- The Human Papillomavirus Type 16 E5 Oncoprotein Inhibits Epidermal Growth Factor Trafficking Independently of Endosome Acidification
[作者:Suprynowicz, FA; Krawczyk, E; Hebert, JD; Sudarshan, SR; Simic, V; Kamonjoh, CM; Schlegel, R,期刊:Journal of virology, 页码:10619-10629 , 文章类型: Article,,卷期:2010年84-20]
- The human papillomavirus type 16 E5 oncoprotein (16E5) enhances acute, ligand-dependent activation of the epidermal growth factor receptor (EGFR) and concomitantly alkalinizes endosomes, presumably by binding to the 16-k...
- Genotype-Specific Neutralization and Protection by Antibodies against Dengue Virus Type 3
[作者:Brien, JD; Austin, SK; Sukupolvi-Petty, S; O'Brien, KM; Johnson, S; Fremont, DH; Diamond, MS,期刊:Journal of virology, 页码:10630-10643 , 文章类型: Article,,卷期:2010年84-20]
- Dengue viruses (DENV) comprise a family of related positive-strand RNA viruses that infect up to 100 million people annually. Currently, there is no approved vaccine or therapy to prevent infection or diminish disease se...
- MicroRNA 203 Expression in Keratinocytes Is Dependent on Regulation of p53 Levels by E6
[作者:McKenna, DJ; McDade, SS; Patel, D; McCance, DJ,期刊:Journal of virology, 页码:10644-10652 , 文章类型: Article,,卷期:2010年84-20]
- A screen of microRNA (miRNA) expression following differentiation in human foreskin keratinocytes (HFKs) identified changes in several miRNAs, including miRNA 203 (miR-203), which has previously been shown to play an imp...
- Papillomavirus Infection Requires gamma Secretase
[作者:Karanam, B; Peng, SW; Li, T; Buck, C; Day, PM; Roden, RBS,期刊:Journal of virology, 页码:10661-10670 , 文章类型: Article,,卷期:2010年84-20]
- The mechanism by which papillomaviruses breach cellular membranes to deliver their genomic cargo to the nucleus is poorly understood. Here, we show that infection by a broad range of papillomavirus types requires the int...
- Identification of Alpha Interferon-Induced Genes Associated with Antiviral Activity in Daudi Cells and Characterization of IFIT3 as a Novel Antiviral Gene
[作者:Schmeisser, H; Mejido, J; Balinsky, CA; Morrow, AN; Clark, CR; Zhao, T; Zoon, KC,期刊:Journal of virology, 页码:10671-10680 , 文章类型: Article,,卷期:2010年84-20]
- A novel assay was developed for Daudi cells in which the antiviral (AV) and antiproliferative (AP) activities of interferon (IFN) can be measured simultaneously. Using this novel assay, conditions allowing IFN AV protect...
- The African Swine Fever Virus DP71L Protein Recruits the Protein Phosphatase 1 Catalytic Subunit To Dephosphorylate eIF2 alpha and Inhibits CHOP Induction but Is Dispensable for These Activities during Virus Infection
[作者:Zhang, FQ; Moon, A; Childs, K; Goodbourn, S; Dixon, LK,期刊:Journal of virology, 页码:10681-10689 , 文章类型: Article,,卷期:2010年84-20]
- The African swine fever virus (ASFV) DP71L protein is present in all isolates as either a short form of 70 to 72 amino acids or a long form of about 184 amino acids, and both of these share sequence similarity to the C-t...
- Antibody 2G12 Recognizes Di-Mannose Equivalently in Domain- and Nondomain-Exchanged Forms but Only Binds the HIV-1 Glycan Shield if Domain Exchanged
[作者:Doores, KJ; Fulton, Z; Huber, M; Wilson, IA; Burton, DR,期刊:Journal of virology, 页码:10690-10699 , 文章类型: Article,,卷期:2010年84-20]
- The broadly neutralizing anti-human immunodeficiency virus type 1 (HIV-1) antibody 2G12 targets the high-mannose cluster on the glycan shield of HIV-1. 2G12 has a unique V-H domain-exchanged structure, with a multivalent...
- Very Few Substitutions in a Germ Line Antibody Are Required To Initiate Significant Domain Exchange
[作者:Huber, M; Le, KM; Doores, KJ; Fulton, Z; Stanfield, RL; Wilson, IA; Burton, DR,期刊:Journal of virology, 页码:10700-10707 , 文章类型: Article,,卷期:2010年84-20]
- 2G12 is a broadly neutralizing anti-HIV-1 monoclonal human IgG1 antibody reactive with a high-mannose glycan cluster on the surface of glycoprotein gp120. A key feature of this very highly mutated antibody is domain exch...
- Virulence Determinants of Avian H5N1 Influenza A Virus in Mammalian and Avian Hosts: Role of the C-Terminal ESEV Motif in the Viral NS1 Protein
[作者:Zielecki, F; Semmler, I; Kalthoff, D; Voss, D; Mauel, S; Gruber, AD; Beer, M; Wolff, T,期刊:Journal of virology, 页码:10708-10718 , 文章类型: Article,,卷期:2010年84-20]
- We assessed the prediction that access of the viral NS1 protein to cellular PDZ domain protein networks enhances the virulence of highly pathogenic avian influenza A viruses. The NS1 proteins of most avian influenza viru...
- Simian Virus 40 Activates ATR-Delta p53 Signaling To Override Cell Cycle and DNA Replication Control
[作者:Rohaly, G; Korf, K; Dehde, S; Dornreiter, I,期刊:Journal of virology, 页码:10727-10747 , 文章类型: Article,,卷期:2010年84-20]
- During infection, simian virus 40 (SV40) attempts to take hold of the cell, while the host responds with various defense systems, including the ataxia-telangiectasia mutated/ATM-Rad3 related (ATM/ATR)-mediated DNA damage...
- Envelope-Modified Single-Cycle Simian Immunodeficiency Virus Selectively Enhances Antibody Responses and Partially Protects against Repeated, Low-Dose Vaginal Challenge
[作者:Alpert, MD; Rahmberg, AR; Neidermyer, W; Ng, SK; Carville, A; Camp, JV; Wilson, RL; Piatak, M; Mansfield, KG; Li, WJ; Miller, CJ; Lifson, JD; Kozlowski, PA; Evans, DT,期刊:Journal of virology, 页码:10748-10764 , 文章类型: Article,,卷期:2010年84-20]
- Immunization of rhesus macaques with strains of simian immunodeficiency virus (SIV) that are limited to a single cycle of infection elicits T-cell responses to multiple viral gene products and antibodies capable of neutr...
- Persistence of Genital Tract T Cell Responses in HIV-Infected Women on Highly Active Antiretroviral Therapy
[作者:Mkhize, NN; Gumbi, PP; Liebenberg, LJ; Ren, YA; Smith, P; Denny, L; Passmore, JAS,期刊:Journal of virology, 页码:10765-10772 , 文章类型: Article,,卷期:2010年84-20]
- Initiation of highly active antiretroviral therapy (HAART) for HIV-infected individuals is associated with control of viremia, improved CD4 counts, and declining systemic HIV-specific immune responses. While HAART effect...
- A Single-Amino-Acid Substitution in Herpes Simplex Virus 1 Envelope Glycoprotein B at a Site Required for Binding to the Paired Immunoglobulin-Like Type 2 Receptor alpha (PILR alpha) Abrogates PILR alpha-Dependent Viral Entry and Reduces Pathogenesis
[作者:Arii, J; Wang, J; Morimoto, T; Suenaga, T; Akashi, H; Arase, H; Kawaguchi, Y,期刊:Journal of virology, 页码:10773-10783 , 文章类型: Article,,卷期:2010年84-20]
- Paired immunoglobulin-like type 2 receptor alpha (PILR alpha) is a herpes simplex virus 1 (HSV-1) entry receptor that associates with O-glycans on HSV-1 envelope glycoprotein B (gB). Two threonine residues (Thr-53 and Th...
- Soluble HLA-G Inhibits Myeloid Dendritic Cell Function in HIV-1 Infection by Interacting with Leukocyte Immunoglobulin-Like Receptor B2
[作者:Huang, JH; Burke, P; Yang, Y; Seiss, K; Beamon, J; Cung, T; Toth, I; Pereyra, F; Lichterfeld, M; Yu, XG,期刊:Journal of virology, 页码:10784-10791 , 文章类型: Article,,卷期:2010年84-20]
- Dendritic cells represent a specialized class of professional antigen-presenting cells that are responsible for priming and maintaining antigen-specific effector cell responses and regulating immune activation by cytokin...
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