- Histone onco-modifications
[作者:Fullgrabe, J; Kavanagh, E; Joseph, B,期刊:Oncogene, 页码:3391-3403 , 文章类型: Review,,卷期:2011年30-31]
- Post-translational modification of histones provides an important regulatory platform for processes such as gene expression, DNA replication and repair, chromosome condensation and segregation and apoptosis. Disruption o...
- Methylation of an intronic region regulates miR-199a in testicular tumor malignancy
[作者:Cheung, HH; Davis, AJ; Lee, TL; Pang, AL; Nagrani, S; Rennert, OM; Chan, WY,期刊:Oncogene, 页码:3404-3415 , 文章类型: Article,,卷期:2011年30-31]
- In the testicular cancer cell line, NT2, we previously demonstrated that differentially methylated regions were located in introns or intergenic regions, and postulated these might regulate non-coding RNAs. Three microRN...
- MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia
[作者:Gao, XN; Lin, J; Li, YH; Gao, L; Wang, XR; Wang, W; Kang, HY; Yan, GT; Wang, LL; Yu, L,期刊:Oncogene, 页码:3416-3428 , 文章类型: Article,,卷期:2011年30-31]
- Aberrant activation of c-kit proto-oncogene contributes to abnormal cell proliferation by altering the tyrosine kinase signaling and constitutes a crucial impetus for leukemo-genesis. Epigenetic silencing of tumor-suppre...
- Imbalance of Clara cell-mediated homeostatic inflammation is involved in lung metastasis
[作者:Tomita, T; Sakurai, Y; Ishibashi, S; Maru, Y,期刊:Oncogene, 页码:3429-3439 , 文章类型: Article,,卷期:2011年30-31]
- We have previously shown that tumor necrosis factor (TNF)alpha produced from primary tumor-induced expression of two endogenous Toll-like receptor 4 (TLR4) ligands, S100A8 and serum amyloid A3 (SAA3), in pre-metastatic l...
- miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT
[作者:Xiang, X; Zhuang, X; Ju, S; Zhang, S; Jiang, H; Mu, J; Zhang, L; Miller, D; Grizzle, W; Zhang, HG,期刊:Oncogene, 页码:3440-3453 , 文章类型: Article,,卷期:2011年30-31]
- A micro-RNA, miR-155, is overexpressed in many types of cancer cells, including breast cancer, and its role(s) in tumor metastasis has been studied on a very limited basis. Tumor metastasis is a multi-step process with t...
- Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition
[作者:Ying, M; Wang, S; Sang, Y; Sun, P; Lal, B; Goodwin, CR; Guerrero-Cazares, H; Quinones-Hinojosa, A; Laterra, J; Xia, S,期刊:Oncogene, 页码:3454-3467 , 文章类型: Article,,卷期:2011年30-31]
- It is necessary to understand mechanisms by which differentiating agents influence tumor-initiating cancer stem cells. Toward this end, we investigated the cellular and molecular responses of glioblastoma stem-like cells...
- Ep-CAM is a significant prognostic factor in pancreatic cancer patients by suppressing cell activity
[作者:Akita, H; Nagano, H; Takeda, Y; Eguchi, H; Wada, H; Kobayashi, S; Marubashi, S; Tanemura, M; Takahashi, H; Ohigashi, H; Tomita, Y; Ishikawa, O; Mori, M; Doki, Y,期刊:Oncogene, 页码:3468-3476 , 文章类型: Article,,卷期:2011年30-31]
- The identification of molecular markers useful for predicting prognosis in pancreatic cancer patients is crucial for advances in disease management. The epithelial cell adhesion molecule (Ep-CAM) is known to express in m...
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