- Application of targeted drug delivery system in Chinese medicine
[作者:Li, DC; Zhong, XK; Zeng, ZP; Jiang, JG; Li, L; Zhao, MM; Yang, XQ; Chen, J; Zhang, BS; Zhao, QZ; Xie, MY; Xiong, H; Deng, ZY; Zhang, XM; Xu, SY; Gao, YX,期刊:Journal of controlled release, 页码:103-112 , 文章类型: Review,,卷期:2009年138-2]
- Targeted drug delivery system of traditional Chinese medicine (TCM) refers to those using different carriers to make the effective parts or monomer extracted from TCM or natural medicine into agents which can directly co...
- Mechanistic study of the adjuvant effect of biodegradable nanoparticles in mucosal vaccination
[作者:Slutter, B; Plapied, L; Fievez, V; Sande, MA; des Rieux, A; Schneider, YJ; Van Riet, E; Jiskoot, W; Preat, V,期刊:Journal of controlled release, 页码:113-121 , 文章类型: Article,,卷期:2009年138-2]
- For oral vaccination, incorporation of antigens into nanoparticles has been shown to protect the antigen from degradation, but may also increase its uptake through the intestinal epithelium via M-cells. The aim of this s...
- Enhanced intracellular delivery using arginine-rich peptides by the addition of penetration accelerating sequences (Pas)
[作者:Takayama, K; Nakase, I; Michiue, H; Takeuchi, T; Tomizawa, K; Matsui, H; Futaki, S,期刊:Journal of controlled release, 页码:128-133 , 文章类型: Article,,卷期:2009年138-2]
- Cell penetrating peptides (CPPs), including arginine-rich peptides, are attractive tools for the intracellular delivery of various bioactive molecules with a low membrane permeability. We showed that the accelerated intr...
- Transcutaneous immunization using common chemicals
[作者:Karande, P; Arora, A; Pham, TK; Stevens, D; Wojicki, A; Mitragotri, S,期刊:Journal of controlled release, 页码:134-140 , 文章类型: Article,,卷期:2009年138-2]
- Transcutaneous immunization, topical application of vaccines on skin, provides several advantages over needle based immunization. However, simple topical application of vaccines does not generate sufficient immune respon...
- Efficient intracellular siRNA delivery strategy through rapid and simple two steps mixing involving noncovalent post-PEGylation
[作者:Kong, WH; Sung, DK; Shim, YH; Bae, KH; Dubois, P; Park, TG; Kim, JH; Seo, SW,期刊:Journal of controlled release, 页码:141-147 , 文章类型: Article,,卷期:2009年138-2]
- Two different and well-defined methacrylate-based (co)polymers were employed as a polymeric siRNA delivery system. siRNA, poly(2-(dimethylamino) ethyl methacrylate) homopolymers (PDMAEMA) and poly (2-(dimethylamino) ethy...
- Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: Effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging
[作者:Merkel, OM; Librizzi, D; Pfestroff, A; Schurrat, T; Buyens, K; Sanders, NN; De Smedt, SC; Behe, M; Kissel, T,期刊:Journal of controlled release, 页码:148-159 , 文章类型: Article,,卷期:2009年138-2]
- in search of optimizing siRNA delivery systems for systemic application, one critical parameter remains their stability in blood circulation. In this study, we have traced pharmacokinetics and biodistribution of each com...
- Enhanced gene expression by a novel stearylated INF7 peptide derivative through fusion independent endosomal escape
[作者:El-Sayed, A; Masuda, T; Khalil, I; Akita, H; Harashima, H,期刊:Journal of controlled release, 页码:160-167 , 文章类型: Article,,卷期:2009年138-2]
- An octaarginine-modified multifunctional envelope-type nano device (R8-MEND) was previously reported to be an efficient nonviral vector for the delivery of plasmid DNA, in vitro and after topical administration. We repor...
- Enhanced angiogenesis mediated by vascular endothelial growth factor plasmid-loaded thermo-responsive amphiphilic polymer in a rat myocardial infarction model
[作者:Kwon, JS; Park, IK; Cho, AS; Shin, SM; Hong, MH; Jeong, SY; Kim, YS; Min, JJ; Jeong, MH; Kim, WJ; Jo, S; Pun, SH; Cho, JG; Park, JC; Kang, JC; Ahn, Y,期刊:Journal of controlled release, 页码:168-176 , 文章类型: Article,,卷期:2009年138-2]
- Thermo-responsive hydrogel-mediated gene transfer may be preferred for the muscle, because the release of DNA into the surrounding tissue can be controlled by the 3-dimensional structure of the hydrogel. Such a system fo...
- Quantification of plasmid DNA copies in the nucleus after lipoplex and polyplex transfection (vol 135, pg 166, 2009)
[作者:Cohen, RN; van der Aa, MAEM; Macaraeg, N; Lee, AP; Szoka, FC,期刊:Journal of controlled release, 页码:185-185 , 文章类型: Correction,,卷期:2009年138-2]
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