- Isolation and characterization of the core single-stranded DNA-binding domain of purine-rich element binding protein B (Pur beta)
[作者:Rumora, AE; Steere, AN; Ramsey, JE; Knapp, AM; Ballif, BA; Kelm, RJ,期刊:Biochemical and Biophysical Research Communications, 页码:340-345 , 文章类型: Article,,卷期:2010年400-3]
- Pur beta is a single-stranded nucleic acid-binding protein implicated in the injury-induced repression of genes encoding certain muscle-restricted isoforms of actin and myosin expressed in the heart, skeletal muscle, and...
- The structural mechanism of the inhibition of archaeal RelE toxin by its cognate RelB antitoxin
[作者:Shinohara, M; Guo, JX; Mori, M; Nakashima, T; Takagi, H; Nishimoto, E; Yamashita, S; Tsumoto, K; Kakuta, Y; Kimura, M,期刊:Biochemical and Biophysical Research Communications, 页码:346-351 , 文章类型: Article,,卷期:2010年400-3]
- The archaeal toxin, aRelE, in the hyperthermophilic archaeon Pyrococcus horikoshu OT3 inhibits protein synthesis, whereas its cognate antitoxin, aRelB, neutralizes aRelE activity by forming a non-toxic complex, aRelB-aRe...
- Antifungal properties and mode of action of psacotheasin, a novel knottin-type peptide derived from Psacothea hilaris
[作者:Hwang, B; Hwang, JS; Lee, J; Lee, DG,期刊:Biochemical and Biophysical Research Communications, 页码:352-357 , 文章类型: Article,,卷期:2010年400-3]
- Psacotheasin is a 34-mer knottin-type peptide that is derived from Psacothea hilaris larvae In this study, the antifungal activity and mechanism(s) by which psacotheasin affects human fungal pathogens were investigated P...
- Differentiation of human neural progenitor cells regulated by Wnt-3a
[作者:Hubner, R; Schmole, AC; Liedmann, A; Frech, MJ; Rolls, A; Luo, JK,期刊:Biochemical and Biophysical Research Communications, 页码:358-362 , 文章类型: Article,,卷期:2010年400-3]
- Wnt ligands play pivotal roles in the control of cell growth and differentiation during central nervous system development via the Wnt signaling pathway In this study, we investigated the effects of Wnt-3a and beta-caten...
- Mutagenesis of tGCN5 core region reveals two critical surface residues F90 and R140
[作者:Mehta, KR; Chan, YM; Lee, MX; Yang, CY; Voloshchuk, N; Montclare, JK,期刊:Biochemical and Biophysical Research Communications, 页码:363-368 , 文章类型: Article,,卷期:2010年400-3]
- Tetrahymena General Control Non-Derepressor 5 (tGCN5) is a critical regulator of gene transcription via acetylation of histones Since the acetylation ability has been attributed to the "core region", we perform mutagenes...
- The adipokine leptin increases skeletal muscle mass and significantly alters skeletal muscle miRNA expression profile in aged mice
[作者:Hamrick, MW; Herberg, S; Arounleut, P; He, HZ; Shiver, A; Qi, RQ; Zhou, L; Isales, CM; Mi, QS,期刊:Biochemical and Biophysical Research Communications, 页码:379-383 , 文章类型: Article,,卷期:2010年400-3]
- Age-associated loss of muscle mass, or sarcopenia. contributes directly to frailty and an increased risk of falls and fractures among the elderly Aged mice and elderly adults both show decreased muscle mass as well as re...
- Bc13-dependent stabilization of CtBP1 is crucial for the inhibition of apoptosis and tumor progression in breast cancer
[作者:Choi, HJ; Lee, JM; Kim, H; Nam, HJ; Shin, HJR; Kim, D; Ko, E; Noh, DY; Kim, KI; Kim, JH; Baek, SH,期刊:Biochemical and Biophysical Research Communications, 页码:396-402 , 文章类型: Article,,卷期:2010年400-3]
- B-cell lymphoma 3 (Bcl3) is a proto-oncogene upregulated in a wide range of cancers, including breast cancer Although Bcl3 is known to promote cell proliferation and inhibit apoptosis, the molecular mechanisms underlying...
- Non-acylated Mycobacterium bovis glycoprotein MPB83 binds to TLR1/2 and stimulates production of matrix metalloproteinase 9
[作者:Chambers, MA; Whelan, AO; Spallek, R; Singh, M; Coddeville, B; Guerardel, Y; Elass, E,期刊:Biochemical and Biophysical Research Communications, 页码:403-408 , 文章类型: Article,,卷期:2010年400-3]
- A variety of Mycobacterium tuberculosis cell wall components induce expression of matrix metalloproteinase 9 (MMP-9) by monocytic cells and levels of MMP-9 in vivo positively correlate with severity of disease. Toll-like...
- BAG3 directly associates with guanine nucleotide exchange factor of Rap1, PDZGEF2, and regulates cell adhesion
[作者:Iwasaki, M; Tanaka, R; Hishiya, A; Homma, S; Reed, JC; Takayama, S,期刊:Biochemical and Biophysical Research Communications, 页码:413-418 , 文章类型: Article,,卷期:2010年400-3]
- BAG3, a member of the Hsc70 binding co-chaperone BAG-family proteins, has critical roles in regulating actin organization, cell adhesion, cell motility and tumor metastasis. The PDZ domain containing guanine nucleotide e...
- Cyclin D-1 blocks the anti-proliferative function of RUNX3 by interfering with RUNX3-p300 interaction
[作者:Iwatani, K; Fujimoto, T; Ito, T,期刊:Biochemical and Biophysical Research Communications, 页码:426-431 , 文章类型: Article,,卷期:2010年400-3]
- Transcriptional function of cyclin D1, whose deregulation is frequently observed in human cancers, has been suggested to contribute to cancer formation In the present study, we show that cyclin D1 protein inhibits RUNX3 ...
|