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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共25条记录   RNA editing competence of trans-factor MEF1 is modulated by ecotype-specific differences but requires the DYW domain [作者：Zehrmann, A; Verbitskiy, D; Hartel, B; Brennicke, A; Takenaka, M,期刊：FEBS Letters, 页码：4181-4186 , 文章类型： Article，,卷期：2010年584-19] RNA editing in plant mitochondria posttranscriptionally changes multiple cytidines to uridines. The RNA editing trans-factor MEF1 was identified via ecotype-specific editing polymorphisms in Arabidopsis thaliana. Complem... Fas activation in adipocytes impairs insulin-stimulated glucose uptake by reducing Akt [作者：Wueest, S; Rapold, RA; Schoenle, EJ; Konrad, D,期刊：FEBS Letters, 页码：4187-4192 , 文章类型： Article，,卷期：2010年584-19] Fas (CD95) belongs to the superfamily of the tumor necrosis factor (TNF) receptors. Besides its key role in apoptosis, Fas contributes to non-apoptotic pathways such as cell proliferation and inflammation. In 3T3-L1 adip... Predicted bacteriorhodopsin from Exiguobacterium sibiricum is a functional proton pump [作者：Petrovskaya, LE; Lukashev, EP; Chupin, VV; Sychev, SV; Lyukmanova, EN; Kryukova, EA; Ziganshin, RH; Spirina, EV; Rivkina, EM; Khatypov, RA; Erokhina, LG; Gilichinsky, DA; Shuvalov, VA; Kirpichnikov, MP,期刊：FEBS Letters, 页码：4193-4196 , 文章类型： Article，,卷期：2010年584-19] The predicted Exigobacterium sibiricum bacterirhodopsin gene was amplified from an ancient Siberian permafrost sample. The protein bacteriorhodopsin from Exiguobacterium sibiricum (ESR) encoded by this gene was expressed... A glycyl free radical as the precursor in the synthesis of carbon monoxide and cyanide by the [FeFe]-hydrogenase maturase HydG [作者：Nicolet, Y; Martin, L; Tron, C; Fontecilla-Camps, JC,期刊：FEBS Letters, 页码：4197-4202 , 文章类型： Article，,卷期：2010年584-19] HydG uses tyrosine to synthesize the CN-/CO ligands of [FeFe]-hydrogenase active site. We have mutated two of the [4Fe-4S]-cluster cysteine ligands of the HydG C-terminal domain (CTD) to serine. The double mutant can sti... Long range dynamic effects of point-mutations trap a response regulator in an active conformation [作者：Bobay, BG; Thompson, RJ; Hoch, JA; Cavanagh, J,期刊：FEBS Letters, 页码：4203-4207 , 文章类型： Article，,卷期：2010年584-19] When a point-mutation in a protein elicits a functional change, it is most common to assign this change to local structural perturbations. Here we show that point-mutations, distant from an essential highly dynamic kinas... Allosteric rescuing of loss-of-function FFAR2 mutations [作者：Swaminath, G; Jaeckel, P; Guo, Q; Cardozo, M; Weiszmann, J; Lindberg, R; Wang, YC; Schwandner, R; Li, Y,期刊：FEBS Letters, 页码：4208-4214 , 文章类型： Article，,卷期：2010年584-19] FFAR2 (GPR43) is a receptor for short-chain fatty acids (SCFAs), acetate and propionate. In the current study, we investigate the molecular determinants contributing to receptor activation by endogenous ligands. Mutation... A novel blue fluorescent chlorophyll catabolite accumulates in senescent leaves of the peace lily and indicates a split path of chlorophyll breakdown [作者：Krautler, B; Banala, S; Moser, S; Vergeiner, C; Muller, T; Lutz, C; Holzinger, A,期刊：FEBS Letters, 页码：4215-4221 , 文章类型： Article，,卷期：2010年584-19] Colorless, non-fluorescent Chl-catabolites (NCCs) are the typical, ubiquitous products of chlorophyll (Chl)-breakdown in senescent leaves. However, a fluorescent Chl-catabolite (FCC) accumulated in de-greened leaves of S... Solution structure of the N-terminal catalytic domain of human H-REV107-A novel circular permutated NlpC/P60 domain [作者：Ren, XB; Lin, JA; Jin, CW; Xia, B,期刊：FEBS Letters, 页码：4222-4226 , 文章类型： Article，,卷期：2010年584-19] H-REV107 is a Ca2+-independent phospholipase A(1/2), and it is also a pro-apoptosis protein belonging to the novel class II tumor suppressor family, H-REV107-like family. Here we report the solution structure of the N-te... Role of prostaglandin E2 in peptidoglycan mediated iNOS expression in mouse peritoneal macrophages in vitro [作者：Dahiya, Y; Pandey, RK; Bhatt, KH; Sodhi, A,期刊：FEBS Letters, 页码：4227-4232 , 文章类型： Article，,卷期：2010年584-19] Many extracellular stimuli, e. g. microbial products, cytokines etc., result in the expression of inducible nitric oxide synthase (iNOS) in macrophages. However, it is not known whether expression of the iNOS gene in res... Interplay between I308 and Y310 residues in the third repeat of microtubule-binding domain is essential for tau filament formation [作者：Naruto, K; Minoura, K; Okuda, R; Taniguchi, T; In, Y; Ishida, T; Tomoo, K,期刊：FEBS Letters, 页码：4233-4236 , 文章类型： Article，,卷期：2010年584-19] Investigation of the mechanism of tau polymerization is indispensable for finding inhibitory conditions or identifying compounds preventing the formation of paired helical filament or oligomers. Tau contains a microtubul... Coevolution is a short-distance force at the protein interaction level and correlates with the modular organization of protein networks [作者：Liang, Z; Xu, M; Teng, MK; Niu, LW; Wu, JR,期刊：FEBS Letters, 页码：4237-4240 , 文章类型： Article，,卷期：2010年584-19] We investigated what roles coevolution plays in shaping yeast protein interaction network (PIN). We found that the extent of coevolution between two proteins decreases rapidly as their interacting distance on the PIN inc... SHP2 is a downstream target of ZAP70 to regulate JAK1/STAT3 and ERK signaling pathways in mouse embryonic stem cells [作者：Cha, Y; Park, KS,期刊：FEBS Letters, 页码：4241-4246 , 文章类型： Article，,卷期：2010年584-19] Previous research indicated that ZAP70, a Syk family tyrosine kinase, is expressed in mouse embryonic stem cells (mESCs) and regulates the Janus kinase 1 (JAK1)/signal transducer and activator of transcription 3 (STAT3) ... Truncation of subunit ND2 disrupts the threefold symmetry of the antiporter-like subunits in complex I from higher metazoans [作者：Birrell, JA; Hirst, J,期刊：FEBS Letters, 页码：4247-4252 , 文章类型： Article，,卷期：2010年584-19] Three of the conserved, membrane-bound subunits in NADH: ubiquinone oxidoreductase (complex I) are related to one another, and to Mrp sodium-proton antiporters. Recent structural analysis of two prokaryotic complexes I r... Counteracting MDM2-induced HIPK2 downregulation restores HIPK2/p53 apoptotic signaling in cancer cells [作者：Nardinocchi, L; Puca, R; Givol, D; D'Orazi, G,期刊：FEBS Letters, 页码：4253-4258 , 文章类型： Article，,卷期：2010年584-19] Homeodomain-interacting protein kinase-2 (HIPK2) is a crucial regulator of p53 apoptotic function by phosphorylating serine 46 (Ser46) in response to DNA damage. In tumors with wild-type p53, its tumor suppressor functio... EGCG functions through estrogen receptor-mediated activation of ADAM10 in the promotion of non-amyloidogenic processing of APP [作者：Fernandez, JW; Rezai-Zadeh, K; Obregon, D; Tan, J,期刊：FEBS Letters, 页码：4259-4267 , 文章类型： Article，,卷期：2010年584-19] Estrogen depletion following menopause has been correlated with an increased risk of developing Alzheimer's disease (AD). We previously explored the beneficial effect of (-)-epigallocatechin-3-gallate (EGCG) on AD mice a... TGF beta enforces activation of eukaryotic elongation factor-2 (eEF2) via inactivation of eEF2 kinase by p90 ribosomal S6 kinase (p90Rsk) to induce mesangial cell hypertrophy [作者：Das, F; Ghosh-Choudhury, N; Kasinath, BS; Choudhury, GG,期刊：FEBS Letters, 页码：4268-4272 , 文章类型： Article，,卷期：2010年584-19] eEF2 phosphorylation is under tight control to maintain mRNA translation elongation. We report that TGF beta activates eEF2 by decreasing eEF2 phosphorylation and simultaneously increasing eEF2 kinase phosphorylation. Re...