- The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF
[作者：Behrens, ME; Grandgenett, PM; Bailey, JM; Singh, PK; Yi, CH; Yu, F; Hollingsworth, MA,期刊：Oncogene, 页码：5667-5677 , 文章类型： Article，,卷期：2010年29-42]
- The MUC1 cytoplasmic tail (MUC1.CT) conducts signals from spatial and extracellular cues (growth factor and cytokine stimulation) to evoke a reprogramming of the cellular transcriptional profile. Specific phosphorylated ...
- Cross-talk between PI3K and estrogen in the mouse thyroid predisposes to the development of follicular carcinomas with a higher incidence in females
[作者：Antico-Arciuch, VG; Dima, M; Liao, XH; Refetoff, S; Di Cristofano, A,期刊：Oncogene, 页码：5678-5686 , 文章类型： Article，,卷期：2010年29-42]
- It is well known that thyroid disease is more frequent in women than in men; however, the molecular basis for this gender-based difference is still poorly understood. The activation of phosphoinositide 3-kinase (PI3K), t...
- c-MYC overexpression with loss of Ink4a/Arf transforms bone marrow stromal cells into osteosarcoma accompanied by loss of adipogenesis
[作者：Shimizu, T; Ishikawa, T; Sugihara, E; Kuninaka, S; Miyamoto, T; Mabuchi, Y; Matsuzaki, Y; Tsunoda, T; Miya, F; Morioka, H; Nakayama, R; Kobayashi, E; Toyama, Y; Kawai, A; Ichikawa, H; Hasegawa, T; Okada, S; Ito, T; Ikeda, Y; Suda, T; Saya, H,期刊：Oncogene, 页码：5687-5699 , 文章类型： Article，,卷期：2010年29-42]
- The development of cancer is due to the growth and proliferation of transformed normal cells. Recent evidence suggests that the nature of oncogenic stress and the state of the cell of origin critically affect both tumori...
- Rb inactivation accelerates neoplastic growth and substitutes for recurrent amplification of cIAP1, cIAP2 and Yap1 in sporadic mammary carcinoma associated with p53 deficiency
[作者：Cheng, L; Zhou, Z; Flesken-Nikitin, A; Toshkov, IA; Wang, W; Camps, J; Ried, T; Nikitin, AY,期刊：Oncogene, 页码：5700-5711 , 文章类型： Article，,卷期：2010年29-42]
- Genetically defined mouse models offer an important tool to identify critical secondary genetic alterations with relevance to human cancer pathogenesis. We used newly generated MMTV-Cre105Ayn mice to inactivate p53 and/o...
- Connexin43 inhibits the oncogenic activity of c-Src in C6 glioma cells
[作者：Herrero-Gonzalez, S; Gangoso, E; Giaume, C; Naus, CC; Medina, JM; Tabernero, A,期刊：Oncogene, 页码：5712-5723 , 文章类型： Article，,卷期：2010年29-42]
- One of the characteristics of gliomas is a decrease in the expression of connexin43, a protein that forms gap junctions. Restoring connexin43 expression in glioma cells reduces their exacerbated rate of cell growth, alth...
- Hsa-miR-9 methylation status is associated with cancer development and metastatic recurrence in patients with clear cell renal cell carcinoma
[作者：Hildebrandt, MAT; Gu, J; Lin, J; Ye, Y; Tan, W; Tamboli, P; Wood, CG; Wu, X,期刊：Oncogene, 页码：5724-5728 , 文章类型： Article，,卷期：2010年29-42]
- The long-term prognosis for clear cell renal cell carcinoma (ccRCC) is dramatically altered by the development of metastatic recurrence. However, there are very few indicators that can predict which patient will develop ...
- MUC4 mucin-induced epithelial to mesenchymal transition: a novel mechanism for metastasis of human ovarian cancer cells
[作者：Ponnusamy, MP; Lakshmanan, I; Jain, M; Das, S; Chakraborty, S; Dey, P; Batra, SK,期刊：Oncogene, 页码：5741-5754 , 文章类型： Article，,卷期：2010年29-42]
- The acquisition of invasiveness in ovarian cancer (OC) is accompanied by the process of epithelial-to-mesenchymal transition (EMT). The MUC4 mucin is overexpressed in ovarian tumors and has a role in the invasiveness of ...
- Cell cycle-dependent acetylation of Rb2/p130 in NIH3T3 cells
[作者：Schwarze, F; Meraner, J; Lechner, M; Loidl, A; Stasyk, T; Laich, A; Loidl, P,期刊：Oncogene, 页码：5755-5760 , 文章类型： Article，,卷期：2010年29-42]
- The retinoblastoma protein (pRb) and the pRb-related proteins, p130 and p107, form the 'pocket protein' family of cell cycle regulatory factors. A well characterized function of these proteins is the cell cycle-dependent...
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