- Transport mechanisms of mmePEG(750)P(CL-co-TMC) polymeric micelles across the intestinal barrier
[作者:Mathot, F; Rieux, AD; Arien, A; Schneider, YJ; Brewster, M; Preat, V,期刊:Journal of controlled release, 页码:134-143 , 文章类型: Article,,卷期:2007年124-3]
- Monomethylether poly(ethyleneglycol)7(50)-Poly(caprolactone-co-trimethylene carbonate) (mnnePEG(750)P(CL-co-TMC) which spontaneously form micelles, can cross lipid bilayers via passive diffusion and demonstrate an oral b...
- Photo sensitiser-loaded biodegradable polymeric micelles: Preparation, characterisation and in vitro PDT efficacy
[作者:Rijcken, CJF; Hofinan, JW; van Zeeland, F; Hennink, WE; Van Nostrum, CF,期刊:Journal of controlled release, 页码:144-153 , 文章类型: Article,,卷期:2007年124-3]
- The application of photosensitisers (PSs) in photodynamic therapy (PDT) is often hampered by their hydrophobicity, as this complicates their formulation and results in an unfavourable biodistribution. Consequently, there...
- Zero-order therapeutic release from imprinted hydrogel contact lenses within in vitro physiological ocular tear flow
[作者:Ali, M; Horikawa, S; Venkatesh, S; Saha, J; Hong, JW; Byrne, ME,期刊:Journal of controlled release, 页码:154-162 , 文章类型: Article,,卷期:2007年124-3]
- Zero-order or concentration independent release kinetics are highly desirable from drug delivery devices. In this paper we demonstrate experimentally, for the first time, zero-order release of a small molecular weight th...
- Dendrimer/DNA complexes encapsulated in a water soluble polymer and supported on fast degrading star poly(DL-lactide) for localized gene delivery
[作者:Fu, HL; Cheng, SX; Zhang, XZ; Zhuo, RX,期刊:Journal of controlled release, 页码:181-188 , 文章类型: Article,,卷期:2007年124-3]
- Polyamidoamine (PAMAM) dendrimer/DNA complexes encapsulated in a water soluble polymer, poly-alpha,beta-[N-(2-hydroxyethyl)-L-aspartamide], were supported on a cholic acid functionalized star poly(DL-lactide) film with a...
- Corneal gene therapy
[作者:Klausner, EA; Peer, D; Chapman, RL; Multack, RF; Andurkar, SV,期刊:Journal of controlled release, 页码:107-133 , 文章类型: Review,,卷期:2007年124-3]
- Gene therapy to the cornea can potentially correct inherited and acquired diseases of the cornea. Factors that facilitate corneal gene delivery are the accessibility and transparency of the cornea, its stability ex vivo ...
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