- An efficient liposomal gene delivery vehicle using Sendai F/HN proteins and protamine
[作者:Kim, HS; Kim, JS; Lee, YK; Koo, KH; Park, YS,期刊:Cancer gene therapy, 页码:214-224 , 文章类型: Article,,卷期:2008年15-4]
- By means of a simple mixing procedure, we have constructed cationic Sendai virosomes consisting of fusogenic viral F/HN proteins and cationic lipids. Sendai virus F/HN proteins were purified by Triton X-100 treatment and...
- Minimally invasive and selective hydrodynamic gene therapy of liver segments in the pig and human
[作者:Khorsandi, SE; Bachellier, P; Weber, JC; Greget, M; Jaeck, D; Zacharoulis, D; Rountas, C; Helmy, S; Helmy, A; Al-Waracky, M; Salama, H; Jiao, L; Nicholls, J; Davies, AJ; Levicar, N; Jensen, S; Habib, N,期刊:Cancer gene therapy, 页码:225-230 , 文章类型: Article,,卷期:2008年15-4]
- This paper highlights our experience of the transfer of hydrodynamic gene therapy (HGT) from the large animal, the pig, into clinical practice. The modification of balloon catheters and the development of a minimally inv...
- Improved lentiviral transduction of human mesenchymal stem cells for therapeutic intervention in pancreatic cancer
[作者:Kallifatidis, G; Beckermann, BM; Groth, A; Schubert, M; Apel, A; Khamidjanov, A; Ryschich, E; Wenger, T; Wagner, W; Diehlmann, A; Saffrich, R; Krause, U; Eckstein, V; Mattern, J; Chai, M; Schutz, G; Ho, AD; Gebhard, MM; Buchler, M; Friess, H; Buchler, P; Herr, I,期刊:Cancer gene therapy, 页码:231-240 , 文章类型: Article,,卷期:2008年15-4]
- Genetic modification of human bone marrow mesenchymal stem cells ( MSC) is highly valuable for their exploitation in basic science and therapeutic applications, for example in cancer. We present here a new, fast and easy...
- Catalase overexpression reduces UVB-induced apoptosis in a human xeroderma pigmentosum reconstructed epidermis
[作者:Rezvani, HR; Ged, C; Bouadjar, B; de Verneuil, H; Taieb, A,期刊:Cancer gene therapy, 页码:241-251 , 文章类型: Article,,卷期:2008年15-4]
- Xeroderma pigmentosum type C (XPC) is a rare autosomal recessive disorder that occurs due to inactivation of the XPC protein, an important DNA damage recognition protein involved in DNA nucleotide excision repair (NER). ...
- Augmented transgene expression in transformed cells using a parvoviral hybrid vector
[作者:Kruger, L; Eskerski, H; Dinsart, C; Cornelis, J; Rommelaere, J; Haberkorn, U; Kleinschmidt, JA,期刊:Cancer gene therapy, 页码:252-267 , 文章类型: Article,,卷期:2008年15-4]
- Autonomous parvoviruses possess an intrinsic oncotropism based on viral genetic elements controlling gene expression and genome replication. We constructed a hybrid vector consisting of the H1 parvovirus-derived expressi...
- Retroviral vectors for clinical immunogene therapy are stable for up to 9 years
[作者:Lamers, CHJ; van Elzakker, P; Luider, BA; van Steenbergen, SCL; Sleijfer, S; Debets, R; Gratama, JW,期刊:Cancer gene therapy, 页码:268-274 , 文章类型: Article,,卷期:2008年15-4]
- Recombinant retroviruses are one of the most commonly used gene transfer vehicles for therapeutic gene delivery. The stability of viral vectors upon long-term storage, anticipated to be short lived, is expected to impact...
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