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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共7条记录   Sumoylation of MEL1S at lysine 568 and its interaction with CtBP facilitates its repressor activity and the blockade of G-CSF-induced myeloid differentiation [作者：Nishikata, I; Nakahata, S; Saito, Y; Kaneda, K; Ichihara, E; Yamakawa, N; Morishita, K,期刊：Oncogene, 页码：4194-4207 , 文章类型： Article，,卷期：2011年30-40] MEL1 (MDS1/EVI1-like gene 1/PRDM16), which was identified as a gene near the chromosomal breakpoint in t(1;3)(p36;q21)-positive human acute myeloid leukemia cells, belongs to the (P) under bar RDI-BF1-(R) under bar IZ1 h... Oligomeric peroxiredoxin-I is an essential intermediate for p53 to activate MST1 kinase and apoptosis [作者：Morinaka, A; Funato, Y; Uesugi, K; Miki, H,期刊：Oncogene, 页码：4208-4218 , 文章类型： Article，,卷期：2011年30-40] Mammalian Ste20-like kinase-1 (MST1) kinase mediates H(2)O(2)-induced cell death by anticancer drugs such as cisplatin in a p53-dependent manner. However, the mechanism underlying MST1 activation by H(2)O(2) remains unkn... Molecular imaging of tumor metabolism and apoptosis [作者：Haberkorn, U; Markert, A; Mier, W; Askoxylakis, V; Altmann, A,期刊：Oncogene, 页码：4141-4151 , 文章类型： Review，,卷期：2011年30-40] Increased metabolism in a number of cellular pathways is a common feature of malignant tumors. This metabolic hallmark of neoplastic tissue led to the development of radiopharmaceuticals for the assessment of transport a... MSX2 is an oncogenic downstream target of activated WNT signaling in ovarian endometrioid adenocarcinoma [作者：Zhai, Y; Iura, A; Yeasmin, S; Wiese, AB; Wu, R; Feng, Y; Fearon, ER; Cho, KR,期刊：Oncogene, 页码：4152-4162 , 文章类型： Article，,卷期：2011年30-40] Ovarian endometrioid adenocarcinomas (OEAs) frequently exhibit constitutive activation of canonical WNT signaling, usually as a result of oncogenic mutations that stabilize and dysregulate the beta-catenin protein. In pr... Phosphoproteomic mass spectrometry profiling links Src family kinases to escape from HER2 tyrosine kinase inhibition [作者：Rexer, BN; Ham, AJL; Rinehart, C; Hill, S; Granja-Ingram, ND; Gonzalez-Angulo, AM; Mills, GB; Dave, B; Chang, JC; Liebler, DC; Arteaga, CL,期刊：Oncogene, 页码：4163-4174 , 文章类型： Article，,卷期：2011年30-40] Despite the initial effectiveness of the tyrosine kinase inhibitor lapatinib against HER2 gene-amplified breast cancers, most patients eventually relapse after treatment, implying that tumors acquire mechanisms of drug r... Molecular targeting of CSN5 in human hepatocellular carcinoma: a mechanism of therapeutic response [作者：Lee, YH; Judge, AD; Seo, D; Kitade, M; Gomez-Quiroz, LE; Ishikawa, T; Andersen, JB; Kim, BK; Marquardt, JU; Raggi, C; Avital, I; Conner, EA; MacLachlan, I; Factor, VM; Thorgeirsson, SS,期刊：Oncogene, 页码：4175-4184 , 文章类型： Article，,卷期：2011年30-40] Development of targeted therapy for hepatocellular carcinoma (HCC) remains a major challenge. We have recently identified an elevated expression of the fifth subunit of COP9 signalosome (CSN5) in early HCC as compared wi... LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms [作者：King, CE; Wang, L; Winograd, R; Madison, BB; Mongroo, PS; Johnstone, CN; Rustgi, AK,期刊：Oncogene, 页码：4185-4193 , 文章类型： Article，,卷期：2011年30-40] Lin28b is an RNA-binding protein that inhibits biogenesis of let-7 microRNAs. LIN28B is overexpressed in diverse cancers, yet a specific role in the molecular pathogenesis of colon cancer has to be elucidated. We have de...