- Helical Repeat Structure of Apoptosis Inhibitor 5 Reveals Protein-Protein Interaction Modules
[作者:Han, BG; Kim, KH; Lee, SJ; Jeong, KC; Cho, JW; Noh, KH; Kim, TW; Kim, SJ; Yoon, HJ; Suh, SW; Lee, S; Lee, BI,期刊:Journal of Biological Chemistry, 页码:10727-10737 , 文章类型: Article,,卷期:2012年287-14]
- Apoptosis inhibitor 5 (API5) is an anti-apoptotic protein that is up-regulated in various cancer cells. Here, we present the crystal structure of human API5. API5 exhibits an elongated all alpha-helical structure. The N-...
- Bromodomain Protein Brd4 Associated with Acetylated Chromatin Is Important for Maintenance of Higher-order Chromatin Structure
[作者:Wang, RR; Li, Q; Helfer, CM; Jiao, J; You, JX,期刊:Journal of Biological Chemistry, 页码:10738-10752 , 文章类型: Article,,卷期:2012年287-14]
- Chromatin structure organization is crucial for regulating many fundamental cellular processes. However, the molecular mechanism that regulates the assembly of higher-order chromatin structure remains poorly understood. ...
- Histone Chaperone Rtt106 Promotes Nucleosome Formation Using (H3-H4)(2) Tetramers
[作者:Fazly, A; Li, Q; Hu, Q; Mer, G; Horazdovsky, B; Zhang, ZG,期刊:Journal of Biological Chemistry, 页码:10753-10760 , 文章类型: Article,,卷期:2012年287-14]
- The yeast histone chaperone Rtt106 is involved in de novo assembly of newly synthesized histones into nucleosomes during DNA replication and plays a role in regulating heterochromatin silencing and maintaining genomic in...
- Structural Basis for Antifreeze Activity of Ice-binding Protein from Arctic Yeast
[作者:Lee, JH; Park, AK; Do, H; Park, KS; Moh, SH; Chi, YM; Kim, HJ,期刊:Journal of Biological Chemistry, 页码:11460-11468 , 文章类型: Article,,卷期:2012年287-14]
- Arctic yeast Leucosporidium sp. produces a glycosylated ice-binding protein (LeIBP) with a molecular mass of similar to 25 kDa, which can lower the freezing point below the melting point once it binds to ice. LeIBP is a ...
- Essential Role of ELOVL4 Protein in Very Long Chain Fatty Acid Synthesis and Retinal Function
[作者:Harkewicz, R; Du, HJ; Tong, ZZ; Alkuraya, H; Bedell, M; Sun, WO; Wang, XL; Hsu, YH; Esteve-Rudd, J; Hughes, G; Su, ZG; Zhang, M; Lopes, VS; Molday, RS; Williams, DS; Dennis, EA; Zhang, K,期刊:Journal of Biological Chemistry, 页码:11469-11480 , 文章类型: Article,,卷期:2012年287-14]
- Very long chain polyunsaturated fatty acid (VLC-PUFA)-containing glycerophospholipids are highly enriched in the retina; however, details regarding the specific synthesis and function of these highly unusual retinal glyc...
- A Detour for Yeast Oxysterol Binding Proteins
[作者:Beh, CT; McMaster, CR; Kozminski, KG; Menon, AK,期刊:Journal of Biological Chemistry, 页码:11481-11488 , 文章类型: Review,,卷期:2012年287-14]
- Oxysterol binding protein-related proteins, including the yeast proteins encoded by the OSH gene family (OSH1-OSH7), are implicated in the non-vesicular transfer of sterols between intracellular membranes and the plasma ...
- Contraction-induced Interleukin-6 Gene Transcription in Skeletal Muscle Is Regulated by c-Jun Terminal Kinase/Activator Protein-1
[作者:Whitham, M; Chan, MHS; Pal, M; Matthews, VB; Prelovsek, O; Lunk, S; El-Osta, A; Broenneke, H; Alber, J; Bruning, JC; Wunderlich, FT; Lancaster, GI; Febbraio, MA,期刊:Journal of Biological Chemistry, 页码:10771-10779 , 文章类型: Article,,卷期:2012年287-14]
- Exercise increases the expression of the prototypical myokine IL-6, but the precise mechanism by which this occurs has yet to be identified. To mimic exercise conditions, C2C12 myotubes were mechanically stimulated via e...
- Role of Cysteine Residues and Disulfide Bonds in the Activity of a Legume Root Nodule-specific, Cysteine-rich Peptide
[作者:Haag, AF; Kerscher, B; Dall'Angelo, S; Sani, M; Longhi, R; Baloban, M; Wilson, HM; Mergaert, P; Zanda, M; Ferguson, GP,期刊:Journal of Biological Chemistry, 页码:10791-10798 , 文章类型: Article,,卷期:2012年287-14]
- The root nodules of certain legumes including Medicago truncatula produce >300 different nodule-specific cysteine-rich (NCR) peptides. Medicago NCR antimicrobial peptides (AMPs) mediate the differentiation of the bacteri...
- Successful Prediction of Substrate-binding Pocket in SLC17 Transporter Sialin
[作者:Pietrancosta, N; Anne, C; Prescher, H; Ruivo, R; Sagne, C; Debacker, C; Bertrand, HO; Brossmer, R; Acher, F; Gasnier, B,期刊:Journal of Biological Chemistry, 页码:11489-11497 , 文章类型: Article,,卷期:2012年287-14]
- Secondary active transporters from the SLC17 protein family are required for excitatory and purinergic synaptic transmission, sialic acid metabolism, and renal function, and several members are associated with inherited ...
- EMILIN-3, Peculiar Member of Elastin Microfibril Interface-located Protein (EMILIN) Family, Has Distinct Expression Pattern, Forms Oligomeric Assemblies, and Serves as Transforming Growth Factor beta (TGF-beta) Antagonist
[作者:Schiavinato, A; Becker, AKA; Zanetti, M; Corallo, D; Milanetto, M; Bizzotto, D; Bressan, G; Guljelmovic, M; Paulsson, M; Wagener, R; Braghetta, P; Bonaldo, P,期刊:Journal of Biological Chemistry, 页码:11498-11515 , 文章类型: Article,,卷期:2012年287-14]
- EMILIN-3 is a glycoprotein of the extracellular matrix belonging to a family that contains a characteristic N-terminal cysteine-rich EMI domain. Currently, EMILIN-3 is the least characterized member of the elastin microf...
- Rapid Aquaporin Translocation Regulates Cellular Water Flow MECHANISM OF HYPOTONICITY-INDUCED SUBCELLULAR LOCALIZATION OF AQUAPORIN 1 WATER CHANNEL
[作者:Conner, MT; Conner, AC; Bland, CE; Taylor, LHJ; Brown, JEP; Parri, HR; Bill, RM,期刊:Journal of Biological Chemistry, 页码:11516-11525 , 文章类型: Article,,卷期:2012年287-14]
- The control of cellular water flow is mediated by the aquaporin (AQP) family of membrane proteins. The structural features of the family and the mechanism of selective water passage through the AQP pore are established, ...
- Role of N-Glycosylation Sites and CXC Motifs in Trafficking of Medicago truncatula Nod Factor Perception Protein to Plasma Membrane
[作者:Lefebvre, B; Klaus-Heisen, D; Pietraszewska-Bogiel, A; Herve, C; Camut, S; Auriac, MC; Gasciolli, V; Nurisso, A; Gadella, TWJ; Cullimore, J,期刊:Journal of Biological Chemistry, 页码:10812-10823 , 文章类型: Article,,卷期:2012年287-14]
- The lysin motif receptor-like kinase, NFP (Nod factor perception), is a key protein in the legume Medicago truncatula for the perception of lipochitooligosaccharidic Nod factors, which are secreted bacterial signals esse...
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