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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共74条记录   Decreased Expression of ARV1 Results in Cholesterol Retention in the Endoplasmic Reticulum and Abnormal Bile Acid Metabolism [作者：Tong, FM; Billheimer, J; Shechtman, CF; Liu, Y; Crooke, R; Graham, M; Cohen, DE; Sturley, SL; Rader, DJ,期刊：Journal of Biological Chemistry, 页码：33632-33641 , 文章类型： Article，,卷期：2010年285-44] Endoplasmic reticulum (ER) membrane cholesterol is maintained at an optimal concentration of similar to 5 mol % by the net impact of sterol synthesis, modification, and export. Arv1p was first identified in the yeast Sac... C331A Mutant of Neuronal Nitric-oxide Synthase Is Labilized for Hsp70/CHIP (C Terminus of HSC70-interacting Protein)-dependent Ubiquitination [作者：Clapp, KM; Peng, HM; Morishima, Y; Lau, M; Walker, VJ; Pratt, WB; Osawa, Y,期刊：Journal of Biological Chemistry, 页码：33642-33651 , 文章类型： Article，,卷期：2010年285-44] It is established that suicide inactivation of neuronal nitricoxide synthase (nNOS) by drugs and other xenobiotics leads to ubiquitination and proteasomal degradation of the enzyme. The exact mechanism is not known, alth... Expression of miR-33 from an SREBP2 Intron Inhibits Cholesterol Export and Fatty Acid Oxidation [作者：Gerin, I; Clerbaux, LA; Haumont, O; Lanthier, N; Das, AK; Burant, CF; Leclercq, IA; MacDougald, OA; Bommer, GT,期刊：Journal of Biological Chemistry, 页码：33652-33661 , 文章类型： Article，,卷期：2010年285-44] The regulation of synthesis, degradation, and distribution of lipids is crucial for homeostasis of organisms and cells. The sterol regulatory element-binding protein (SREBP) transcription factor family is post-translatio... ZEB1 Coordinately Regulates Laminin-332 and beta 4 Integrin Expression Altering the Invasive Phenotype of Prostate Cancer Cells [作者：Drake, JM; Barnes, JM; Madsen, JM; Domann, FE; Stipp, CS; Henry, MD,期刊：Journal of Biological Chemistry, 页码：33940-33948 , 文章类型： Article，,卷期：2010年285-44] Metastasis involves the invasion of cancer cells across both the extracellular matrix and cellular barriers, and an evolving theme is that epithelial-to-mesenchymal transition (EMT) may mediate invasive cellular behavior... Regulation of the AGS3 center dot G alpha(i) Signaling Complex by a Seven-transmembrane Span Receptor [作者：Oner, SS; An, NF; Vural, A; Breton, B; Bouvier, M; Blumer, JB; Lanier, SM,期刊：Journal of Biological Chemistry, 页码：33949-33958 , 文章类型： Article，,卷期：2010年285-44] G-protein signaling modulators (GPSM) play diverse functional roles through their interaction with G-protein subunits. AGS3 (GPSM1) contains four G-protein regulatory motifs (GPR) that directly bind G alpha(i) free of G ... Testicular Expression of Adora3i2 in Adora3 Knockout Mice Reveals a Role of Mouse A3Ri2 and Human A3Ri3 Adenosine Receptors in Sperm [作者：Burnett, LA; Blais, EM; Unadkat, JD; Hille, B; Tilley, SL; Babcock, DF,期刊：Journal of Biological Chemistry, 页码：33662-33670 , 文章类型： Article，,卷期：2010年285-44] Adenosine is a candidate modulator of sperm motility in the female reproductive tract that increases sperm flagellar beat frequency in vitro. Past work suggested that this acceleration may involve equilibrative (ENT) and... Leo1 Subunit of the Yeast Paf1 Complex Binds RNA and Contributes to Complex Recruitment [作者：Dermody, JL; Buratowski, S,期刊：Journal of Biological Chemistry, 页码：33671-33679 , 文章类型： Article，,卷期：2010年285-44] The Paf1 complex (Paf1C) affects RNA polymerase II transcription by coordinating co-transcriptional chromatin modifications and helping recruit mRNA 3' end processing factors. Paf1C cross-links to transcribed genes, but ... SIRT1 Deacetylates and Inhibits SREBP-1C Activity in Regulation of Hepatic Lipid Metabolism [作者：Ponugoti, B; Kim, DH; Xiao, Z; Smith, Z; Miao, J; Zang, MW; Wu, SY; Chiang, CM; Veenstra, TD; Kemper, JK,期刊：Journal of Biological Chemistry, 页码：33959-33970 , 文章类型： Article，,卷期：2010年285-44] The SIRT1 deacetylase inhibits fat synthesis and stimulates fat oxidation in response to fasting, but the underlying mechanisms remain unclear. Here we report that SREBP-1c, a key lipogenic activator, is an in vivo targe... A Processed Multidomain Mycoplasma hyopneumoniae Adhesin Binds Fibronectin, Plasminogen, and Swine Respiratory Cilia [作者：Seymour, LM; Deutscher, AT; Jenkins, C; Kuit, TA; Falconer, L; Minion, FC; Crossett, B; Padula, M; Dixon, NE; Djordjevic, SP; Walker, MJ,期刊：Journal of Biological Chemistry, 页码：33971-33978 , 文章类型： Article，,卷期：2010年285-44] Porcine enzootic pneumonia is a chronic respiratory disease that affects swine. The etiological agent of the disease, Mycoplasma hyopneumoniae, is a bacterium that adheres to cilia of the swine respiratory tract, resulti... Heart-specific Small Subunit of Myosin Light Chain Phosphatase Activates Rho-associated Kinase and Regulates Phosphorylation of Myosin Phosphatase Target Subunit 1 [作者：Shichi, D; Arimura, T; Ishikawa, T; Kimura, A,期刊：Journal of Biological Chemistry, 页码：33680-33690 , 文章类型： Article，,卷期：2010年285-44] Phosphorylation of myosin regulatory light chain (MLC) plays a regulatory role in muscle contraction, and the level of MLC phosphorylation is balanced by MLC kinase and MLC phosphatase (MLCP). MLCP consists of a catalyti... Ras Homolog Enriched in Brain (Rheb) Enhances Apoptotic Signaling [作者：Karassek, S; Berghaus, C; Schwarten, M; Goemans, CG; Ohse, N; Kock, G; Jockers, K; Neumann, S; Gottfried, S; Herrmann, C; Heumann, R; Stoll, R,期刊：Journal of Biological Chemistry, 页码：33979-33991 , 文章类型： Article，,卷期：2010年285-44] Rheb is a homolog of Ras GTPase that regulates cell growth, proliferation, and regeneration via mammalian target of rapamycin (mTOR). Because of the well established potential of activated Ras to promote survival, we sou... Structure of Rpn10 and Its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12 [作者：Riedinger, C; Boehringer, J; Trempe, JF; Lowe, ED; Brown, NR; Gehring, K; Noble, MEM; Gordon, C; Endicott, JA,期刊：Journal of Biological Chemistry, 页码：33992-34003 , 文章类型： Article，,卷期：2010年285-44] Schizosaccharomyces pombe Rpn10 (SpRpn10) is a proteasomal ubiquitin (Ub) receptor located within the 19 S regulatory particle where it binds to subunits of both the base and lid subparticles. We have solved the structur... Cathepsin X-deficient Gastric Epithelial Cells in Co-culture with Macrophages CHARACTERIZATION OF CYTOKINE RESPONSE AND MIGRATION CAPABILITY AFTER HELICOBACTER PYLORI INFECTION [作者：Bernhardt, A; Kuester, D; Roessner, A; Reinheckel, T; Krueger, S,期刊：Journal of Biological Chemistry, 页码：33691-33700 , 文章类型： Article，,卷期：2010年285-44] Our previous studies have shown an association between Helicobacter pylori infection, the strong up-regulation of cathepsin X (CTSX, also called cathepsin Z/P), and the development of gastric cancer. In the present study... Metabolism of Pentose Sugars in the Hyperthermophilic Archaea Sulfolobus solfataricus and Sulfolobus acidocaldarius [作者：Nunn, CEM; Johnsen, U; Schonheit, P; Fuhrer, T; Sauer, U; Hough, DW; Danson, MJ,期刊：Journal of Biological Chemistry, 页码：33701-33709 , 文章类型： Article，,卷期：2010年285-44] We have previously shown that the hyperthermophilic archaeon, Sulfolobus solfataricus, catabolizes D-glucose and D-galactose to pyruvate and glyceraldehyde via a non-phosphorylative version of the Entner-Doudoroff pathwa... Characterization of 5-Chloro-5-Deoxy-D-Ribose 1-Dehydrogenase in Chloroethylmalonyl Coenzyme A Biosynthesis SUBSTRATE AND REACTION PROFILING [作者：Kale, AJ; McGlinchey, RP; Moore, BS,期刊：Journal of Biological Chemistry, 页码：33710-33717 , 文章类型： Article，,卷期：2010年285-44] SalM is a short-chain dehydrogenase/reductase enzyme from the marine actinomycete Salinispora tropica that is involved in the biosynthesis of chloroethylmalonyl-CoA, a novel halogenated polyketide synthase extender un... Post-transcriptional Up-regulation of Tsc-22 by Ybx1, a Target of miR-216a, Mediates TGF-beta-induced Collagen Expression in Kidney Cells [作者：Kato, M; Wang, L; Putta, S; Wang, M; Yuan, H; Sun, GD; Lanting, L; Todorov, I; Rossi, JJ; Natarajan, R,期刊：Journal of Biological Chemistry, 页码：34004-34015 , 文章类型： Article，,卷期：2010年285-44] Increased accumulation of extracellular matrix proteins and hypertrophy induced by transforming growth factor-beta 1 (TGF-beta)in renal mesangial cells (MC) are hallmark features of diabetic nephropathy. Although the pos...