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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共8条记录   Antisense HIF-1 alpha prevents acquired tumor resistance to angiostatin gene therapy [作者：Sun, X; Vale, M; Jiang, X; Gupta, R; Krissansen, GW,期刊：Cancer gene therapy, 页码：532-540 , 文章类型： Article，,卷期：2010年17-8] Angiostatin is a naturally occurring inhibitor of angiogenesis that is being developed as a drug to fight cancer. In this study we reveal that EL-4 tumors established in mice rapidly develop resistance to angiostatin gen... Gemcitabine synergistically enhances the effect of adenovirus gene therapy through activation of the CMV promoter in pancreatic cancer cells [作者：Onimaru, M; Ohuchida, K; Egami, T; Mizumoto, K; Nagai, E; Cui, L; Toma, H; Matsumoto, K; Hashizume, M; Tanaka, M,期刊：Cancer gene therapy, 页码：541-549 , 文章类型： Article，,卷期：2010年17-8] Adenovirus-mediated gene therapy shows remarkable promise as a new strategy for advanced pancreatic cancer, but satisfactory clinical results have not yet been obtained. To improve this gene therapy, we investigated the ... Oncolytic measles viruses encoding interferon beta and the thyroidal sodium iodide symporter gene for mesothelioma virotherapy [作者：Li, H; Peng, KW; Dingli, D; Kratzke, RA; Russell, SJ,期刊：Cancer gene therapy, 页码：550-558 , 文章类型： Article，,卷期：2010年17-8] Mesothelioma usually leads to death within 8-14 months of diagnosis. To increase the potency of oncolytic measles viruses (MVs) for mesothelioma therapy, we inserted the interferon b (IFN beta) gene alone or with the hum... Persistent expression of biologically active anti-HER2 antibody by AAVrh.10-mediated gene transfer [作者：Wang, G; Qiu, J; Wang, R; Krause, A; Boyer, JL; Hackett, NR; Crystal, RG,期刊：Cancer gene therapy, 页码：559-570 , 文章类型： Article，,卷期：2010年17-8] Trastuzumab (Herceptin) is a recombinant humanized monoclonal antibody (mAb) directed against an extracellular region of the human epidermal growth-factor receptor type 2 (HER2) protein. We hypothesized that a single ade... Bleomycin/interleukin-12 electrochemogenetherapy for treating naturally occurring spontaneous neoplasms in dogs [作者：Reed, SD; Fulmer, A; Buckholz, J; Zhang, B; Cutrera, J; Shiomitsu, K; Li, S,期刊：Cancer gene therapy, 页码：571-578 , 文章类型： Article，,卷期：2010年17-8] On the basis of superior outcomes from electrochemogenetherapy (ECGT) compared with electrochemotherapy in mice, we determined the efficacy of ECGT applied to spontaneous canine neoplasms. Intralesional bleomycin (BLM) a... Autophagy is induced by adenoviral-mediated interferon a treatment in interferon resistant bladder cancer and normal urothelial cells as a cell death protective mechanism but not by the bystander factors produced [作者：Zhang, XQ; Dunner, K; Benedict, WF,期刊：Cancer gene therapy, 页码：579-584 , 文章类型： Article，,卷期：2010年17-8] We have previously shown that adenoviral-mediated interferon alpha (Ad-IFN alpha) treatment is highly cytotoxic to tumor cells which are resistant to the IFN alpha protein. We now report that autophagy is produced after ... Armoring CRAds with p21/Waf-1 shRNAs: the next generation of oncolytic adenoviruses [作者：Hoti, N; Chowdhury, WH; Mustafa, S; Ribas, J; Castanares, M; Johnson, T; Liu, M; Lupold, SE; Rodriguez, R,期刊：Cancer gene therapy, 页码：585-597 , 文章类型： Article，,卷期：2010年17-8] Conditionally replicating adenoviruses (CRAds) represent a promising modality for the treatment of neoplastic diseases, including Prostate Cancer. Selectively replicating viruses can be generated by placing a tissue or c... MicroRNA and drug resistance [作者：Ma, J; Dong, C; Ji, C,期刊：Cancer gene therapy, 页码：523-531 , 文章类型： Review，,卷期：2010年17-8] Chemotherapy is the preferred treatment for malignancies. However, a successful long-term use of chemotherapy is often prevented by the development of drug resistance. Many mechanisms such as gene mutation, DNA methylati...