- The Global Role of Kidney Transplantation
[作者:Garcia, GG; Harden, P; Chapman, J,期刊:Transplantation, 页码:337-341 , 文章类型: Article,,卷期:2012年93-4]
- World Kidney Day on March 8, 2012, provides a chance to reflect on the success of kidney transplantation as a therapy for end-stage kidney disease that surpasses dialysis treatments both for the quality and quantity of l...
- Current Status of Hepatocyte Transplantation
[作者:Hughes, RD; Mitry, RR; Dhawan, A,期刊:Transplantation, 页码:342-347 , 文章类型: Article,,卷期:2012年93-4]
- Hepatocyte transplantation (HT) has been performed in patients with liver-based metabolic disease and acute liver failure as a potential alternative to liver transplantation. The results are encouraging in genetic liver ...
- Advising Potential Recipients on the Use of Organs From Donors With Primary Central Nervous System Tumors
[作者:Warrens, AN; Birch, R; Collett, D; Daraktchiev, M; Dark, JH; Galea, G; Gronow, K; Neuberger, J; Hilton, D; Whittle, IR; Watson, CJE,期刊:Transplantation, 页码:348-353 , 文章类型: Article,,卷期:2012年93-4]
- Deciding to use an organ from a donor with a primary central nervous system (CNS) tumor necessitates offsetting the risk of tumor transmission with the chances of survival if the patient waits for another offer of a tran...
- Blockade of NKG2D Synergized With CTLA4-Ig in Promoting Long-Term Graft Survival in Murine Models of Cardiac Transplantation
[作者:Li, J; Zhu, HF; Wang, SH; Ye, P; Liu, CG; Wu, J; Xia, JH,期刊:Transplantation, 页码:356-363 , 文章类型: Article,,卷期:2012年93-4]
- Background. Blockade of B7-CD28 interaction with CTLA4-Ig could prolong allograft survival in cardiac transplantation. NKG2D is an activating or coactivating receptor on NK cells, gamma delta T, and CD8(+) T cells and pl...
- Mechanism of Accommodation in a Sensitized Human Leukocyte Antigen Transgenic Murine Cardiac Transplant Model
[作者:Fukami, N; Ramachandran, S; Narayanan, K; Liu, W; Nath, DS; Jendrisak, M; Chapman, W; Mohanakumar, T,期刊:Transplantation, 页码:364-372 , 文章类型: Article,,卷期:2012年93-4]
- Background. Presence of donor-specific antibodies (Abs) is detrimental to posttransplant allograft function. Some sensitized recipients have successfully undergone transplantation after pretransplant conditioning regimen...
- A20-Mediated Modulation of Inflammatory and Immune Responses in Aortic Allografts and Development of Transplant Arteriosclerosis
[作者:Siracuse, JJ; Fisher, MD; da Silva, CG; Peterson, CR; Csizmadia, E; Moll, HP; Damrauer, SM; Studer, P; Choi, LY; Essayagh, S; Kaczmarek, E; Maccariello, ER; Lee, A; Daniel, S; Ferran, C,期刊:Transplantation, 页码:373-382 , 文章类型: Article,,卷期:2012年93-4]
- Background. Transplant arteriosclerosis (TA) is the pathognomonic feature of chronic rejection, the primary cause of allograft failure. We have shown that the NF-kappa B inhibitory protein A20 exerts vasculoprotective ef...
- Drug Interaction Between Cyclosporine and mTOR Inhibitors in Experimental Model of Chronic Cyclosporine Nephrotoxicity and Pancreatic Islet Dysfunction
[作者:Piao, SG; Bae, SK; Lim, SW; Song, JH; Chung, BH; Choi, BS; Yang, CW,期刊:Transplantation, 页码:383-389 , 文章类型: Article,,卷期:2012年93-4]
- Background. It is known that sirolimus (SRL) aggravates cyclosporine A (CsA)-induced nephrotoxicity and pancreatic injury, but the influence of everolimus (EVR) on CsA-induced organ injury is undetermined. Methods. Rats ...
- Comparative Study on Signal Transduction in Endothelial Cells After Anti-A/B and Human Leukocyte Antigen Antibody Reaction: Implication of Accommodation
[作者:Iwasaki, K; Miwa, Y; Ogawa, H; Yazaki, S; Iwamoto, M; Furusawa, T; Onishi, A; Kuzuya, T; Haneda, M; Watarai, Y; Uchida, K; Kobayashi, T,期刊:Transplantation, 页码:390-397 , 文章类型: Article,,卷期:2012年93-4]
- Background. Recent development of immunosuppressive therapy has provided a platform for clinical human leukocyte antigen (HLA)- and ABO-incompatible kidney transplantation. However, the prognosis seems to be different be...
- Everolimus as Primary Immunosuppression in Kidney Transplantation: Experience in Conversion From Calcineurin Inhibitors
[作者:Sanchez-Fructuoso, AI; Ruiz, JC; Calvo, N; Rodrigo, E; Perez-Flores, I; Gomez-Alamillo, C; Fernandez-Perez, C; Arias, M; Barrientos, A,期刊:Transplantation, 页码:398-405 , 文章类型: Article,,卷期:2012年93-4]
- Background. We analyzed our clinical experience with everolimus (EVL) and identified prognostic factors for a successful conversion. Methods. Retrospective study of 220 kidney recipients consecutively converted to EVL wi...
- Chronic Kidney Disease After Nonrenal Solid Organ Transplantation: A Histological Assessment and Utility of Chronic Allograft Damage Index Scoring
[作者:Kubal, C; Cockwell, P; Gunson, B; Jesky, M; Hanvesakul, R; Dronavalli, V; Bonser, RS; Neil, D,期刊:Transplantation, 页码:406-411 , 文章类型: Article,,卷期:2012年93-4]
- Background. It is proposed that chronic calcineurin inhibitor (CNI) nephrotoxicity has a central role in chronic kidney disease after nonrenal solid organ transplantation (NRSOT), although there are little data on renal ...
- Effects of Preexistent Hypertension on Blood Pressure and Residual Renal Function After Donor Nephrectomy
[作者:Tent, H; Sanders, JSF; Rook, M; Hofker, HS; Ploeg, RJ; Navis, G; van der Heide, JJH,期刊:Transplantation, 页码:412-417 , 文章类型: Article,,卷期:2012年93-4]
- Background. Living kidney donor selection has become more liberal with acceptation of hypertensive donors. Here, we evaluate short-term and 1- and 5-year renal outcome of living kidney donors with preexistent hypertensio...
- Allosensitization Rate of Male Patients Awaiting First Kidney Grafts After Leuko-Depleted Blood Transfusion
[作者:Balasubramaniam, GS; Morris, M; Gupta, A; Mesa, IR; Thuraisingham, R; Ashman, N,期刊:Transplantation, 页码:418-422 , 文章类型: Article,,卷期:2012年93-4]
- Background. Blood transfusions are generally avoided for potential renal transplant recipients due to risk of human leukocyte antigen (HLA) allosensitization. Despite the near universal use of erythropoiesis-stimulating ...
- Perceived Discrimination Predicts Longer Time to Be Accepted for Kidney Transplant
[作者:Myaskovsky, L; Doebler, DA; Posluszny, DM; Dew, MA; Unruh, M; Fried, LF; Switzer, GE; Kim, S; Chang, CCH; Ramkumar, M; Shapiro, R,期刊:Transplantation, 页码:423-429 , 文章类型: Article,,卷期:2012年93-4]
- Background. Although end-stage kidney disease in African Americans (AAs) is four times greater than in whites, AAs are less than one half as likely to undergo kidney transplantation (KT). This racial disparity has been f...
- A Randomized Trial With Steroids and Antithymocyte Globulins Comparing Cyclosporine/Azathioprine Versus Tacrolimus/Mycophenolate Mofetil (CATM2) in Renal Transplantation
[作者:Vacher-Coponat, H; Moal, V; Indreies, M; Purgus, R; Loundou, A; Burtey, S; Brunet, P; Moussi-Frances, J; Daniel, L; Dussol, B; Berland, Y,期刊:Transplantation, 页码:437-443 , 文章类型: Article,,卷期:2012年93-4]
- Background. The best immunosuppressive regimen in benefit-risk ratio in renal transplantation is debated. Nowadays, tacrolimus (Tac) and mycophenolate mofetil (MMF) are considered more efficient than cyclosporine A (CsA)...
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