hepatocellular Carcinoma and Occult HBV Infection
[作者:Kaur, P; Paliwal, A; Durantel, D; Hainaut, P; Scoazec, JY; Zoulim, F; Chemin, I; Herceg, Z,期刊:Journal of Infectious Diseases, 页码:700-704 , 文章类型: Article,,卷期:2010年202-5]
- Recent studies have identified the presence of methylation in the hepatitis B virus (HBV) genome and have suggested that it may be an important mechanism regulating transcription and replication of the HBV virus. However...
- AIDS Clinical Trials Group 5197: A Placebo-Controlled Trial of Immunization of HIV-1-Infected Persons with a Replication-Deficient Adenovirus Type 5 Vaccine Expressing the HIV-1 Core Protein
[作者:Schooley, RT; Spritzler, J; Wang, HY; Lederman, MM; Havlir, D; Kuritzkes, DR; Pollard, R; Battaglia, C; Robertson, M; Mehrotra, D; Casimiro, D; Cox, K; Schock, B,期刊:Journal of Infectious Diseases, 页码:705-716 , 文章类型: Article,,卷期:2010年202-5]
- Background. Human immunodeficiency virus type 1 (HIV-1)-specific cellular immunity contributes to the control of HIV-1 replication. HIV-1-infected volunteers who were receiving antiretroviral therapy were given a replica...
- Effect of CYP2B6, ABCB1, and CYP3A5 Polymorphisms on Efavirenz Pharmacokinetics and Treatment Response: An AIDS Clinical Trials Group Study
[作者:Ribaudo, HJ; Liu, HA; Schwab, M; Schaeffeler, E; Eichelbaum, M; Motsinger-Reif, AA; Ritchie, MD; Zanger, UM; Acosta, EP; Morse, GD; Gulick, RM; Robbins, GK; Clifford, D; Haas, DW,期刊:Journal of Infectious Diseases, 页码:717-722 , 文章类型: Article,,卷期:2010年202-5]
- In AIDS Clinical Trials Group protocols 384, A5095, and A5097s, we characterized relationships between 22 polymorphisms in CYP2B6, ABCB1, and CYP3A5; plasma efavirenz exposure; and/or treatment responses. A stepwise logi...
- Persistent Microbial Translocation and Immune Activation in HIV-1-Infected South Africans Receiving Combination Antiretroviral Therapy
[作者:Cassol, E; Malfeld, S; Mahasha, P; van der Merwe, S; Cassol, S; Seebregts, C; Alfano, M; Poli, G; Rossouw, T,期刊:Journal of Infectious Diseases, 页码:723-733 , 文章类型: Article,,卷期:2010年202-5]
- Background. Microbial translocation contributes to immune activation and disease progression during chronic human immunodeficiency virus type 1 (HIV-1) infection. However, its role in the African AIDS epidemic remains co...
- Effect of Acyclovir on HIV-1 Set Point among Herpes Simplex Virus Type 2-Seropositive Persons during Early HIV-1 Infection
[作者:Kim, HN; Wang, J; Hughes, J; Coombs, R; Sanchez, J; Reid, S; Delany-Moretlwe, S; Cowan, F; Fuchs, J; Eshleman, SH; Khaki, L; McMahon, MA; Siliciano, RF; Wald, A; Celum, C,期刊:Journal of Infectious Diseases, 页码:734-738 , 文章类型: Article,,卷期:2010年202-5]
- We evaluated whether acyclovir suppression during human immunodeficiency virus type 1 (HIV-1) acquisition reduces HIV-1 set point, increases CD4 cell counts, and selects reverse-transcriptase mutations among 76 HIV-1 ser...
- Protection of Rhesus Macaques from Vaginal Infection by Vaginally Delivered Maraviroc, an Inhibitor of HIV-1 Entry via the CCR5 Co-Receptor
[作者:Veazey, RS; Ketas, TJ; Dufour, J; Moroney-Rasmussen, T; Green, LC; Klasse, PJ; Moore, JP,期刊:Journal of Infectious Diseases, 页码:739-744 , 文章类型: Article,,卷期:2010年202-5]
- An effective vaginal microbicide could reduce human immunodeficiency virus type 1 (HIV-1) transmission to women. Among microbicide candidates in clinical development is Maraviroc (MVC), a small-molecule drug that binds t...
- Pharmacokinetics and Whole-Blood Bactericidal Activity against Mycobacterium tuberculosis of Single Doses of PNU-100480 in Healthy Volunteers
[作者:Wallis, RS; Jakubiec, WM; Kumar, V; Silvia, AM; Paige, D; Dimitrova, D; Li, XX; Ladutko, L; Campbell, S; Friedland, G; Mitton-Fry, M; Miller, PF,期刊:Journal of Infectious Diseases, 页码:745-751 , 文章类型: Article,,卷期:2010年202-5]
- Background. The oxazolidinone PNU-100480 is superior to linezolid against experimental murine tuberculosis. Two metabolites contribute to but do not fully account for its superiority. This study examined the safety, tole...
- Posttreatment Reactivation of Tuberculosis in Mice Caused by Mycobacterium tuberculosis Disrupted in mce1R
[作者:Cheigh, CI; Senaratne, R; Uchida, Y; Casali, N; Kendall, LV; Riley, LW,期刊:Journal of Infectious Diseases, 页码:752-759 , 文章类型: Article,,卷期:2010年202-5]
- Background. The reactivation of tuberculosis arises in persons who are latently infected and in those who have been previously treated. The mechanism of the reactivation of tuberculosis in either situation is not well un...
- Clinical Correlates of Panton-Valentine Leukocidin (PVL), PVL Isoforms, and Clonal Complex in the Staphylococcus aureus Population of Northern Australia
[作者:Tong, SYC; Lilliebridge, RA; Bishop, EJ; Cheng, AC; Holt, DC; McDonald, MI; Giffard, PM; Currie, BJ; Boutlis, CS,期刊:Journal of Infectious Diseases, 页码:760-769 , 文章类型: Article,,卷期:2010年202-5]
- Background. Regional differences in the prevalence of Panton-Valentine leukocidin (PVL) and PVL isoform-harboring strains as well as in the local population structure of Staphylococcus aureus may influence the clinical s...
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