- A Repeated Coiled-Coil Interruption in the Escherichia coli Condensin MukB
[作者:Weitzel, CS; Waldman, VM; Graham, TA; Oakley, MG,期刊:Journal of Molecular Biology, 页码:578-595 , 文章类型: Article,,卷期:2011年414-4]
- MukB, a divergent structural maintenance of chromosomes (SMC) protein, is important for chromosome segregation and condensation in Escherichia coli and other gamma-proteobacteria. MukB and canonical SMC proteins share a ...
- Crystal Structure of Human Prostate-Specific Antigen in a Sandwich Antibody Complex
[作者:Stura, EA; Muller, BH; Bossus, M; Michel, S; Jolivet-Reynaud, C; Ducancel, F,期刊:Journal of Molecular Biology, 页码:530-544 , 文章类型: Article,,卷期:2011年414-4]
- Human prostate-specific antigen (PSA or human kallikrein-related peptidase 3) present in small quantities in the sera of healthy men becomes elevated in prostate cancer (PCa) and other prostate disorders. The ability to ...
- In Vitro Affinity Maturation of an Anti-PSA Antibody for Prostate Cancer Diagnostic Assay
[作者:Muller, BH; Savatier, A; L'Hostis, G; Costa, N; Bossus, M; Michel, S; Ott, C; Becquart, L; Ruffion, A; Stura, EA; Ducancel, F,期刊:Journal of Molecular Biology, 页码:545-562 , 文章类型: Article,,卷期:2011年414-4]
- Prostate-specific antigen (PSA) is a serum marker that is widely used for the diagnosis of prostatic diseases. Various subforms of free PSA, which are associated with prostate cancer differently, have been identified in ...
- The Crystal Structure Analysis of Group B Streptococcus Sortase C1: A Model for the "Lid" Movement upon Substrate Binding
[作者:Khare, B; Fu, ZQ; Huang, IH; Ton-That, H; Narayana, SVL,期刊:Journal of Molecular Biology, 页码:563-577 , 文章类型: Article,,卷期:2011年414-4]
- A unique feature of the class-C-type sortases, enzymes essential for Gram-positive pilus biogenesis, is the presence of a flexible "lid" anchored in the active site. However, the mechanistic details of the "lid" displace...
- Structural Basis for Myopathic Defects Engendered by Alterations in the Myosin Rod
[作者:Cammarato, A; Li, XC; Reedy, MC; Lee, CF; Lehman, W; Bernstein, SI,期刊:Journal of Molecular Biology, 页码:477-484 , 文章类型: Article,,卷期:2011年414-4]
- While mutations in the myosin subfragment 1 motor domain can directly disrupt the generation and transmission of force along myofibrils and lead to myopathy, the mechanism whereby mutations in the myosin rod influences m...
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