- Low serum PON1 activity: An independent risk factor for coronary artery disease in North-West Indian type 2 diabetics
[作者:Gupta, N; Binu, KBK; Singh, S; Maturu, NV; Sharma, YP; Bhansali, A; Gill, KD,期刊:Gene, 页码:13-19 , 文章类型: Article,,卷期:2012年498-1]
- The paraoxonase (PON1) gene polymorphisms are known to affect the PON1 activity and coronary artery disease (CAD) risk. Studies done so far have given conflicting results. In the present study, we determined the role of ...
- Fractal genome sequences
[作者:Albrecht-Buehler, G,期刊:Gene, 页码:20-27 , 文章类型: Article,,卷期:2012年498-1]
- The existence of fractal sets of DNA sequences have long been suspected on the basis of statistical analyses of genome data. In this article we identify for the first time explicitly the GA-sequences as a class of fracta...
- 3-Hydroxy-3-methylglutaryl coenzyme A reductase 1 (HMG1) is highly associated with the cell division during the early stage of fruit development which determines the final fruit size in Litchi chinensis
[作者:Xia, R; Li, CQ; Lu, WJ; Du, J; Wang, ZH; Li, JG,期刊:Gene, 页码:28-35 , 文章类型: Article,,卷期:2012年498-1]
- 3-Hydroxy-3-methylglutaryl coenzyme A reductase (HMGR. EC: 1.1.1.34), an enzyme catalyzing the first committed step in the mevalonic acid (MVA) pathway for the biosynthesis of isoprenoids, has been reported to be involve...
- Microarray identification of conserved microRNAs in Pinellia pedatisecta
[作者:Wang, B; Dong, M; Chen, WD; Liu, XF; Feng, RJ; Xu, T,期刊:Gene, 页码:36-40 , 文章类型: Article,,卷期:2012年498-1]
- Large numbers of microRNAs (miRNAs) reportedly play important roles in plant development. However, none has been reported in Pinellia pedatisecta, an important aroid medicinal plant that possesses the only pedate leaf bl...
- Heat-shock-mediated elimination of the nptII marker gene in transgenic apple (Malus x domestica Borkh.)
[作者:Herzog, K; Flachowsky, H; Deising, HB; Hanke, MV,期刊:Gene, 页码:41-49 , 文章类型: Article,,卷期:2012年498-1]
- Production of marker-free genetically modified (GM) plants is one of the major challenges of molecular fruit breeding. Employing clean vector technologies, allowing the removal of undesired DNA sequences from GM plants, ...
- High levels of Paleolithic Y-chromosome lineages characterize Serbia
[作者:Regueiro, M; Rivera, L; Damnjanovic, T; Lukovic, L; Milasin, J; Herrera, RJ,期刊:Gene, 页码:59-67 , 文章类型: Article,,卷期:2012年498-1]
- Whether present-day European genetic variation and its distribution patterns can be attributed primarily to the initial peopling of Europe by anatomically modern humans during the Paleolithic, or to latter Near Eastern N...
- Clinical and biological significance of Cdk10 in hepatocellular carcinoma
[作者:Zhong, XY; Xu, XX; Yu, JH; Jiang, GX; Yu, Y; Tai, S; Wang, ZD; Cui, YF,期刊:Gene, 页码:68-74 , 文章类型: Article,,卷期:2012年498-1]
- Cyclin-dependent kinase 10 (Cdk10) is a Cdc2-related kinase and plays an essential role in the progression from the G2 to M phase of the cell cycle. However, relative little is known about its expression pattern, clinica...
- nMETR: Technique for facile recovery of hypomethylation genomic tags
[作者:Baskaev, K; Garazha, A; Gaifullin, N; Suntsova, MV; Zabolotneva, AA; Buzdin, AA,期刊:Gene, 页码:75-80 , 文章类型: Article,,卷期:2012年498-1]
- Genome-wide methylation studies frequently lack adequate controls to estimate proportions of background reads in the resulting datasets. To generate appropriate control pools, we developed technique termed nMETR (non-met...
- Molecular characterization and expression analysis of three hypoxia-inducible factor alpha subunits, HIF-1 alpha/2 alpha/3 alpha of the hypoxia-sensitive freshwater species, Chinese sucker
[作者:Chen, N; Chen, LP; Zhang, J; Chen, C; Wei, XL; Gul, Y; Wang, WM; Wang, HL,期刊:Gene, 页码:81-90 , 文章类型: Article,,卷期:2012年498-1]
- Hypoxia-inducible factors (HIFs) are transcription factors that respond to changes in oxygen tension in the cellular environment. In this study, we identified full-length cDNAs of HIF-1 alpha, HIF-2 alpha and HIF-3 alpha...
- Aberrant expression of Fc gamma RIIIA (CD16) contributes to the development of atherosclerosis
[作者:Huang, Y; Yin, HJ; Wang, JS; Liu, Q; Wu, CF; Chen, KJ,期刊:Gene, 页码:91-95 , 文章类型: Article,,卷期:2012年498-1]
- Previous studies have documented that Fc receptor III A of immunoglobulin G (Fc gamma RIIIA, also named CD16) is involved in the development of coronary heart disease (CHD). However, the mechanism responsible for Fc gamm...
- Novel mutation in the FOXC2 gene in three generations of a family with lymphoedema-distichiasis syndrome
[作者:Sutkowska, E; Gil, J; Stembalska, A; Hill-Bator, A; Szuba, A,期刊:Gene, 页码:96-99 , 文章类型: Article,,卷期:2012年498-1]
- Lymphoedema-distichiasis syndrome (LDS, OMIM #153400) is a genetic disorder with an autosomal dominant pattern of inheritance caused by mutations in the FOXC2 gene. Affected individuals typically present with lower extre...
- The dual behavior of heat shock protein 70 and asymmetric dimethylarginine in relation to serum CRP levels in type 2 diabetes
[作者:Nakhjavani, M; Morteza, A; Asgarani, F; Khalilzadeh, O; Ghazizadeh, Z; Bathaie, SZ; Esteghamati, A,期刊:Gene, 页码:107-111 , 文章类型: Article,,卷期:2012年498-1]
- Background: Experimental evidence suggests that heat shock proteins (HSP) and asymmetric dimethylarginine (ADMA) are induced in the state of chronic inflammation and stress conditions. They are both inhibitors of nitric ...
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