- Cannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma
[作者:Shi, Y; Zou, M; Baitei, EY; Alzahrani, AS; Parhar, RS; Al-Makhalafi, Z; Al-Mohanna, FA,期刊:Cancer gene therapy, 页码:101-107 , 文章类型: Article,,卷期:2008年15-2]
- Anaplastic thyroid carcinoma is the most aggressive type of thyroid malignancies. Previously, we demonstrated that tumorigenicity of anaplastic thyroid carcinoma cell line ARO was significantly reduced following interleu...
- Oncolytic virotherapy for ovarian carcinomatosis using a replication-selective vaccinia virus armed with a yeast cytosine deaminase gene
[作者:Chalikonda, S; Kivlen, MH; O'Malley, ME; Dong, XD; McCart, JA; Gorry, MC; Yin, XY; Brown, CK; Zeh, HJ; Guo, Z; Bartlett, DL,期刊:Cancer gene therapy, 页码:115-125 , 文章类型: Article,,卷期:2008年15-2]
- In this study, we assessed the ability of a highly tumor-selective oncolytic vaccinia virus armed with a yeast cytosine deaminase gene to infect and lyse human and murine ovarian tumors both in vitro and in vivo. The vir...
- Cell studies of a three-component antisense MORF/tat/Herceptin nanoparticle designed for improved tumor delivery
[作者:Liu, X; Wang, Y; Nakamura, K; Kubo, A; Hnatowich, DJ,期刊:Cancer gene therapy, 页码:126-132 , 文章类型: Article,,卷期:2008年15-2]
- The three-component nanoparticle of this investigation consisted of an anti-type I regulatory subunit a of the cyclic AMP-dependent protein kinase A (RI alpha) antisense phosphorodiamidate morpholino (MORF) oligomer, a t...
- Treatment of pulmonary metastatic tumors in mice using lentiviral vector-engineered stem cells
[作者:Zhang, X; Zhao, P; Kennedy, C; Chen, K; Wiegand, J; Washington, G; Marrero, L; Cui, Y,期刊:Cancer gene therapy, 页码:73-84 , 文章类型: Article,,卷期:2008年15-2]
- Active cancer immunotherapy relies on functional tumor-specific effector T lymphocytes for tumor elimination. Dendritic cells (DCs), as most potent antigen-presenting cells, have been popularly employed in clinical and e...
- Cancer immunotherapy based on recombinant Salmonella enterica serovar Typhimurium aroA strains secreting prostate-specific antigen and cholera toxin subunit B
[作者:Fensterle, J; Bergmann, B; Yone, CLRP; Hotz, C; Meyer, SR; Spreng, S; Goebel, W; Rapp, UR; Gentschev, I,期刊:Cancer gene therapy, 页码:85-93 , 文章类型: Article,,卷期:2008年15-2]
- Prostate cancer is the most common malignant tumor in men and is normally associated with increased serum levels of prostate-specific antigen (PSA). Therefore, PSA is one potential target for a prostate cancer vaccine. I...
- Tumor targeting carboxylesterase fused with anti-CEA scFv improve the anticancer effect with a less toxic dose of irinotecan
[作者:Uchino, J; Takayama, K; Harada, A; Sone, T; Harada, T; Curiel, DT; Kuroki, M; Nakanishi, Y,期刊:Cancer gene therapy, 页码:94-100 , 文章类型: Article,,卷期:2008年15-2]
- Irinotecan (CPT-11) is a key drug for the treatment of various cancers. CPT-11 can be considered to be a prodrug, since it needs to be activated into the toxic drug SN-38 by the enzyme carboxylesterase. However, CPT-11 m...
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