- Intramembrane Proteolysis of GXGD-type Aspartyl Proteases Is Slowed by a Familial Alzheimer Disease-like Mutation
[作者:Fluhrer, R; Fukumori, A; Martin, L; Grammer, G; Haug-Kroper, M; Klier, B; Winkler, E; Kremmer, E; Condron, MM; Teplow, DB; Steiner, H; Haass, C,期刊:Journal of Biological Chemistry, 页码:30121-30128 , 文章类型: Article,,卷期:2008年283-44]
- More than 150 familial Alzheimer disease (FAD)-associated missense mutations in presenilins (PS1 and PS2), the catalytic subunit of the gamma-secretase complex, cause aberrant amyloid beta-peptide (A beta) production, by...
- Regulatory Monoubiquitination of Phosphoenolpyruvate Carboxylase in Germinating Castor Oil Seeds
[作者:Uhrig, RG; She, YM; Leach, CA; Plaxton, WC,期刊:Journal of Biological Chemistry, 页码:29650-29657 , 文章类型: Article,,卷期:2008年283-44]
- Phosphoenolpyruvate carboxylase ( PEPC) is a tightly regulated enzyme situated at the core of plant C-metabolism. Although its anaplerotic role and control by allosteric effectors, reversible phosphorylation, and oligome...
- The Cytochrome c Maturation Components CcmF, CcmH, and CcmI Form a Membrane-integral Multisubunit Heme Ligation Complex
[作者:Sanders, C; Turkarslan, S; Lee, DW; Onder, O; Kranz, RG; Daldal, F,期刊:Journal of Biological Chemistry, 页码:29715-29722 , 文章类型: Article,,卷期:2008年283-44]
- Cytochrome c maturation (Ccm) is a post-translational and post-export protein modification process that involves ten (CcmABCDEFGHI and CcdA or DsbD) components in most Gram-negative bacteria. The absence of any of these ...
- Mitochondrial Biogenesis, Switching the Sorting Pathway of the Intermembrane Space Receptor Mia40
[作者:Chacinska, A; Guiard, B; Muller, JM; Schulze-Specking, A; Gabriel, K; Kutik, S; Pfanner, N,期刊:Journal of Biological Chemistry, 页码:29723-29729 , 文章类型: Article,,卷期:2008年283-44]
- Mitochondrial precursor proteins are directed into the intermembrane space via two different routes, the presequence pathway and the redox-dependent MIA pathway. The pathways were assumed to be independent and transport ...
- A Conserved Cys-loop Receptor Aspartate Residue in the M3-M4 Cytoplasmic Loop Is Required for GABA(A) Receptor Assembly
[作者:Lo, WY; Botzolakis, EJ; Tang, X; Macdonald, RL,期刊:Journal of Biological Chemistry, 页码:29740-29752 , 文章类型: Article,,卷期:2008年283-44]
- Members of the Cys-loop superfamily of ligand-gated ion channels, which mediate fast synaptic transmission in the nervous system, are assembled as heteropentamers from a large repertoire of neuronal subunits. Although se...
- Ectodomain Lysines and Suramin Block of P2X(1) Receptors
[作者:Sim, JA; Broomhead, HE; North, RA,期刊:Journal of Biological Chemistry, 页码:29841-29846 , 文章类型: Article,,卷期:2008年283-44]
- P2X(1) receptors belong to a family of cation channels gated by extracellular ATP; they are found inter alia in smooth muscle, platelets, and immune cells. Suramin has been widely used as an antagonist at P2X receptors, ...
- Structure of the Two Transmembrane Cu+ Transport Sites of the Cu+-ATPases
[作者:Gonzalez-Guerrero, M; Eren, E; Rawat, S; Stemmler, TL; Arguello, JM,期刊:Journal of Biological Chemistry, 页码:29753-29759 , 文章类型: Article,,卷期:2008年283-44]
- Cu+-ATPases drive metal efflux from the cell cytoplasm. Paramount to this function is the binding of Cu+ within the transmembrane region and its coupled translocation across the permeability barrier. Here, we describe th...
- Regulation of Interleukin-8 Gene at a Distinct Site of Its Promoter by CCAAT Enhancer-binding Protein Homologous Protein in Prostaglandin E-2-treated Human T Cells
[作者:Cucinotta, M; Visalli, M; Aguennouz, M; Valenti, A; Loddo, S; Altucci, L; Teti, D,期刊:Journal of Biological Chemistry, 页码:29760-29769 , 文章类型: Article,,卷期:2008年283-44]
- For a long period of time, the transcription factor CCAAT/enhancer-binding protein homologous protein (CHOP) has been thought to inhibit transcriptional activity for its ability to interact with CCAAT enhancer-binding pr...
- Assembly of the Yeast Cell Wall Crh1p AND Crh2p ACT AS TRANSGLYCOSYLASES IN VIVO AND IN VITRO
[作者:Cabib, E; Farkas, V; Kosik, O; Blanco, N; Arroyo, J; McPhie, P,期刊:Journal of Biological Chemistry, 页码:29859-29872 , 文章类型: Article,,卷期:2008年283-44]
- The cross-linking of polysaccharides to assemble new cell wall in fungi requires mechanisms by which a preexisting linkage is broken for each new one made, to allow for the absence of free energy sources outside the plas...
- Substrate Recognition of Nitrogenase-like Dark Operative Protochlorophyllide Oxidoreductase from Prochlorococcus marinus
[作者:Brocker, MJ; Watzlich, D; Uliczka, F; Virus, S; Saggu, M; Lendzian, F; Scheer, H; Rudiger, W; Moser, J; Jahn, D,期刊:Journal of Biological Chemistry, 页码:29873-29881 , 文章类型: Article,,卷期:2008年283-44]
- Chlorophyll and bacteriochlorophyll biosynthesis requires the two-electron reduction of protochlorophyllide a ring D by a protochlorophyllide oxidoreductase to form chlorophyllide a. A light-dependent (light-dependent Pc...
|