- Genetic changes of Wnt pathway genes are common events in metaplastic carcinomas of the breast
[作者:Hayes, MJ; Thomas, D; Emmons, A; Giordano, TJ; Kleer, CG,期刊:Clinical Cancer Research, 页码:4038-4044 , 文章类型: Article,,卷期:2008年14-13]
- Purpose: Metaplastic carcinomas are distinct invasive breast carcinomas with aberrant nonglandular differentiation, which may be spindle, squamous, or chondroid. The limited effective treatments result from the lack of k...
- Carcinoembryonic antigen cell adhesion molecule 6 predicts breast cancer recurrence following adjuvant tamoxifen (vol 14, pg 405, 2008)
[作者:Maraqa, L; Cummings, M; Peter, MB; Shaaban, AM; Horgan, K; Hanby, AM; Speirs, V,期刊:Clinical Cancer Research, 页码:4355-4356 , 文章类型: Correction,,卷期:2008年14-13]
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- Activation of Notch signaling in a xenograft model of brain metastasis
[作者:Nam, DH; Jeon, HM; Kim, S; Kim, MH; Lee, YJ; Lee, MS; Kim, H; Joo, KM; Lee, DS; Price, JE; Bang, SI; Park, WY,期刊:Clinical Cancer Research, 页码:4059-4066 , 文章类型: Article,,卷期:2008年14-13]
- Purpose: The potential of metastasis can be predicted from clinical features like tumor size, histologic grade, and gene expression patterns. We examined the whole-genome transcriptomic profile of a xenograft model of br...
- Increased prevalence of EGFR-mutant lung cancer in women and in East Asian populations: Analysis of estrogen-related polymorphisms
[作者:Bell, DW; Brannigan, BW; Matsu, K; Finkelstein, DM; Sordella, R; Settleman, J; Mitsudomi, T; Haber, DA,期刊:Clinical Cancer Research, 页码:4079-4084 , 文章类型: Article,,卷期:2008年14-13]
- Purpose: Somatic mutations in the epidermal growth factor receptor (EGFR) gene occur in a subset of non - small-cell lung cancer (NSCLC) and are highly predictive of the clinical response to selective EGFR kinase inhibit...
- Mitogen-activated protein kinase activation in lung adenocarcinoma: A comparative study between ever smokers and never smokers
[作者:Mountzios, G; Planchard, D; Besse, B; Validire, P; Girard, P; Devisme, C; Dimopoulos, MA; Soria, JC; Fouret, P,期刊:Clinical Cancer Research, 页码:4096-4102 , 文章类型: Article,,卷期:2008年14-13]
- Purpose: There are major differences affecting genes in adenocarcinomas in ever and never smokers. However, data on whether mitogen-activated protein kinase (MAPK) activation state differs according to smoking status are...
- Osteopontin and interleukin-8 expression is independently associated with prostate cancer recurrence
[作者:Caruso, DJ; Carmack, AJK; Lokeshwar, VB; Duncan, RC; Soloway, MS; Lokeshwar, BL,期刊:Clinical Cancer Research, 页码:4111-4118 , 文章类型: Article,,卷期:2008年14-13]
- Purpose: Lack of reliable biomarkers limits accurate prediction of prostate - specific antigen biochemical recurrence (disease progression) in prostate cancer. The two inflammatory chemokines, osteopontin and interleukin...
- Clinical significance of CXC chemokine receptor-4 and c-Met in childhood rhabdomyosarcoma
[作者:Diomedi-Camassei, F; McDowell, HP; De Loris, MA; Uccini, S; Altavista, P; Raschella, G; Vitali, R; Mannarino, O; De Sio, L; Cozzi, DA; Donfrancesco, A; Inserra, A; Callea, F; Dominici, C,期刊:Clinical Cancer Research, 页码:4119-4127 , 文章类型: Article,,卷期:2008年14-13]
- Purpose:The CXC chemokine receptor-4 (CXCR4)/stromal-derived factor-1 and c-Met/hepatocyte growth factor axes promote the metastatic potential of rhabdomyosarcoma cell lines in experimental models, but no data are availa...
- Multiple mechanisms of telomere maintenance exist and differentially affect clinical outcome in diffuse malignant peritoneal mesothelioma
[作者:Villa, R; Daidone, MG; Motta, R; Venturini, L; De Marco, C; Vannelli, A; Kusamura, S; Baratti, D; Deraco, M; Costa, A; Reddel, RR; Zaffaroni, N,期刊:Clinical Cancer Research, 页码:4134-4140 , 文章类型: Article,,卷期:2008年14-13]
- Purpose: This study aims to investigate the prevalence of the two known telomere maintenance mechanisms, telomerase activity (TA) and alternative lengthening of telomeres (ALT), and to assess their prognostic relevance i...
- Molecular risk stratification of medulloblastoma patients based on immunohistochemical analysis of MYC, LDHB, and CCNB1 expression
[作者:de Haas, T; Hasselt, N; Troost, D; Caron, H; Popovic, M; Zadravec-Zaletel, L; Grajkowska, W; Perek, M; Osterheld, MC; Ellison, D; Baas, F; Versteeg, R; Kool, M,期刊:Clinical Cancer Research, 页码:4154-4160 , 文章类型: Article,,卷期:2008年14-13]
- Purpose: Medulloblastoma is the most common malignant embryonal brain tumor in children. The current clinical risk stratification to select treatment modalities is not optimal because it does not identify the standard-ri...
- Gene expression profiles of luteal phase fallopian tube epithelium from BRCA mutation carriers resemble high-grade serous carcinoma
[作者:Tone, AA; Begley, H; Sharma, M; Murphy, J; Rosen, B; Brown, TJ; Shaw, PA,期刊:Clinical Cancer Research, 页码:4067-4078 , 文章类型: Article,,卷期:2008年14-13]
- Purpose: To identify molecular alterations potentially involved in predisposition to adnexal serous carcinoma (SerCa) in the nonmalignant fallopian tube epithelium (FTE) of BRCA1/2 mutation carriers, given recent evidenc...
- Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma
[作者:Chiou, SH; Yu, CC; Huang, CY; Lin, SC; Liu, CJ; Tsai, TH; Chou, SH; Chien, CS; Ku, HH; Lo, JF,期刊:Clinical Cancer Research, 页码:4085-4095 , 文章类型: Article,,卷期:2008年14-13]
- Purpose: Oral squamous cell carcinoma (OSCC), like many solid tumors, contains a heterogeneous population of cancer cells. Recent data suggest that a rare subpopulation of cancer cells, termed cancer stem cells (CSC), is...
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