- Nuclear Factor-kappa B p65/relA Silencing Induces Apoptosis and Increases Gemcitabine Effectiveness in a Subset of Pancreatic Cancer Cells
[作者：Pan, X; Arumugam, T; Yamamoto, T; Levin, PA; Ramachandran, V; Ji, B; Lopez-Berestein, G; Vivas-Mejia, PE; Sood, AK; McConkey, DJ; Logsdon, CD,期刊：Clinical Cancer Research, 页码：8143-8151 , 文章类型： Article，,卷期：2008年14-24]
- Purpose: Nuclear factor kappa B (NF kappa B) activity may increase survival and protect cancer cells from chemotherapy. Therefore, NF kappa B activity may be prognostic, and inhibition of NF kappa B may be useful for pan...
- Protein Expression Profiling in Esophageal Adenocarcinoma Patients Indicates Association of Heat-Shock Protein 27 Expression and Chemotherapy Response
[作者：Langer, R; Ott, K; Specht, K; Becker, K; Lordick, F; Burian, M; Herrmann, K; Schrattenholz, A; Cahill, MA; Schwaiger, M; Hofler, H; Wester, HJ,期刊：Clinical Cancer Research, 页码：8279-8287 , 文章类型： Article，,卷期：2008年14-24]
- Purpose: To identify pretherapeutic predictive biomarkers in tumor biopsies of patients with locally advanced esophageal adenocarcinomas treated with neoadjuvant chemotherapy, we used an explorative proteomic approach to...
- Triple-Negative Breast Cancer: Risk Factors to Potential Targets
[作者：Schneider, BP; Winer, EP; Foulkes, WD; Garber, J; Perou, CM; Richardson, A; Sledge, GW; Carey, LA,期刊：Clinical Cancer Research, 页码：8010-8018 , 文章类型： Article，,卷期：2008年14-24]
- Triple-negative breast cancer has recently been recognized as an important subgroup of breast cancer with a distinct outcome and therapeutic approach when compared with other subgroups of breast cancer. Triple-negative b...
- Regulation of CD151 by Hypoxia Controls Cell Adhesion and Metastasis in Colorectal Cancer
[作者：Chien, CW; Lin, SC; Lai, YY; Lin, BW; Lin, SC; Lee, JC; Tsai, SJ,期刊：Clinical Cancer Research, 页码：8043-8051 , 文章类型： Article，,卷期：2008年14-24]
- Purpose: The first step of metastasis is the detachment of cancer cells from the surrounding matrix and neighboring cells; however, how cancer cells accomplish this process remains unclear. Thus, we aimed to investigate ...
- Neuropilin-2-Mediated Tumor Growth and Angiogenesis in Pancreatic Adenocarcinoma
[作者：Dallas, NA; Gray, MJ; Xia, L; Fan, F; van Buren, G; Gaur, P; Samuel, S; Lim, SJ; Arumugam, T; Ramachandran, V; Wang, HM; Ellis, LM,期刊：Clinical Cancer Research, 页码：8052-8060 , 文章类型： Article，,卷期：2008年14-24]
- Purpose. Neuropilin-2 (NRP-2) is a coreceptor for vascular endothelial growth factor (VEGF) on endothelial cells. NRP-2 is overexpressed in pancreatic ductal adenocarcinoma (PDAC) cells relative to nonmalignant ductal ep...
- DNA Copy-Number Alterations Underlie Gene Expression Differences between Microsatellite Stable and Unstable Colorectal Cancers
[作者：Jorissen, RN; Lipton, L; Gibbs, P; Chapman, M; Desai, J; Jones, IT; Yeatman, TJ; East, P; Tomlinson, IPM; Verspaget, HW; Aaltonen, LA; Kruhoffer, M; Orntoft, TF; Andersen, CL; Sieber, OM,期刊：Clinical Cancer Research, 页码：8061-8069 , 文章类型： Article，,卷期：2008年14-24]
- Purpose: About 15% of colorectal cancers harbor microsatellite instability (MSI). MSI-associated gene expression changes have been identified in colorectal cancers, but little overlap exists between signatures hindering ...
- Inhibition of Melanoma Growth by Targeting of Antigen to Dendritic Cells via an Anti-DEC-205 Single-Chain Fragment Variable Molecule
[作者：Johnson, TS; Mahnke, K; Storn, V; Schonfeld, K; Ring, S; Nettelbeck, DM; Haisma, HJ; Le Gall, F; Kontermann, RE; Enk, AH,期刊：Clinical Cancer Research, 页码：8169-8177 , 文章类型： Article，,卷期：2008年14-24]
- Purpose: Our goal was to target melanoma antigens to the dendritic cell-specific receptor DEC-205. DEC-205 is an antigen receptor expressed on dendritic cells and has been shown to guide antigens to MHC class I and II co...
- Cytosolic Phospholipase A(2)-alpha: A Potential Therapeutic Target for Prostate Cancer
[作者：Patel, MI; Singh, J; Niknami, M; Kurek, C; Yao, M; Lu, S; Maclean, F; King, NJC; Gelb, MH; Scott, KF; Russell, PJ; Boulas, J; Dong, Q,期刊：Clinical Cancer Research, 页码：8070-8079 , 文章类型： Article，,卷期：2008年14-24]
- Purpose: Cytosolic phospholipase A2-alpha (cPLA(2)-alpha provides intracellular arachidonic acid to supply both cyclooxygenase and lipoxygenase pathways. We aim to determine the expression and activation of cPLA(2)-alpha...
- The Novel Nuclear Factor-kappa B Inhibitor LC-1 Is Equipotent in Poor Prognostic Subsets of Chronic Lymphocytic Leukemia and Shows Strong Synergy with Fludarabine
[作者：Hewamana, S; Lin, TT; Jenkins, C; Burnett, AK; Jordan, CT; Fegan, C; Brennan, P; Rowntree, C; Pepper, C,期刊：Clinical Cancer Research, 页码：8102-8111 , 文章类型： Article，,卷期：2008年14-24]
- Purpose: We have recently shown that the novel nuclear factor-kappa B (NF-kappa B) inhibitor LC-1 is effective in primary chronic lymphocytic leukemia (CLL) cells. Here we elucidated the mechanism of action of LC-1 evalu...
- Reduction of Human Melanoma Tumor Growth in Severe Combined Immunodeficient Mice by Passive Transfer of Antibodies Induced by a High Molecular Weight Melanoma-Associated Antigen Mimotope Vaccine
[作者：Wagner, S; Krepler, C; Allwardt, D; Latzka, J; Strommer, S; Scheiner, O; Pehamberger, H; Wiedermann, U; Hafner, C; Breiteneder, H,期刊：Clinical Cancer Research, 页码：8178-8183 , 文章类型： Article，,卷期：2008年14-24]
- Purpose: The high molecular weight melanoma-associated antigen (HMW-MAA) is an attractive target for immunotherapy of malignant melanoma. We have recently generated a vaccine based on the HMW-MAA mimotope 225D9.2(+) that...
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