- GP130-STAT3 regulates epithelial cell migration and is required for repair of the bronchiolar epithelium
[作者:Kida, H; Mucenski, ML; Thitoff, AR; Le Cras, TD; Park, KS; Ikegami, M; Muller, W; Whitsett, JA,期刊:American Journal of Pathology, 页码:1542-1554 , 文章类型: Article,,卷期:2008年172-6]
- Following injury, bronchiolar cells undergo rapid squamous metaplasia, followed by proliferation and re-establishment of the complex columnar epithelium that is characteristic of the normal airway. Mechanisms that regula...
- Overexpression of lymphotoxin in T cells induces fulminant thymic involution
[作者:Heikenwalder, M; Prinz, M; Zeller, N; Lang, KS; Junt, T; Rossi, S; Tumanov, A; Schmidt, H; Priller, J; Flatz, L; Rulicke, T; Macpherson, AJ; Hollander, GA; Nedospasov, SA; Aguzzi, A,期刊:American Journal of Pathology, 页码:1555-1570 , 文章类型: Article,,卷期:2008年172-6]
- Activated lymphocytes and lymphoid-tissue inducer cells express lymphotoxins (LTs), which are essential for the organogenesis and maintenance of lymphoreticular microenvironments. Here we describe that T-cell-restricted ...
- Preeclampsia-related inflammatory cytokines regulate interleukin-6 expression in human decidual cells
[作者:Lockwood, CJ; Yen, CF; Basar, M; Kayisli, UA; Martel, M; Buhimschi, I; Buhimschi, C; Huang, SJ; Krikun, G; Schatz, F,期刊:American Journal of Pathology, 页码:1571-1579 , 文章类型: Article,,卷期:2008年172-6]
- Preeclampsia, a common pregnancy disorder associated with an increase in systemic inflammation, is the leading cause of maternal and fetal morbidity and mortality throughout the world. It is associated with shallow extra...
- Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from alpha 1, 3-galactosyltransferase gene-knockout pigs in baboons
[作者:Shimizu, A; Hisashi, Y; Kuwaki, K; Tseng, YL; Dor, FJMF; Houser, SL; Robson, SC; Schuurman, HJ; Cooper, DKC; Sachs, DH; Yamada, K; Colvin, RB,期刊:American Journal of Pathology, 页码:1471-1481 , 文章类型: Article,,卷期:2008年172-6]
- Heterotopic cardiac xenotransplantation from alpha 1,3-galactosyltransferase gene-knockout (GalT-KO) swine to baboons was performed to characterize immunological reaction to the xenograft in the absence of anti-Gal antib...
- Myofilament degradation and dysfunction of human cardiomyocytes in Fabry disease
[作者:Chimenti, C; Halmdani, N; Boontje, NM; DeCobelli, F; Esposito, A; Bronzwaer, JGF; Stienen, GJM; Russo, MA; Paulus, WJ; Frustaci, A; van der Veldent, J,期刊:American Journal of Pathology, 页码:1482-1490 , 文章类型: Article,,卷期:2008年172-6]
- Early detection of myocardial dysfunction in Fabry disease (FD) cardiomyopathy suggests the contribution of myofilament structural alterations. Six males with untreated FD cardiomyopathy submitted to cardiac studies, inc...
- By homing to the kidney, activated macrophages potently exacerbate renal injury
[作者:Wang, Y; Wang, YP; Cai, Q; Zheng, GP; Lee, VWS; Zheng, D; Li, XM; Tan, TK; Harris, DCH,期刊:American Journal of Pathology, 页码:1491-1499 , 文章类型: Article,,卷期:2008年172-6]
- Macrophages are important mediators of injury in most types of human kidney diseases; however, the pathogenic importance of both macrophage number and activation status is unknown. To examine this question, severe-combin...
- L-arginine decreases inflammation and modulates the nuclear factor-kappa B/matrix metalloproteinase cascade in mdx muscle fibers
[作者:Hnia, K; Gayraud, J; Hugon, G; Ramonatxo, M; Porte, SDL; Matecki, S; Mornet, D,期刊:American Journal of Pathology, 页码:1509-1519 , 文章类型: Article,,卷期:2008年172-6]
- Duchenne muscular dystrophy (DMD) is a lethal, X-linked disorder associated with dystrophin deficiency that results in chronic inflammation, sarcolemma damage, and severe skeletal muscle degeneration. Recently, the use o...
- Neurogenesis and alterations of neural stem cells in mouse models of cerebral amyloidosis
[作者:Ermini, FV; Grathwohl, S; Radde, R; Yamaguchi, M; Staufenbiel, M; Palmer, TD; Jucker, M,期刊:American Journal of Pathology, 页码:1520-1528 , 文章类型: Article,,卷期:2008年172-6]
- The hippocampus in Alzheimer's disease is burdened with amyloid plaques and is one of the few locations where neurogenesis continues throughout adult life. To evaluate the impact of amyloid-beta deposition on neural stem...
- Endogenous hydrogen peroxide regulates glutathione redox via nuclear factor erythroid 2-related factor 2 downstream of phosphatidylinositol 3-kinase during muscle differentiation
[作者:Ding, Y; Choi, KJ; Kim, JH; Han, XZ; Piao, YJ; Jeong, JH; Choe, W; Kang, IS; Ha, JH; Forman, HJ; Lee, J; Yoon, KS; Kim, SS,期刊:American Journal of Pathology, 页码:1529-1541 , 文章类型: Article,,卷期:2008年172-6]
- We reported previously that endogenous reactive oxygen species (ROS) function as myogenic signaling molecules. it has also been determined that excess ROS induce electrophile-response element (EpRE)-driven gene expressio...
- The tuberous sclerosis complex regulates trafficking of glucose transporters and glucose uptake
[作者:Jiang, XY; Kenerson, H; Aicher, L; Miyaoka, R; Eary, J; Bissler, J; Yeung, RS,期刊:American Journal of Pathology, 页码:1748-1756 , 文章类型: Article,,卷期:2008年172-6]
- Human cancers often display an avidity for glucose, a feature that is exploited in clinical staging and response monitoring by using F-18-fluoro-deoxyglucose (FDG) positron emission tomography. Determinants of FDG accumu...
|