- Evolution of the Schlafen genes, a gene family associated with embryonic lethality, meiotic drive, immune processes and orthopoxvirus virulence
[作者:Bustos, O; Naik, S; Ayers, G; Casola, C; Perez-Lamigueiro, MA; Chippindale, PT; Pritham, EJ; de la Casa-Esperon, E,期刊:Gene, 页码:1-11 , 文章类型: Article,,卷期:2009年447-1]
- Genes of the Schlafen family, first discovered in mouse, are expressed in hematopoietic cells and are involved in immune processes. Previous results showed that they are candidate genes for two major phenomena: meiotic d...
- Clinical variability and expression of the NBN c.657del5 allele in Nijmegen Breakage Syndrome
[作者:Lins, S; Kim, R; Kruger, L; Chrzanowska, KH; Seemanova, E; Digweed, M,期刊:Gene, 页码:12-17 , 文章类型: Article,,卷期:2009年447-1]
- Patients affected by the autosomal recessive Nijmegen Breakage Syndrome (NBS [MIM 251260]) have possibly the highest risk for developing a malignancy of all the chromosomal instability syndromes. This reflects the profou...
- Evolution of the RNA-dependent RNA polymerase (RdRP) genes: Duplications and possible losses before and after the divergence of major eukaryotic groups
[作者:Zong, J; Yao, X; Yin, JY; Zhang, DB; Ma, H,期刊:Gene, 页码:29-39 , 文章类型: Article,,卷期:2009年447-1]
- Eukaryotic RNA-dependent RNA polymerases (RdRPs, encoded by RDR genes) play critical roles in developmental regulation, maintenance of genome integrity, and defense against foreign nucleic acids. However, the phylogeneti...
- Molecular characterization and expression pattern of the equine lactate dehydrogenase A and B genes
[作者:Echigoya, Y; Sato, T; Itou, T; Endo, H; Sakai, T,期刊:Gene, 页码:40-50 , 文章类型: Article,,卷期:2009年447-1]
- The species-specific properties of LDH isozymes are essentially determined by M (muscle) and H (heart) subunit proteins encoded by the LDHA and LDHB genes, respectively. In the present study, we molecularly characterized...
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