- Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton
[作者:Dawe, HR; Adams, M; Wheway, G; Szymanska, K; Logan, CV; Noegel, AA; Gull, K; Johnson, CA,期刊:Journal of cell science, 页码:2716-2726 , 文章类型: Article,,卷期:2009年122-15]
- Meckel-Gruber syndrome (MKS) is a severe autosomal recessively inherited disorder caused by mutations in genes that encode components of the primary cilium and basal body. Here we show that two MKS proteins, MKS1 and mec...
- Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation
[作者:Stylli, SS; Stacey, TTI; Verhagen, AM; Xu, SS; Pass, I; Courtneidge, SA; Lock, P,期刊:Journal of cell science, 页码:2727-2740 , 文章类型: Article,,卷期:2009年122-15]
- Invadopodia are actin-based projections enriched with proteases, which invasive cancer cells use to degrade the extracellular matrix (ECM). The Phox homology (PX)-Src homology (SH)3 domain adaptor protein Tks5 (also know...
- Tssk6 is required for Izumo relocalization and gamete fusion in the mouse
[作者:Sosnik, J; Miranda, PV; Spiridonov, NA; Yoon, SY; Fissore, RA; Johnson, GR; Visconti, PE,期刊:Journal of cell science, 页码:2741-2749 , 文章类型: Article,,卷期:2009年122-15]
- One of the most important processes in fertilization is the fusion of egg and sperm; however, the molecular mechanisms involved in this process are not well understood. So far, using genetic approaches, only two proteins...
- FAM29A, a target of Plk1 regulation, controls the partitioning of NEDD1 between the mitotic spindle and the centrosomes
[作者:Zhu, H; Fang, K; Fang, GW,期刊:Journal of cell science, 页码:2750-2759 , 文章类型: Article,,卷期:2009年122-15]
- We previously showed that FAM29A, a spindle-associated protein, promotes microtubule-dependent microtubule amplification through its interaction with and recruitment of NEDD1, the targeting subunit of the gamma-tubulin r...
- Growth arrest induces primary-cilium formation and sensitizes IGF-1-receptor signaling during differentiation induction of 3T3-L1 preadipocytes
[作者:Zhu, D; Shi, S; Wang, HZ; Liao, K,期刊:Journal of cell science, 页码:2760-2768 , 文章类型: Article,,卷期:2009年122-15]
- The first stage of 3T3-L1 adipocyte differentiation is growth arrest, which is achieved by contact inhibition at confluence. In growth-arrested confluent 3T3-L1 preadipocytes, alpha-tubulin acetylation and primary-cilium...
- FAK, PIP5KI gamma and gelsolin cooperatively mediate force-induced expression of alpha-smooth muscle actin
[作者:Chan, MWC; Arora, PD; Bozavikov, P; McCulloch, CA,期刊:Journal of cell science, 页码:2769-2781 , 文章类型: Article,,卷期:2009年122-15]
- During the development of pressure-induced cardiac hypertrophy, fibroblasts are activated to become myofibroblasts, which exhibit actin-cytoskeletal remodeling and express alpha-smooth muscle actin (SMA; encoded by ACTA2...
- The yeast endocytic protein Epsin 2 functions in a cell-division signaling pathway (vol 122, pg 2453, 2009)
[作者:Mukherjee, D; Coon, BG; Edwards, DF; Hanna, CB; Longhi, SA; McCaffery, JM; Wendland, B; Retegui, LA; Bi, E; Aguilar, RC,期刊:Journal of cell science, 页码:2782-2782 , 文章类型: Correction,,卷期:2009年122-15]
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- Nicotiana tabacum TTG1 contributes to ParA1-induced signalling and cell death in leaf trichomes
[作者:Wang, YP; Liu, RX; Chen, L; Wang, YC; Liang, YC; Wu, XJ; Li, BY; Wu, JD; Liang, Y; Wang, XM; Zhang, CL; Wang, QX; Hong, XY; Dong, HS,期刊:Journal of cell science, 页码:2673-2685 , 文章类型: Review,,卷期:2009年122-15]
- Leaf trichomes serve as a physical barrier and can also secrete antimicrobial compounds to protect plants from attacks by insects and pathogens. Besides the use of the physical and chemical mechanisms, leaf trichomes mig...
- PML-IV functions as a negative regulator of telomerase by interacting with TERT
[作者:Oh, W; Ghim, J; Lee, EW; Yang, MR; Kim, ET; Ahn, JH; Song, J,期刊:Journal of cell science, 页码:2613-2622 , 文章类型: Article,,卷期:2009年122-15]
- Maintaining proper telomere length requires the presence of the telomerase enzyme. Here we show that telomerase reverse transcriptase ( TERT), a catalytic component of telomerase, is recruited to promyelocytic leukemia (...
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