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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共43条记录   Delineation of TMPRSS2-ERG splice variants in prostate cancer [作者：Hu, Y; Dobi, A; Sreenath, T; Cook, C; Tadase, AY; Ravindranath, L; Cullen, J; Furusato, B; Chen, Y; Thangapazham, RL; Mohamed, A; Sun, C; Sesterhenn, IA; McLeod, DG; Petrovics, G; Srivastava, S,期刊：Clinical Cancer Research, 页码：4719-4725 , 文章类型： Article，,卷期：2008年14-15] Purpose: The expression of the ETS-related gene (ERG) is low or undetectable in benign prostate epithelial cells. High prevalence of ERG overexpression in prostate cancer cells due to TMPRSS2-ERG fusions suggest for caus... Prospective study of the accuracy of EGFR mutational analysis by high-resolution melting analysis in small samples obtained from patients with non-small cell lung cancer [作者：Fukui, T; Ohe, Y; Tsuta, K; Furuta, K; Sakamoto, H; Takano, T; Nokihara, H; Yamamoto, N; Sekine, I; Kunitoh, H; Asamura, H; Tsuchida, T; Kaneko, M; Kusumoto, M; Yamamoto, S; Yoshida, T; Tamura, T,期刊：Clinical Cancer Research, 页码：4751-4757 , 文章类型： Article，,卷期：2008年14-15] Purpose: Epidermal growth factor receptor (EGFR) mutations, especially in-frame deletions in exon 19 (DEL) and a point mutation in exon 21 (L858R), predict gefitinib sensitivity in patients with non-small cell lung cance... Prognostic significance of CD55 expression in breast cancer [作者：Ikeda, J; Morii, E; Liu, Y; Qiu, Y; Nakamichi, N; Jokoji, R; Miyoshi, Y; Noguchi, S; Aozasa, K,期刊：Clinical Cancer Research, 页码：4780-4786 , 文章类型： Article，,卷期：2008年14-15] Purpose: Our recent study revealed that CD55-high population in breast cancer cell line was resistant to apoptosis and formed colonies in vitro more efficiently than CD55-low population. The present study was conducted t... The genetics of castration-resistant prostate cancer: What can the germline tell us? [作者：Sharifi, N; Dahut, WL; Figg, WD,期刊：Clinical Cancer Research, 页码：4691-4693 , 文章类型： Article，,卷期：2008年14-15] Androgen deprivation therapy (ADT) is the cornerstone treatment for advanced prostate cancer. Despite frequent responses, the majority of metastatic tumors will progress to castration-resistant prostate cancer. Numerous ... Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: Implications for STAT-3 activation and gene expression [作者：Brantley, EC; Nabors, LB; Gillespie, GY; Choi, YH; Palmer, CA; Harrison, K; Roarty, K; Benveniste, EN,期刊：Clinical Cancer Research, 页码：4694-4704 , 文章类型： Article，,卷期：2008年14-15] Purpose: STATs activate transcription in response to numerous cytokines, controlling proliferation, gene expression, and apoptosis. Aberrant activation of STAT proteins, particularly STAT-3, is implicated in the pathogen... Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors [作者：Nickerson, ML; Jaeger, E; Shi, Y; Durocher, JA; Mahurkar, S; Zaridze, D; Matveev, V; Janout, V; Kollarova, H; Bencko, V; Navratilova, M; Szeszenia-Dabrowska, N; Mates, D; Mukeria, A; Holcatova, I; Schmidt, LS; Toro, JR; Karami, S; Hung, R; Gerard, GF; Linehan, WM; Merino, M; Zbar, B; Boffetta, P; Brennan, P; Rothman, N; Chow, WH; Waldman, FM; Moore, LE,期刊：Clinical Cancer Research, 页码：4726-4734 , 文章类型： Article，,卷期：2008年14-15] Purpose: To provide a comprehensive, thorough analysis of somatic mutation and promoter hypermethylation of the von Hippel-Lindau (VHL) gene in the cancer genome, unique to clear cell renal cancer (ccRCC). Identify relat... Imaging of urokinase-type plasminogen activator receptor expression using a Cu-64-labeled linear peptide antagonist by microPET [作者：Li, ZB; Niu, G; Wang, H; He, LN; Yang, LL; Ploug, M; Chen, XY,期刊：Clinical Cancer Research, 页码：4758-4766 , 文章类型： Article，,卷期：2008年14-15] Purpose: Malignant tumors are capable of degrading the surrounding extracellular matrix, resulting in local invasion or metastasis. Urokinase-type plasminogen activator (uPA) and its cell surface receptor (uPAR) are cent... Pattern of serum autoantibodies allows accurate distinction between a tumor and pathologies of the same organ [作者：Ludwig, N; Keller, A; Comtesse, N; Rheinheimer, S; Pallasch, C; Fischer, U; Fassbender, K; Steudel, WI; Lenhof, HP; Meese, E,期刊：Clinical Cancer Research, 页码：4767-4774 , 文章类型： Article，,卷期：2008年14-15] Purpose: Recent studies impressively showed the diagnostic potential of seroreactivity patterns for different tumor types, offering the prospect for low-cost screening of numerous tumor types simultaneously. One of the m... Genetic polymorphisms of metastasis suppressor gene NME1 and breast cancer survival [作者：Qu, SM; Long, JR; Cai, QY; Shu, XO; Cai, H; Gao, YT; Zheng, W,期刊：Clinical Cancer Research, 页码：4787-4793 , 文章类型： Article，,卷期：2008年14-15] Purpose: Ample evidence supports an important role of tumor metastasis suppressor genes in cancer metastatic processes. We evaluated the association of genetic polymorphisms of metastasis suppressor gene NME1 with breast... Human papillomavirus type 16/18 up-regulates the expression of interleukin-6 and antiapoptotic Mcl-1 in non-small cell lung cancer [作者：Cheng, YW; Lee, H; Shiau, MY; Wu, TC; Huang, TT; Chang, YH,期刊：Clinical Cancer Research, 页码：4705-4712 , 文章类型： Article，,卷期：2008年14-15] Purpose: Human papillomavirus (HPV) 16/18 infection is reported to be associated with nonsmoking Taiwanese female lung cancer. In this study, we attempted to further reveal the association between HPV infection with Mcl-... Gene expression profiling of papillary thyroid carcinoma identifies transcripts correlated with BRAF mutational status and lymph node metastasis [作者：Oler, G; Camacho, CP; Hojaij, FC; Michaluart, P; Riggins, GJ; Cerutti, JM,期刊：Clinical Cancer Research, 页码：4735-4742 , 文章类型： Article，,卷期：2008年14-15] Purpose: To identify papillary thyroid carcinoma (PTC)-associated transcripts, we compared the gene expression profiles of three Serial Analysis of Gene Expression libraries generated from thyroid tumors and a normal thy... The Retinoblastoma family member pRb2/p130 is an independent predictor of survival in human soft tissue sarcomas [作者：Masciullo, V; Berardengo, E; Boglione, A; Sgambato, A; Bernardi, A; Forni, M; Linari, A; Cito, L; Scambia, G; Comandone, A; Giordano, A,期刊：Clinical Cancer Research, 页码：4775-4779 , 文章类型： Article，,卷期：2008年14-15] Purpose: pRb2/p130, a member of the Retinoblastoma gene family, has been shown to be a powerful prognostic factor in several malignancies. We sought to evaluate pRb2/p130 protein expression and its clinical effect in pat... Three-gene expression signature predicts survival in early-stage squamous cell carcinoma of the lung [作者：Skrzypski, M; Jassem, E; Taron, M; Sanchez, JJ; Mendez, P; Rzyman, W; Gulida, G; Raz, D; Jablons, D; Provencios, M; Massuti, B; Chaib, M; Perez-Roca, L; Jassem, J; Rosell, R,期刊：Clinical Cancer Research, 页码：4794-4799 , 文章类型： Article，,卷期：2008年14-15] Purpose: Adjuvant treatment may improve survival in early-stage squamous cell carcinoma (SCC) of the lung; however, the absolute gain is modest and mainly limited to stage II-IIIA. Current staging methods are imprecise i... Moving toward individualized cancer therapies [作者：Tonon, G; Anderson, KC,期刊：Clinical Cancer Research, 页码：4682-4684 , 文章类型： Article，,卷期：2008年14-15] In vivo analysis of the gene expression profiles of cancer cells before and after treatment in patients may define mechanisms of sensitivity and resistance to specific drugs and ultimately allow for the selection of opti... Erythropoiesis-stimulating agent use in cancer: Preclinical and clinical perspectives [作者：Arcasoy, MO,期刊：Clinical Cancer Research, 页码：4685-4690 , 文章类型： Article，,卷期：2008年14-15] Erythropoiesis-stimulating agents (ESA) used for the treatment of chemotherapy-induced anemia in cancer patients have been associated with adverse outcomes of enhanced tumor progression and impaired survival in a series ... OPG is regulated by beta-catenin and mediates resistance to TRAIL-induced apoptosis in colon cancer [作者：De Toni, EN; Thieme, SE; Herbst, A; Behrens, A; Stieber, P; Jung, A; Blum, H; Goke, B; Kolligs, FT,期刊：Clinical Cancer Research, 页码：4713-4718 , 文章类型： Article，,卷期：2008年14-15] Purpose: Resistance to apoptosis is a hallmark of cancer and correlates with aggressiveness of tumors and poor prognosis. The Wnt/beta-catenin pathway plays a pivotal role in the genesis of colorectal cancer by mechanism...