- Proteasomal inhibition alters the trafficking of the neurotrophin receptor TrkA
[作者:Moises, T; Wuller, S; Saxena, S; Senderek, J; Weis, J; Kruttgen, A,期刊:Biochemical and Biophysical Research Communications, 页码:360-364 , 文章类型: Article,,卷期:2009年387-2]
- Neurotrophin receptors of the Trk family promote neuronal survival. The signal transduction of Trk receptors is regulated by endosomal trafficking. Monoubiquitination of receptor tyrosine kinases is an established signal...
- FATP1 mediates fatty acid-induced activation of AMPK in 3T3-L1 adipocytes
[作者:Wiczer, BM; Lobo, S; Machen, GL; Graves, LM; Bernlohr, DA,期刊:Biochemical and Biophysical Research Communications, 页码:234-238 , 文章类型: Article,,卷期:2009年387-2]
- Fatty acid transport proteins are integral membrane acyl-CoA synthetases implicated in adipocyte fatty acid influx and esterification. FATP-dependent production of AMP was evaluated using FATP4 proteoliposomes, and fatty...
- Aldo-keto reductase family 1 B10 protein detoxifies dietary and lipid-derived alpha, beta-unsaturated carbonyls at physiological levels
[作者:Zhong, LL; Liu, ZW; Yan, RL; Johnson, S; Zhao, YP; Fang, XB; Cao, DL,期刊:Biochemical and Biophysical Research Communications, 页码:245-250 , 文章类型: Article,,卷期:2009年387-2]
- Alpha, beta-unsaturated carbonyls are highly reactive mutagens and carcinogens to which humans are exposed on a daily basis. This study demonstrates that aldo-keto reductase family 1 member B10 (AKR1B10) is a critical pr...
- Pharmacological characterization of INCB3344, a small molecule antagonist of human CCR2
[作者:Shin, N; Baribaud, F; Wang, K; Yang, GJ; Wynn, R; Covington, MB; Feldman, P; Gallagher, KB; Leffet, LM; Lo, YY; Wang, AL; Xue, CB; Newton, RC; Scherle, PA,期刊:Biochemical and Biophysical Research Communications, 页码:251-255 , 文章类型: Article,,卷期:2009年387-2]
- The chemokine receptor 2 (CCR2) directs migration of monocytes and has been proposed to be a drug target for chronic inflammatory diseases. INCB3344 was first published as a small molecule nanomolar inhibitor of rodent C...
- Cellular protein TTRAP interacts with HIV-1 integrase to facilitate viral integration
[作者:Zhang, JQ; Wang, JJ; Li, WJ; Huang, L; Tian, L; Xue, JL; Chen, JZ; Jia, W,期刊:Biochemical and Biophysical Research Communications, 页码:256-260 , 文章类型: Article,,卷期:2009年387-2]
- TTRAP is a PML-NB protein that is involved in the NF-kappa B signaling pathway. TTRAP was recently identified by yeast two-hybrid analysis as a HIV-1 integrase (HIV-1 IN) interacting protein. This interaction was verifie...
- Prediction of efficacy of anti-TNF biologic agent, infliximab, for rheumatoid arthritis patients using a comprehensive transcriptome analysis of white blood cells
[作者:Tanino, M; Matoba, R; Nakamura, S; Kameda, H; Amano, K; Okayama, T; Nagasawa, H; Suzuki, K; Matsubara, K; Takeuchi, T,期刊:Biochemical and Biophysical Research Communications, 页码:261-265 , 文章类型: Article,,卷期:2009年387-2]
- Introduction of biologics, Such as infliximab, to the therapy of rheumatoid arthritis (RA) patients has revolutionized the treatment of this disease. However, biomarkers for predicting the efficacy of the drug at an earl...
- Gangliosides are involved in neural differentiation of human dental pulp-derived stem cells
[作者:Ryu, JS; Ko, K; Lee, JW; Park, SB; Byun, SJ; Jeong, EJ; Ko, K; Choo, YK,期刊:Biochemical and Biophysical Research Communications, 页码:266-271 , 文章类型: Article,,卷期:2009年387-2]
- Human dental pulp-derived stem cells (hDPSCs) have been considered alternative sources of adult stem cells because of their potential to differentiate into multiple cell lineages. This study investigated the possible rol...
- OsBWMK1 mediates SA-dependent defense responses by activating the transcription factor OsWRKY33
[作者:Koo, SC; Moon, BC; Kim, JK; Kim, CY; Sung, SJ; Kim, MC; Cho, MJ; Cheong, YH,期刊:Biochemical and Biophysical Research Communications, 页码:365-370 , 文章类型: Article,,卷期:2009年387-2]
- Mitogen-activated protein kinases (MAPKs) play important roles in responses to various environmental stresses. In a previous study, we demonstrated that OsBWMK1, which localizes in the nucleus, mediates PR gene expressio...
- Caspases regulate VAMP-8 expression and phagocytosis in dendritic cells
[作者:Ho, YHS; Cai, DT; Huang, DC; Wang, CC; Wong, SH,期刊:Biochemical and Biophysical Research Communications, 页码:371-375 , 文章类型: Article,,卷期:2009年387-2]
- During an inflammation and upon encountering pathogens, immature dendritic cells (DC) undergo a maturation process to become highly efficient in presenting antigens. This transition from immature to mature state is accom...
- AdDLP, a bacterial defensin-like peptide, exhibits anti-Plasmodium activity
[作者:Gao, B; Rodriguez, MD; Lanz-Mendoza, H; Zhu, SY,期刊:Biochemical and Biophysical Research Communications, 页码:393-398 , 文章类型: Article,,卷期:2009年387-2]
- Antimicrobial defensins with the cysteine-stabilized alpha-helical and beta-sheet (CS alpha beta) motif are widely distributed in three eukaryotic kingdoms. However, recent work suggests that bacteria Could possess defen...
- Active transcription of the human FAS/CD95/TNFRSF6 gene involves the p53 family
[作者:Schilling, T; Schleithoff, ES; Kairat, A; Melino, G; Stremmel, W; Oren, M; Krammer, PH; Muller, M,期刊:Biochemical and Biophysical Research Communications, 页码:399-404 , 文章类型: Article,,卷期:2009年387-2]
- p63 and p73 express two main classes of isoforms: isoforms which contain the transactivation domain (TAp73 and TAp63) executing transcriptional activity and dominant-negative isoforms which are truncated at the NH2-termi...
- Hemagglutinin and neuraminidase matching patterns of two influenza A virus strains related to the 1918 and 2009 global pandemics
[作者:Zhang, YH; Lin, XJ; Zhang, FW; Wu, J; Tan, WJ; Bi, SL; Zhou, JF; Shu, YL; Wang, Y,期刊:Biochemical and Biophysical Research Communications, 页码:405-408 , 文章类型: Article,,卷期:2009年387-2]
- The current pandemic influenza A (H1N1) virus has revealed a complicated reassortment of various influenza A Viruses. The biological study of these viruses, especially of the viral envelope proteins hemagglutinin (HA) an...
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