- Inactivation of the vitamin D receptor in APC(min/+) mice reveals a critical role for the vitamin D receptor in intestinal tumor growth
[作者:Zheng, W; Wong, KE; Zhang, ZY; Dougherty, U; Mustafi, R; Kong, J; Deb, DK; Zheng, HC; Bissonnette, M; Li, YC,期刊:International Journal of Cancer, 页码:10-19 , 文章类型: Article,,卷期:2012年130-1]
- Emerging evidence supports an inhibitory role for vitamin D in colorectal carcinogenesis; however, the mechanism remains unclear. The adenomatous polyposis coli (APC)/beta-catenin pathway plays a critical role in colorec...
- Long-term clinical and immunological effects of p53-SLP (R) vaccine in patients with ovarian cancer
[作者:Leffers, N; Vermeij, R; Hoogeboom, BN; Schulze, UR; Wolf, R; Hamming, IE; van der Zee, AG; Melief, KJ; van der Burg, SH; Daemen, T; Nijman, HW,期刊:International Journal of Cancer, 页码:105-112 , 文章类型: Article,,卷期:2012年130-1]
- Vaccine-induced p53-specific immune responses were previously reported to be associated with improved response to secondary chemotherapy in patients with small cell lung cancer. We investigated long-term clinical and imm...
- Spectrin alpha II and beta II tetramers contribute to platinum anticancer drug resistance in ovarian serous adenocarcinoma
[作者:Maeda, O; Shibata, K; Hosono, S; Fujiwara, S; Kajiyama, H; Ino, K; Nawa, A; Tamakoshi, K; Kikkawa, F,期刊:International Journal of Cancer, 页码:113-121 , 文章类型: Article,,卷期:2012年130-1]
- To overcome drug resistance in ovarian carcinoma, novel resistance mechanisms must be elucidated for clinical application. We purified 2 proteins in the 300 kDa range from cisplatin-resistant cells (NOS2CR2) by affinity ...
- Tumor suppressor dual-specificity phosphatase 6 (DUSP6) impairs cell invasion and epithelial-mesenchymal transition (EMT)-associated phenotype
[作者:Wong, VCL; Chen, H; Ko, JMY; Chan, KW; Chan, YP; Law, S; Chua, D; Kwong, DLW; Lung, HL; Srivastava, G; Tang, JCO; Tsao, SW; Zabarovsky, ER; Stanbridge, EJ; Lung, ML,期刊:International Journal of Cancer, 页码:83-95 , 文章类型: Article,,卷期:2012年130-1]
- Suppressive effects of DUSP6 in tumorigenesis and EMT-associated properties were observed. Dual-specificity phosphatase (DUSP6) is a MAP kinase phosphatase (MKP) negatively regulating the activity of ERK, one of the majo...
- High expression of indoleamine 2,3-dioxygenase in the tumour is associated with medullary features and favourable outcome in basal-like breast carcinoma
[作者:Jacquemier, J; Bertucci, F; Finetti, P; Esterni, B; Charafe-Jauffret, E; Thibult, ML; Houvenaeghel, G; Van den Eynde, B; Birnbaum, D; Olive, D; Xerri, L,期刊:International Journal of Cancer, 页码:96-104 , 文章类型: Article,,卷期:2012年130-1]
- Medullary breast cancer (MBC) is a basal-like breast carcinoma (BLBC) with a favourable outcome, whereas nonmedullary BLBC has a poor prognosis. Tumour infiltrating lymphocytes (TILs) are present in both MBC and BLBC. We...
- Lower sensitivity of screening mammography after previous benign breast surgery
[作者:Smallenburg, VV; Duijm, LEM; Voogd, AC; Groenewoud, JH; Jansen, FH; van Beek, M; Louwman, MWJ,期刊:International Journal of Cancer, 页码:122-128 , 文章类型: Article,,卷期:2012年130-1]
- Few data are available on the effect of previous benign breast surgery on screening mammography accuracy. We determined whether sensitivity of screening mammography and tumor characteristics are different for women with ...
- Combining 33 genetic variants with prostate-specific antigen for prediction of prostate cancer: longitudinal study
[作者:Johansson, M; Holmstrom, B; Hinchliffe, SR; Bergh, A; Stenman, UH; Hallmans, G; Wiklund, F; Stattin, P,期刊:International Journal of Cancer, 页码:129-137 , 文章类型: Article,,卷期:2012年130-1]
- The aim of this study was to investigate if a genetic risk score including 33 common genetic variants improves prediction of prostate cancer when added to measures of prostate-specific antigen (PSA). We conducted a case-...
- Serum antiglycan antibody detection of nonmucinous ovarian cancers by using a printed glycan array
[作者:Jacob, F; Goldstein, DR; Bovin, NV; Pochechueva, T; Spengler, M; Caduff, R; Fink, D; Vuskovic, MI; Huflejt, ME; Heinzelmann-Schwarz, V,期刊:International Journal of Cancer, 页码:138-146 , 文章类型: Article,,卷期:2012年130-1]
- Epithelial ovarian cancer has the highest mortality rate among gynecological cancers. Altered glycosylation is associated with oncogenic transformation producing tumor-associated carbohydrate antigens. We investigated th...
- Intake of vegetables, fruits, carotenoids and vitamins C and E and pancreatic cancer risk in The Netherlands Cohort Study
[作者:Heinen, MM; Verhage, BAJ; Goldbohm, RA; van den Brandt, PA,期刊:International Journal of Cancer, 页码:147-158 , 文章类型: Article,,卷期:2012年130-1]
- Epidemiological data investigating the relation between fruit and vegetable consumption and pancreatic cancer risk have shown inconsistent results so far. Most case-control studies observed an inverse association with to...
- Sugars in diet and risk of cancer in the NIH-AARP Diet and Health Study
[作者:Tasevska, N; Jiao, L; Cross, AJ; Kipnis, V; Subar, AF; Hollenbeck, A; Schatzkin, A; Potischman, N,期刊:International Journal of Cancer, 页码:159-169 , 文章类型: Article,,卷期:2012年130-1]
- Prospective epidemiologic data on the effects of different types of dietary sugars on cancer incidence have been limited. In this report, we investigated the association of total sugars, sucrose, fructose, added sugars, ...
- Time trends and latitudinal differences in melanoma thickness distribution in Australia, 1990-2006
[作者:Baade, P; Meng, XQ; Youlden, D; Aitken, J; Youl, P,期刊:International Journal of Cancer, 页码:170-178 , 文章类型: Article,,卷期:2012年130-1]
- This study investigated time trends and latitude differentials in the thickness distributions of invasive melanomas diagnosed in Australia between 1990 and 2006 using data from population-based cancer registries. Trends ...
- Is birth weight associated with childhood lymphoma? A meta-analysis
[作者:Papadopoulou, C; Antonopoulos, CN; Sergentanis, TN; Panagopoulou, P; Belechri, M; Petridou, ET,期刊:International Journal of Cancer, 页码:179-189 , 文章类型: Article,,卷期:2012年130-1]
- Several risk factors have been identified for childhood lymphomas. The purpose of this meta-analysis was to synthesize current evidence regarding the association between birth weight with primarily the risk for non-Hodgk...
- Preclinical therapeutic response of residual metastatic disease is distinct from its primary tumor of origin
[作者:Day, CP; Carter, J; Bonomi, C; Hollingshead, M; Merlino, G,期刊:International Journal of Cancer, 页码:190-199 , 文章类型: Article,,卷期:2012年130-1]
- Cancer-related deaths are caused principally by recurrence and metastasis arising from residual disease, whose therapeutic responses has been suggested to be substantially different from primary tumors. However, experime...
- The activated transforming growth factor-beta signaling pathway in peritoneal metastases is a potential therapeutic target in ovarian cancer
[作者:Yamamura, S; Matsumura, N; Mandai, M; Huang, ZQ; Oura, T; Baba, T; Hamanishi, J; Yamaguchi, K; Kang, HS; Okamoto, T; Abiko, K; Mori, S; Murphy, SK; Konishi, I,期刊:International Journal of Cancer, 页码:20-28 , 文章类型: Article,,卷期:2012年130-1]
- Peritoneal dissemination including omental metastasis is the most frequent route of metastasis and an important prognostic factor in advanced ovarian cancer. We analyzed the publicly available microarray dataset (GSE2109...
- Galbanic acid decreases androgen receptor abundance and signaling and induces G(1) arrest in prostate cancer cells
[作者:Zhang, Y; Kim, KH; Zhang, W; Guo, YL; Kim, SH; Lu, JX,期刊:International Journal of Cancer, 页码:200-212 , 文章类型: Article,,卷期:2012年130-1]
- Androgen receptor (AR) signaling is crucial for the genesis and progression of prostate cancer (PCa). We compared the growth responses of AR(+) LNCaP and LNCaP C4-2 vs. AR(-) DU145 and PC-3 PCa cell lines to galbanic aci...
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