个性化文献订阅>文章检索

文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共12条记录   Crystal Structure and Role of Glycans and Dimerization in Folding of Neuronal Leucine-Rich Repeat Protein AMIGO-1 [作者：Kajander, T; Kuja-Panula, J; Rauvala, H; Goldman, A,期刊：Journal of Molecular Biology, 页码：1001-1015 , 文章类型： Article，,卷期：2011年413-5] AMIGO-1 is the parent member of a novel family of three cell surface leucine-rich repeat (LRR) proteins. Its expression is induced by the binding of HMGB1 (high-mobility group box 1 protein) to RAGE (receptor for advance... Molecular Mechanism of Transcription Inhibition by Phage T7 gp2 Protein [作者：Mekler, V; Minakhin, L; Sheppard, C; Wigneshweraraj, S; Severinov, K,期刊：Journal of Molecular Biology, 页码：1016-1027 , 文章类型： Article，,卷期：2011年413-5] Escherichia coli T7 bacteriophage gp2 protein is a potent inhibitor of host RNA polymerase (RNAP). gp2 inhibits formation of open promoter complex by binding to the beta' jaw, an RNAP domain that interacts with downstrea... Tilt-Pair Analysis of Images from a Range of Different Specimens in Single-Particle Electron Cryomicroscopy [作者：Henderson, R; Chen, SX; Chen, JZ; Grigorieff, N; Passmore, LA; Ciccarelli, L; Rubinstein, JL; Crowther, RA; Stewart, PL; Rosenthal, PB,期刊：Journal of Molecular Biology, 页码：1028-1046 , 文章类型： Article，,卷期：2011年413-5] The comparison of a pair of electron microscope images recorded at different specimen tilt angles provides a powerful approach for evaluating the quality of images, image-processing procedures, or three-dimensional struc... Hotspot-Centric De Novo Design of Protein Binders [作者：Fleishman, SJ; Corn, JE; Strauch, EM; Whitehead, TA; Karanicolas, J; Baker, D,期刊：Journal of Molecular Biology, 页码：1047-1062 , 文章类型： Article，,卷期：2011年413-5] Protein protein interactions play critical roles in biology, and computational design of interactions could be useful in a range of applications. We describe in detail a general approach to de novo design of protein inte... The Evidence of Large-Scale DNA-Induced Compaction in the Mycobacterial Chromosomal ParB [作者：Chaudhuri, BN; Dean, R,期刊：Journal of Molecular Biology, 页码：901-907 , 文章类型： Article，,卷期：2011年413-5] The bacterial chromosome trafficking apparatus or the segrosome participates in the mitotic-like segregation of the chromosomes prior to cell division in several bacteria. ParB, which is the parS DNA-binding component of... The C0C1 Fragment of Human Cardiac Myosin Binding Protein C Has Common Binding Determinants for Both Actin and Myosin [作者：Lu, YL; Kwan, AH; Trewhella, J; Jeffries, CM,期刊：Journal of Molecular Biology, 页码：908-913 , 文章类型： Article，,卷期：2011年413-5] The N-terminal domains of cardiac myosin binding protein C (MyBP-C) play a regulatory role in modulating interactions between myosin and actin during heart muscle contraction. Using NIvIR spectroscopy and small-angle neu... Reengineering Cro Protein Functional Specificity with an Evolutionary Code [作者：Hall, BM; Vaughn, EE; Begaye, AR; Cordes, MHJ,期刊：Journal of Molecular Biology, 页码：914-928 , 文章类型： Article，,卷期：2011年413-5] Cro proteins from different lambdoid bacteriophages are extremely variable in their target consensus DNA sequences and constitute an excellent model for evolution of transcription factor specificity. We experimentally te... Novel Structural Insights into Rotavirus Recognition of Ganglioside Glycan Receptors [作者：Yu, X; Coulson, BS; Fleming, FE; Dyason, JC; von Itzstein, M; Blanchard, H,期刊：Journal of Molecular Biology, 页码：929-939 , 文章类型： Article，,卷期：2011年413-5] Rotaviruses ubiquitously infect children under the age of 5, being responsible for more than half a million diarrhoeal deaths each year worldwide. Host cell oligosaccharides containing sialic acid(s) are critical for att... Functional Characterization of Fdx1: Evidence for an Evolutionary Relationship between P450-Type and ISC-Type Ferredoxins [作者：Ewen, KM; Hannemann, F; Lametti, S; Morleo, A; Bernhardt, R,期刊：Journal of Molecular Biology, 页码：940-951 , 文章类型： Article，,卷期：2011年413-5] Ferredoxins are ubiquitous proteins with electron transfer activity involved in a variety of biological processes. In this work, we investigated the characteristics and function of Fdx1 from Sorangium cellulosum So ce56 ... High-Throughput Genetic Identification of Functionally Important Regions of the Yeast DEAD-Box Protein Mss116p [作者：Mohr, G; Del Campo, M; Turner, KG; Gilman, B; Wolf, RZ; Lambowitz, AM,期刊：Journal of Molecular Biology, 页码：952-972 , 文章类型： Article，,卷期：2011年413-5] The Saccharomyces cerevisiae DEAD-box protein Mss116p is a general RNA chaperone that functions in splicing mitochondrial group I and group II introns. Recent X-ray crystal structures of Mss116p in complex with ATP analo... Heparin Activates PKR by Inducing Dimerization [作者：Anderson, E; Pierre-Louis, WS; Wong, CJ; Lary, JW; Cole, JL,期刊：Journal of Molecular Biology, 页码：973-984 , 文章类型： Article，,卷期：2011年413-5] Protein kinase R (PKR) is an interferon-induced kinase that plays a pivotal role in the innate immunity pathway. PKR is activated to undergo autophosphorylation upon binding to double-stranded RNAs or RNAs that contain d... Crystal Structure of the Passenger Domain of the Escherichia coil Autotransporter EspP [作者：Khan, S; Mian, HS; Sandercock, LE; Chirgadze, NY; Pai, EF,期刊：Journal of Molecular Biology, 页码：985-1000 , 文章类型： Article，,卷期：2011年413-5] Autotransporters represent a large superfamily of known and putative virulence factors produced by Gram-negative bacteria. They consist of an N-terminal "passenger domain" responsible for the specific effector functions ...