- Mast cells have a protumorigenic role in human thyroid cancer
[作者：Melillo, RM; Guarino, V; Avilla, E; Galdiero, MR; Liotti, F; Prevete, N; Rossi, FW; Basolo, F; Ugolini, C; de Paulis, A; Santoro, M; Marone, G,期刊：Oncogene, 页码：6203-6215 , 文章类型： Article，,卷期：2010年29-47]
- In different human carcinoma types, mast cell infiltrate increases with respect to normal tissue and mast cell density correlates with a bad prognosis. To assess the role of mast cells in human thyroid cancer, we compare...
- Rates of loss of heterozygosity and mitotic recombination in NF2 schwannomas, sporadic vestibular schwannomas and schwannomatosis schwannomas
[作者：Hadfield, KD; Smith, MJ; Urquhart, JE; Wallace, AJ; Bowers, NL; King, AT; Rutherford, SA; Trump, D; Newman, WG; Evans, DG,期刊：Oncogene, 页码：6216-6221 , 文章类型： Article，,卷期：2010年29-47]
- Biallelic inactivation of the NF2 gene occurs in the majority of schwannomas. This usually involves a combination of a point mutation or multiexon deletion, in conjunction with either a second point mutation or loss of h...
- Cooperative interactions of PTEN deficiency and RAS activation in melanoma metastasis
[作者：Nogueira, C; Kim, KH; Sung, H; Paraiso, KHT; Dannenberg, JH; Bosenberg, M; Chin, L; Kim, M,期刊：Oncogene, 页码：6222-6232 , 文章类型： Article，,卷期：2010年29-47]
- Mitogen-activated protein kinase (MAPK) and AKT pathways are frequently co-activated in melanoma through overexpression of receptor tyrosine kinases, mutations in their signaling surrogates, such as RAS and BRAF, or loss...
- Suppression of cell-cycle progression by Jun dimerization protein-2 (JDP2) involves downregulation of cyclin-A2
[作者：Pan, J; Nakade, K; Huang, YC; Zhu, ZW; Masuzaki, S; Hasegawa, H; Murata, T; Yoshiki, A; Yamaguchi, N; Lee, CH; Yang, WC; Tsai, EM; Obata, Y; Yokoyama, KK,期刊：Oncogene, 页码：6245-6256 , 文章类型： Article，,卷期：2010年29-47]
- We report here a novel role for Jun dimerization protein-2 (JDP2) as a regulator of the progression of normal cells through the cell cycle. To determine the role of JDP2 in vivo, we generated Jdp2-knockout (Jdp2KO) mice ...
- CIP2A mediates effects of bortezomib on phospho-Akt and apoptosis in hepatocellular carcinoma cells
[作者：Chen, KF; Liu, CY; Lin, YC; Yu, HC; Liu, TH; Hou, DR; Chen, PJ; Cheng, AL,期刊：Oncogene, 页码：6257-6266 , 文章类型： Article，,卷期：2010年29-47]
- Previously, we reported that Akt inactivation determines the sensitivity of hepatocellular carcinoma (HCC) cells to bortezomib. In this study, we report that cancerous inhibitor of protein phosphatase 2A (CIP2A), a cellu...
- PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy
[作者：Salvati, E; Scarsella, M; Porru, M; Rizzo, A; Iachettini, S; Tentori, L; Graziani, G; D'Incalci, M; Stevens, MFG; Orlandi, A; Passeri, D; Gilson, E; Zupi, G; Leonetti, C; Biroccio, A,期刊：Oncogene, 页码：6280-6293 , 文章类型： Article，,卷期：2010年29-47]
- New anti-telomere strategies represent important goals for the development of selective cancer therapies. In this study, we reported that uncapped telomeres, resulting from pharmacological stabilization of quadruplex DNA...
- The expression of activated Y-box binding protein-1 serine 102 mediates trastuzumab resistance in breast cancer cells by increasing CD44(+) cells
[作者：Dhillon, J; Astanehe, A; Lee, C; Fotovati, A; Hu, K; Dunn, SE,期刊：Oncogene, 页码：6294-6300 , 文章类型： Article，,卷期：2010年29-47]
- The development of acquired resistance to trastuzumab remains a prevalent challenge in the treatment of patients whose tumors express human epidermal growth factor 2 (HER2). We previously reported that HER2 overexpressin...
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