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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共7条记录   Nonprofit Organizations and Pharmaceutical Research and Development [作者：Moos, WH; Mirsalis, JC,期刊：Drug Development Research, 页码：461-471 , 文章类型： Article，,卷期：2009年70-7] Not-for-profit or nonprofit organizations (NPOs) are playing an increasingly important role in providing solutions to the significant challenges faced by both large pharmaceutical and smaller biotechnology companies in t... The Brain Angiotensin IV/AT(4) Receptor System as a New Target for the Treatment of Alzheimer's Disease [作者：Wright, JW; Harding, JW,期刊：Drug Development Research, 页码：472-480 , 文章类型： Article，,卷期：2009年70-7] The brain renin-angiotensin system (RAS) regulates several physiologies including blood pressure, body sodium and water balance, cyclicity of reproductive hormones and related sexual behaviors, and the release of pituita... Cathelicidin Peptide SMAP-29: Comprehensive Review of its Properties and Potential as a Novel Class of Antibiotics [作者：Dawson, RM; Liu, CQ,期刊：Drug Development Research, 页码：481-498 , 文章类型： Article，,卷期：2009年70-7] Sheep myeloid antimicrobial peptide of 29 amino acids (SMAP-29) is one of the most potent antimicrobial peptides known, with a broad spectrum of activity against bacteria, fungi, and viruses. It has also been shown to pr... Preparation of Carboxy-PEG-PLA Nanoparticles Loaded With Camptothecin and Their Body Distribution in Solid Tumor-Bearing Mice [作者：Ueki, K; Onishi, H; Sasatsu, M; Machida, Y,期刊：Drug Development Research, 页码：512-519 , 文章类型： Article，,卷期：2009年70-7] Carboxy-polyethylene glycol-poly(DL-lactic acid) block copolymer was synthesized by reductive amination of carboxy-polyethylene glycol-amine and aldehyde-ended poly(DL-lactic acid). The obtained product, PA-PEG-CB, compo... Diclofenac Acid: A Free-Radical-Scavenger to Protect DNA Against Radical-Induced Oxidation [作者：Tang, YZ; Liu, ZQ,期刊：Drug Development Research, 页码：520-524 , 文章类型： Article，,卷期：2009年70-7] The present work focused on the antioxidant effects of diclofenac acid (DaH) and its sodium salt (DaNaH) on the radical-induced oxidation of DNA. 2,2'-Azobis(2-amidinopropane) dihydrochloride (AAPH) was used as radical i... Bright Lights, Clearly Visible in the Healthcare R&D Tunnel, Could Burn Out for Lack of Funds [作者：Moos, WH; Rurka, JE; Miller, SM,期刊：Drug Development Research, 页码：457-460 , 文章类型： Editorial Material，,卷期：2009年70-7] Bright lights have never been more visible in healthcare R&D, each heralding innovative approaches to disease diagnosis, treatment, or prevention. Unfortunately, this promise of continued healthcare innovation is increas... Lactic Acid in Cancer and Mitochondrial Disease [作者：Steliou, K; Perrine, SP; Faller, DV,期刊：Drug Development Research, 页码：499-511 , 文章类型： Review，,卷期：2009年70-7] Cancer and the mitochondrial diseases are disparate disorders that have in common a failure of normal cellular respiratory activity in disease-affected tissues. In mitochondrial diseases, the impairment in the mitochondr...