- Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial
[作者:Ho, TW; Ferrari, MD; Dodick, DW; Galet, V; Kost, J; Fan, XY; Leibensperger, H; Froman, S; Assaid, C; Lines, C; Koppen, H; Winner, PK,期刊:Lancet, 页码:2115-2123 , 文章类型: Article,,卷期:2008年372-9656]
- Background Calcitonin gene-related peptide (CGRP) probably has a role in migraine pathophysiology, and antagonism of its receptors might provide treatment without the vasoconstrictor effects of triptans. We aimed to asse...
- Inequalities in healthy life years in the 25 countries of the European Union in 2005: a cross-national meta-regression analysis
[作者:Jagger, C; Gillies, C; Moscone, F; Cambois, E; Van Oyen, H; Nusselder, W; Robine, JM,期刊:Lancet, 页码:2124-2131 , 文章类型: Article,,卷期:2008年372-9656]
- Background Although life expectancy in the European Union (EU) is increasing, whether most of these extra years are spent in good health is unclear. This information would be crucial to both contain health-care costs and...
- General anaesthesia versus local anaesthesia for carotid surgery (GALA): a multicentre, randomised controlled trial
[作者:Lewis, SC; Warlow, CP; Bodenham, AR; Colam, B; Rothwell, PM; Torgerson, D; Dellagrammaticas, D; Horrocks, M; Liapis, C; Banning, AP; Gough, M; Gough, MJ,期刊:Lancet, 页码:2132-2142 , 文章类型: Article,,卷期:2008年372-9656]
- Background The effect of carotid endarterectomy in lowering the risk of stroke ipsilateral to severe atherosclerotic carotid-artery stenosis is offset by complications during or soon after surgery. We compared surgery un...
- Multiple courses of antenatal corticosteroids for preterm birth (MACS): a randomised controlled trial
[作者:Murphy, KE; Hannah, ME; Willan, AR; Hewson, SA; Ohlsson, A; Kelly, EN; Matthews, SG; Saigal, S; Asztalos, E; Ross, S; Delisle, MF; Amankwah, K; Guselle, P; Gafni, A; Lee, SK; Armson, BA,期刊:Lancet, 页码:2143-2151 , 文章类型: Article,,卷期:2008年372-9656]
- Background One course of antenatal corticosteroids reduces the risk of respiratory distress syndrome and neonatal death. Weekly doses given to women who remain undelivered after a single course may have benefits (less re...
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