- Perilipin Controls Lipolysis by Regulating the Interactions of AB-hydrolase Containing 5 (Abhd5) and Adipose Triglyceride Lipase (Atgl)
[作者:Granneman, JG; Moore, HPH; Krishnamoorthy, R; Rathod, M,期刊:Journal of Biological Chemistry, 页码:34538-34544 , 文章类型: Article,,卷期:2009年284-50]
- The mobilization of stored lipid by hormones is a fundamental function of fat cells, and there is strong evidence that perilipin (Plin), a lipid droplet scaffold, and adipose tissue triglyceride lipase (Atgl), a triglyce...
- MTA1 Coregulator Regulates p53 Stability and Function
[作者:Li, DQ; Reddy, SDN; Pakala, SB; Wu, XF; Zhang, YP; Rayala, SK; Kumar, R,期刊:Journal of Biological Chemistry, 页码:34545-34552 , 文章类型: Article,,卷期:2009年284-50]
- Although metastasis-associated protein 1 (MTA1) has recently been shown as a DNA damage responsive protein, the underlying mechanism for its role in DNA double-strand break (DSB) repair remains unknown. Here, we show tha...
- X Chromosome-linked Inhibitor of Apoptosis Regulates Cell Death Induction by Proapoptotic Receptor Agonists
[作者:Varfolomeev, E; Alicke, B; Elliott, JM; Zobel, K; West, K; Wong, H; Scheer, JM; Ashkenazi, A; Gould, SE; Fairbrother, WJ; Vucic, D,期刊:Journal of Biological Chemistry, 页码:34553-34560 , 文章类型: Article,,卷期:2009年284-50]
- Proapoptotic receptor agonists cause cellular demise through the activation of the extrinsic and intrinsic apoptotic pathways. Inhibitor of apoptosis (IAP) proteins block apoptosis induced by diverse stimuli. Here, we de...
- Targeted Knockdown of EGR-1 Inhibits IL-8 Production and IL-8-mediated Invasion of Prostate Cancer Cells through Suppressing EGR-1/NF-kappa B Synergy
[作者:Ma, JJ; Ren, ZJ; Ma, Y; Xu, L; Zhao, Y; Zheng, CG; Fang, YH; Xue, T; Sun, BL; Xiao, WH,期刊:Journal of Biological Chemistry, 页码:34600-34606 , 文章类型: Article,,卷期:2009年284-50]
- IL-8 produced by prostate cancer cells may be responsible for the androgen-independent growth of advanced prostate cancers. Accumulating evidence from microarray analyses and animal genetic models highlights the central ...
- Sunday Driver Interacts with Two Distinct Classes of Axonal Organelles
[作者:Abe, N; Almenar-Queralt, A; Lillo, C; Shen, ZX; Lozach, J; Briggs, SP; Williams, DS; Goldstein, LSB; Cavalli, V,期刊:Journal of Biological Chemistry, 页码:34628-34639 , 文章类型: Article,,卷期:2009年284-50]
- The extreme polarized morphology of neurons poses a challenging problem for intracellular trafficking pathways. The distant synaptic terminals must communicate via axonal transport with the cell soma for neuronal surviva...
- Intracellular Expression of a Single Domain Antibody Reduces Cytotoxicity of 15-Acetyldeoxynivalenol in Yeast
[作者:Doyle, PJ; Saeed, H; Hermans, A; Gleddie, SC; Hussack, G; Arbabi-Ghahroudi, M; Seguin, C; Savard, ME; MacKenzie, CR; Hall, JC,期刊:Journal of Biological Chemistry, 页码:35029-35039 , 文章类型: Article,,卷期:2009年284-50]
- 15-Acetyldeoxynivalenol (15-AcDON) is a low molecular weight sesquiterpenoid trichothecene mycotoxin associated with Fusarium ear rot of maize and Fusarium head blight of small grain cereals. The accumulation of mycotoxi...
- Cwp84, a Surface-associated Cysteine Protease, Plays a Role in the Maturation of the Surface Layer of Clostridium difficile
[作者:Kirby, JM; Ahern, H; Roberts, AK; Kumar, V; Freeman, Z; Acharya, KR; Shone, CC,期刊:Journal of Biological Chemistry, 页码:34666-34673 , 文章类型: Article,,卷期:2009年284-50]
- Clostridium difficile is a major and growing problem as a hospital-associated infection that can cause severe, recurrent diarrhea. The mechanism by which the bacterium colonizes the gut during infection is poorly underst...
- G Protein-coupled Receptor Kinases Phosphorylate LRP6 in the Wnt Pathway
[作者:Chen, MY; Philipp, M; Wang, JB; Premont, RT; Garrison, TR; Caron, MG; Lefkowitz, RJ; Chen, W,期刊:Journal of Biological Chemistry, 页码:35040-35048 , 文章类型: Article,,卷期:2009年284-50]
- Wnt ligands conduct their functions in canonical Wnt signaling by binding to two receptors, the single transmembrane low density lipoprotein receptor-related proteins 5 and 6 (LRP5/6) and seven transmembrane (7TM) Frizzl...
- HIV-1 Accessory Protein Vpu Internalizes Cell-surface BST-2/Tetherin through Transmembrane Interactions Leading to Lysosomes
[作者:Iwabu, Y; Fujita, H; Kinomoto, M; Kaneko, K; Ishizaka, Y; Tanaka, Y; Sata, T; Tokunaga, K,期刊:Journal of Biological Chemistry, 页码:35060-35072 , 文章类型: Article,,卷期:2009年284-50]
- Bone marrow stromal antigen 2 (BST-2, also known as tetherin) is a recently identified interferon-inducible host restriction factor that can block the production of enveloped viruses by trapping virus particles at the ce...
- Replication Protein A Stimulates the Werner Syndrome Protein Branch Migration Activity
[作者:Sowd, G; Wang, H; Pretto, D; Chazin, WJ; Opresko, PL,期刊:Journal of Biological Chemistry, 页码:34682-34691 , 文章类型: Article,,卷期:2009年284-50]
- Loss of the RecQ DNA helicase WRN protein causes Werner syndrome, in which patients exhibit features of premature aging and increased cancer. WRN deficiency induces cellular defects in DNA replication, mitotic homologous...
- Histidine 379 of Human Laeverin/Aminopeptidase Q, a Nonconserved Residue within the Exopeptidase Motif, Defines Its Distinctive Enzymatic Properties
[作者:Maruyama, M; Arisaka, N; Goto, Y; Ohsawa, Y; Inoue, H; Fujiwara, H; Hattori, A; Tsujimoto, M,期刊:Journal of Biological Chemistry, 页码:34692-34702 , 文章类型: Article,,卷期:2009年284-50]
- Human laeverin/aminopeptidase Q (LVRN/APQ) is a novel member of the M1 family of zinc aminopeptidases and is specifically expressed on the cell surface of human extravillous trophoblasts. Multiple sequence alignment of h...
- Calcium Bridge Triggers Capsid Disassembly in the Cell Entry Process of Simian Virus 40
[作者:Kawano, MA; Xing, L; Tsukamoto, H; Inoue, T; Handa, H; Cheng, RH,期刊:Journal of Biological Chemistry, 页码:34703-34712 , 文章类型: Article,,卷期:2009年284-50]
- The calcium bridge between the pentamers of polyoma viruses maintains capsid metastability. It has been shown that viral infection is profoundly inhibited by the substitution of lysine for glutamate in one calcium-bindin...
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