- Design, synthesis and biological assessment of novel N-substituted 3-(phthalimidin-2-yl)-2,6-dioxopiperidines and 3-substituted 2,6-dioxopiperidines for TNF-alpha inhibitory activity
[作者:LUO WEIMING; YU QIANSHENG; SALCEDO ISIDRO; HOLLOWAY HAROLD W; LAHIRI DEBOMOY K; BROSSI ARNOLD; TWEEDIE DAVID; GREIG NIGEL H,期刊:Bioorganic & Medicinal Chemistry, 页码:3965-3972 , 文章类型: Article,,卷期:2011年19-13]
- Eight novel 2-(2,6-dioxopiperidin-3-yl) phthalimidine EM-12 dithiocarbamates 9 and 10, N-substituted 3-(phthalimidin-2-yl)-2,6-dioxopiperidines 11-14 and 3-substituted 2,6-dioxopiperidines 16and 18were synthesized as tum...
- Synthesis, structural elucidation, DNA-PK inhibition, homology modelling and anti-platelet activity of morpholino-substituted-1,3-naphth-oxazines
[作者:IHMAID SALEH; ALRAWI JASIM; BRADLEY CHRISTOPHER; ANGOVE MICHAEL J; ROBERTSON MURRAY N; CLARK RACHEL L,期刊:Bioorganic & Medicinal Chemistry, 页码:3983-3994 , 文章类型: Article,,卷期:2011年19-13]
- A number of new angular 2-morpholino-(substituted)-naphth-1,3-oxazines (compound 10b), linear 2-morpholino-(substituted)-naphth-1,3-oxazines (compounds 13b-c), linear 6, 7 and 9-0-substituted-2-morpholino-(substituted)-n...
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