- Control of tumor and microenvironment cross-talk by miR-15a and miR-16 in prostate cancer
[作者：Musumeci, M; Coppola, V; Addario, A; Patrizii, M; Maugeri-Sacca, M; Memeo, L; Colarossi, C; Francescangeli, F; Biffoni, M; Collura, D; Giacobbe, A; D'Urso, L; Falchi, M; Venneri, MA; Muto, G; De Maria, R; Bonci, D,期刊：Oncogene, 页码：4231-4242 , 文章类型： Article，,卷期：2011年30-41]
- The interaction between cancer cells and microenvironment has a critical role in tumor development and progression. Although microRNAs regulate all the major biological mechanisms, their influence on tumor microenvironme...
- Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours
[作者：Rajan, N; Elliott, R; Clewes, O; Mackay, A; Reis-Filho, JS; Burn, J; Langtry, J; Sieber-Blum, M; Lord, CJ; Ashworth, A,期刊：Oncogene, 页码：4243-4260 , 文章类型： Article，,卷期：2011年30-41]
- Individuals with germline mutations in the tumour-suppressor gene CYLD are at high risk of developing disfiguring cutaneous appendageal tumours, the defining tumour being the highly organised cylindroma. Here, we analyse...
- P73 regulates cisplatin-induced apoptosis in ovarian cancer cells via a calcium/calpain-dependent mechanism
[作者：Al-Bahlani, S; Fraser, M; Wong, AYC; Sayan, BS; Bergeron, R; Melino, G; Tsang, BK,期刊：Oncogene, 页码：4219-4230 , 文章类型： Article，,卷期：2011年30-41]
- P73 is important in drug-induced apoptosis in some cancer cells, yet its role in the regulation of chemosensitivity in ovarian cancer (OVCA) is poorly understood. Furthermore, if and how the deregulation of p73-mediated ...
- Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional
[作者：Lossaint, G; Besnard, E; Fisher, D; Piette, J; Dulic, V,期刊：Oncogene, 页码：4261-4274 , 文章类型： Article，,卷期：2011年30-41]
- In the presence of sustained DNA damage occurring in S-phase or G2, normal cells arrest before mitosis and eventually become senescent. The checkpoint kinases Chk1/Chk2 and the CDK inhibitor p21 are known to have importa...
- CEACAM1 creates a pro-angiogenic tumor microenvironment that supports tumor vessel maturation
[作者：Gerstel, D; Wegwitz, F; Jannasch, K; Ludewig, P; Scheike, K; Alves, F; Beauchemin, N; Deppert, W; Wagener, C; Horst, AK,期刊：Oncogene, 页码：4275-4288 , 文章类型： Article，,卷期：2011年30-41]
- We have studied the effects of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) on tumor angiogenesis in murine ductal mammary adenocarcinomas. We crossed transgenic mice with whey acidic protein promo...
- Shared acquired genomic changes in zebrafish and human T-ALL
[作者：Rudner, LA; Brown, KH; Dobrinski, KP; Bradley, DF; Garcia, MI; Smith, ACH; Downie, JM; Meeker, ND; Look, AT; Downing, JR; Gutierrez, A; Mullighan, CG; Schiffman, JD; Lee, C; Trede, NS; Frazer, JK,期刊：Oncogene, 页码：4289-4296 , 文章类型： Article，,卷期：2011年30-41]
- T-cell acute lymphoblastic leukemia (T-ALL) is a challenging clinical entity with high rates of induction failure and relapse. To discover the genetic changes occurring in T-ALL, and those contributing to relapse, we stu...
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