- The promotion of human malignant melanoma growth by mesoporous silica nanoparticles through decreased reactive oxygen species
[作者:Huang, XL; Zhuang, J; Teng, X; Li, LL; Chen, D; Yan, XY; Tang, FQ,期刊:BIOMATERIALS, 页码:6142-6153 , 文章类型: Article,,卷期:2010年31-24]
- The concept that mesoporous silica nanoparticles (MSNs) are regarded as ideal novel drug delivery carriers in tumor therapy has been introduced extensively, but the effects of MSNs on tumor growth have received little at...
- Effect of mechanical factors on the function of engineered human blood microvessels in microfluidic collagen gels
[作者:Price, GM; Wong, KHK; Truslow, JG; Leung, AD; Acharya, C; Tien, J,期刊:BIOMATERIALS, 页码:6182-6189 , 文章类型: Article,,卷期:2010年31-24]
- This work examines how mechanical signals affect the barrier function and stability of engineered human microvessels in microfluidic type I collagen gels. Constructs that were exposed to chronic low flow displayed high p...
- Effects of fractal surface on C6 glioma cell morphogenesis and differentiation in vitro
[作者:Wang, P; Li, L; Zhang, C; Lei, QF; Fang, WJ,期刊:BIOMATERIALS, 页码:6201-6206 , 文章类型: Article,,卷期:2010年31-24]
- Neurons and glial cells in the brain are surrounded by a fractal environment. A fractal alkylketene dimmer (AKD) surface was shown to provide such a biomimetic environment for glial cell culture. However, little is known...
- Urinary bladder smooth muscle regeneration utilizing bone marrow derived mesenchymal stem cell seeded elastomeric poly(1,8-octanediol-co-citrate) based thin films
[作者:Sharma, AK; Hota, PV; Matoka, DJ; Fuller, NJ; Jandali, D; Thaker, H; Ameer, GA; Cheng, EY,期刊:BIOMATERIALS, 页码:6207-6217 , 文章类型: Article,,卷期:2010年31-24]
- Bladder regeneration studies have yielded inconclusive results possibly due to the use of unfavorable cells and primitive scaffold design. We hypothesized that human mesenchymal stem cells seeded onto poly(1,8-octanediol...
- Osteogenic differentiation of human mesenchymal stem cells using RGD-modified BMP-2 coated microspheres
[作者:Park, JS; Yang, HN; Jeon, SY; Woo, DG; Na, K; Park, KH,期刊:BIOMATERIALS, 页码:6239-6248 , 文章类型: Article,,卷期:2010年31-24]
- Micro-structured scaffolds formed with poly(lactic- co -glycolic acid) (PLGA) microspheres were composed of adhesion molecules and growth factors. PLGA microspheres, constructed with Arg-Gly-Asp (RGD) peptide and bone mo...
- Dual therapeutic action of antibiotic-loaded nanosheets for the treatment of gastrointestinal tissue defects
[作者:Fujie, T; Saito, A; Kinoshita, M; Miyazaki, H; Ohtsubo, S; Saitoh, D; Takeoka, S,期刊:BIOMATERIALS, 页码:6269-6278 , 文章类型: Article,,卷期:2010年31-24]
- An ultra-thin polymer film (nanosheet) composed of polysaccharides (i.e., polysaccharide nanosheet) provides sufficient adhesiveness, flexibility and robustness to act as an effective wound dressing. We have recently dem...
- A pH/Enzyme-responsive tumor-specific delivery system for doxorubicin
[作者:Dong, L; Xia, SH; Wu, K; Huang, Z; Chen, HA; Chen, JN; Zhang, JF,期刊:BIOMATERIALS, 页码:6309-6316 , 文章类型: Article,,卷期:2010年31-24]
- To overcome the cardiotoxicity of doxorubicin, a self-assembled pH/enzyme-responsive system was developed. Cationic gelatin combined polyGC-DOX intercalation tightly to form compact nanoscale complexes (CPX1) which then ...
- 2-Methacryloyloxyethyl phosphorylcholine polymer (MPC)-coating improves the transfection activity of GALA-modified lipid nanoparticles by assisting the cellular uptake and intracellular dissociation of plasmid DNA in primary hepatocytes
[作者:Ukawa, M; Akita, H; Masuda, T; Hayashi, Y; Konno, T; Ishihara, K; Harashima, H,期刊:BIOMATERIALS, 页码:6355-6362 , 文章类型: Article,,卷期:2010年31-24]
- We previously reported that modification of GALA peptide on the surface of liposomes enhanced fusion with endosomal membrane, and cytoplasmic release of encapsulated macromolecules. We report herein that an additional co...
- The dependence of MG63 osteoblast responses to (meth)acrylate-based networks on chemical structure and stiffness
[作者:Smith, KE; Hyzy, SL; Sunwoo, M; Gall, KA; Schwartz, Z; Boyan, BD,期刊:BIOMATERIALS, 页码:6131-6141 , 文章类型: Article,,卷期:2010年31-24]
- The cell response to an implant is regulated by the implant's surface properties including topography and chemistry, but less is known about how the mechanical properties affect cell behavior. The objective of this study...
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