- Broad Selective Efficacy of rMETase and PEG-rMETase on Cancer Cells In Vitro
[作者：Tan, YY; Xu, MX; Hoffman, RM,期刊：Anticancer Research, 页码：793-798 , 文章类型： Article，,卷期：2010年30-3]
- The elevated dependence on methionine of tumor cells is a cancer-specific metabolic defect. In current studies, the recombinant L-methionine alpha,gamma-lyase (rMETase), an Lmethionine depleting enzyme cloned from Pseudo...
- Rapamycin-mediated FOXO1 Inactivation Reduces the Anticancer Efficacy of Rapamycin
[作者：Abdelnour-Berchtold, E; Cerantola, Y; Roulin, D; Dormond-Meuwly, A; Demartines, N; Dormond, O,期刊：Anticancer Research, 页码：799-804 , 文章类型： Article，,卷期：2010年30-3]
- Background: Mammalian target of rapamycin (mTOR) inhibitors such as rapamycin have shown modest effects in cancer therapy due in part to the removal of a negative feedback loop leading to the activation of the phosphatid...
- Constituents of Carpobrotus edulis Inhibit P-Glycoprotein of MDR1-transfected Mouse Lymphoma Cells
[作者：Martins, A; Vasas, A; Schelz, ZS; Viveiros, M; Molnar, J; Hohmann, J; Amaral, L,期刊：Anticancer Research, 页码：829-835 , 文章类型： Article，,卷期：2010年30-3]
- A bioassay-guided separation protocol, including the testing of the extracts, fractions and pure compounds for their ability to inhibit P-glycoprotein (the efflux pump responsible for the multidrug resistance of the used...
- Calcium Glucarate Inhibits DMBA-induced Oral Carcinogenesis in the Hamster: Histomorphometric Evaluation
[作者：Lajolo, C; Sgambato, A; Maiorano, E; Lucchese, A; Capodiferro, S; Favia, G; Giuliani, M,期刊：Anticancer Research, 页码：843-849 , 文章类型： Article，,卷期：2010年30-3]
- Background: Calcium glucarate (CGT) is a promising chemopreventive agent. This study evaluated the in vivo efficacy of CGT in preventing 7,12-dimethylbenz(alpha) anthracene (DMBA)-induced oral carcinogenesis in the hamst...
- Significance of Karyopherin-alpha 2 (KPNA2) Expression in Esophageal Squamous Cell Carcinoma
[作者：Sakai, M; Sohda, M; Miyazaki, T; Suzuki, S; Sano, A; Tanaka, N; Inose, T; Nakajima, M; Kato, H; Kuwano, H,期刊：Anticancer Research, 页码：851-856 , 文章类型： Article，,卷期：2010年30-3]
- Background: Karyopherin-alpha 2 (KPNA2) is a member of the importin a family and has recently been reported to play an important role in tumorigenesis and tumor progression. The aim of the current study was to elucidate ...
- Phellodendron amurense Bark Extract Prevents Progression of Prostate Tumors in Transgenic Adenocarcinoma of Mouse Prostate: Potential for Prostate Cancer Management
[作者：Ghosh, R; Graham, H; Rivas, P; Tan, XJ; Crosby, K; Bhaskaran, S; Schoolfield, J; Banu, J; Fernandes, G; Yeh, IT; Kumar, AP,期刊：Anticancer Research, 页码：857-865 , 文章类型： Article，,卷期：2010年30-3]
- Prostate cancer is the second leading cause of cancer-related deaths in men in Western society. Epidemiological studies suggest that a reduced risk of cancer is associated with the consumption of a phytochemical-rich die...
- Thiochroman Derivative CH4986399, A New Nonsteroidal Estrogen Receptor Down-regulator, Is Effective in Breast Cancer Models
[作者：Yoneya, T; Taniguchi, K; Nakamura, R; Tsunenari, T; Ohizumi, I; Kanbe, Y; Morikawa, K; Kaiho, SI; Yamada-Okabe, H,期刊：Anticancer Research, 页码：873-878 , 文章类型： Article，,卷期：2010年30-3]
- Background: Tamoxifen, a selective estrogen receptor modulator, and fulvestrant, a selective estrogen receptor down-regulator (SERD), are now available for estrogen receptor-positive breast cancer patients. However, thes...
- MG132, A Proteasome Inhibitor, Induced Death of Calf Pulmonary Artery Endothelial Cells via Caspase-dependent Apoptosis and GSH Depletion
[作者：Han, YH; Moon, HJ; You, BR; Yang, YM; Kim, SZ; Kim, SH; Park, WH,期刊：Anticancer Research, 页码：879-885 , 文章类型： Article，,卷期：2010年30-3]
MG132, a proteasome inhibitor, has been shown to induce apoptotic cell death through formation of reactive oxygen species (ROS). Here, we evaluated the effects of MG132 on the growth of endothelial cells, especially c...
- LGP1, A Histone Deacetylase Inhibitor Analogue of FR235222, Sensitizes Promyelocytic Leukaemia U937 Cells to TRAIL-mediated Apoptosis
[作者：D'Acunto, CW; Carratu, A; Rodriquez, M; Taddei, M; Parente, L; Petrella, A,期刊：Anticancer Research, 页码：887-894 , 文章类型： Article，,卷期：2010年30-3]
Background: It has been shown that chemotherapeutic agents, such as histone deacetylase inhibitors (HDACi), are able to increase TRAIL-induced apoptosis in many types of cancer. In the present study, we investigated t...
- Yeast-based Identification of Prostate Tumor Antigens Provides an Effective Vaccine Platform
[作者：Jung, V; Fischer, E; Imig, J; Kleber, S; Nuber, N; Reinshagen, F; Kamradt, J; Grobholz, R; Knuth, A; Renner, C; Wadle, A,期刊：Anticancer Research, 页码：895-902 , 文章类型： Article，,卷期：2010年30-3]
- Background/Aim: To evaluate cancer/testis (CT) antigens as targets for immunotherapy or vaccine approaches in prostate cancer. Patients and Methods: We investigated the antibody response in 181 patients with prostate can...
- Water-soluble Taxol Conjugates with Dextran and Targets Tumor Cells by Folic Acid Immobilization
[作者：Nakamura, J; Nakajima, N; Matsumura, K; Hyon, SH,期刊：Anticancer Research, 页码：903-909 , 文章类型： Article，,卷期：2010年30-3]
- Background: Paclitaxel (taxol) is a very effective anticancer drug. However, the solution used to enhance the water solubility of paclitaxel, a mixture of polyoxyethylene castor oil (Cremphor EL) and dehydrated ethanol, ...
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