- The translational research working group developmental pathways: Introduction and overview
[作者:Hawk, ET; Matrisian, LM; Nelson, WG; Dorfman, GS; Stevens, L; Kwok, J; Viner, J; Hautala, J; Grad, O,期刊:Clinical Cancer Research, 页码:5664-5671 , 文章类型: Article,,卷期:2008年14-18]
- The Translational Research Working Group (TRWG) was created as a national initiative to evaluate the current status of the National Cancer Institute's investment in translational research and envision its future in an in...
- Translational research working group developmental pathway for biospecimen-based assessment modalities
[作者:Srivastava, S; Gray, JW; Reid, BJ; Grad, O; Greenwood, A; Hawk, ET,期刊:Clinical Cancer Research, 页码:5672-5677 , 文章类型: Article,,卷期:2008年14-18]
- The Translational Research Working Group (TRWG) was created as a national initiative to evaluate the current status of National Cancer Institute's investment in translational research and envision its future. The TRWG co...
- The translational research working group developmental pathway for image-based assessment modalities
[作者:Dorfman, GS; Sullivan, DC; Schnall, MD; Matrisian, LM,期刊:Clinical Cancer Research, 页码:5678-5684 , 文章类型: Article,,卷期:2008年14-18]
- The Image-based assessment modality (IM) pathway refers to one of six Translational Research Working Group (TRWG) pathways that, together, describe the core domains of early translational cancer research. This pathway fo...
- The translational research working group developmental pathway for anticancer agents (drugs or biologics)
[作者:Schilsky, RL; Gordon, G; Gilmer, TM; Courtneidge, SA; Matrisian, LM; Grad, O; Nelson, WG,期刊:Clinical Cancer Research, 页码:5685-5691 , 文章类型: Article,,卷期:2008年14-18]
- The Translational Research Working Group (TRWG) was created as a national initiative to evaluate the current status of the National Cancer Institute's investment in translational research and envision its future, The TRW...
- Translational research working group developmental pathway for immune response modifiers
[作者:Cheever, MA; Schlom, J; Weiner, LM; Lyerly, HK; Disis, ML; Greenwood, A; Grad, O; Nelson, WG,期刊:Clinical Cancer Research, 页码:5692-5699 , 文章类型: Article,,卷期:2008年14-18]
- The Translational Research Working Group (TRWG) was created as a national initiative to evaluate the current status of the investment of National Cancer Institute in translational research and envision its future. The Tr...
- The translational research working group developmental pathway for lifestyle alterations
[作者:Hawk, ET; Greenwood, A; Gritz, ER; McTiernan, A; Sellers, T; Hursting, SD; Leischow, S; Grad, O,期刊:Clinical Cancer Research, 页码:5707-5713 , 文章类型: Article,,卷期:2008年14-18]
- The Translational Research Working Group (TRWG) was created as a national initiative to evaluate the current status of National Cancer Institute's investment in translational research and envision its future. The TRWG co...
- Type III transforming growth factor-beta (TGF-beta) receptor mediates apoptosis in renal cell carcinoma independent of the canonical TGF-beta signaling pathway
[作者:Margulis, V; Maity, T; Zhang, XY; Cooper, SJ; Copland, JA; Wood, CG,期刊:Clinical Cancer Research, 页码:5722-5730 , 文章类型: Article,,卷期:2008年14-18]
- Purpose: Alterations in transforming growth factor-p (TGF-beta) signaling occur early during malignant transformation of renal epithelial cells and are associated with loss of type III TGF-beta receptor (T beta RIII) exp...
- Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma
[作者:Riely, GJ; Kris, MG; Rosenbaum, D; Marks, J; Li, A; Chitale, DA; Nafa, K; Riedel, ER; Su, MH; Pao, W; Miller, VA; Ladanyi, M,期刊:Clinical Cancer Research, 页码:5731-5734 , 文章类型: Article,,卷期:2008年14-18]
- Purpose: KRAS mutations are found in similar to 25% of lung adenocarcinomas in Western countries and, as a group, have been strongly associated with cigarette smoking. These mutations are predictive of poor prognosis in ...
- Control of cell growth and survival by enzymes of the fatty acid synthesis pathway in HCT-116 colon cancer cells
[作者:Zhan, Y; Ginanni, N; Tota, MR; Wu, M; Bays, NW; Richon, VM; Kohl, NE; Bachman, ES; Strack, PR; Krauss, S,期刊:Clinical Cancer Research, 页码:5735-5742 , 文章类型: Article,,卷期:2008年14-18]
- Purpose: For many tumor cells, de novo lipogenesis is a requirement for growth and survival. A considerable body of work suggests that inhibition of this pathway may be a powerful approach to antineoplastic therapy. It h...
- Tris (Dibenzylideneacetone) dipalladium, a N-myristoyltransferase-1 inhibitor, is effective against melanoma growth in vitro and in vivo
[作者:Bhandarkar, SS; Bromberg, J; Carrillo, C; Selvakumar, P; Sharma, RK; Perry, BN; Govindarajan, B; Fried, L; Sohn, A; Reddy, K; Arbiser, JL,期刊:Clinical Cancer Research, 页码:5743-5748 , 文章类型: Article,,卷期:2008年14-18]
- Purpose: Melanoma is a solid tumor that is notoriously resistant to chemotherapy, and its incidence is rapidly increasing. Recently, several signaling pathways have been shown to contribute to melanoma tumorigenesis, inc...
|