- Hypoxia inducible factor-1alpha expression correlates with vascular endothelial growth factor-C expression and lymphangiogenesis/angiogenesis in oral squamous cell carcinoma
[作者:Liang, XH; Yang, DJ; Hu, J; Hao, XM; Gao, JR; Maoi, ZY,期刊:Anticancer Research, 页码:1659-1666 , 文章类型: Article,,卷期:2008年28-3A]
- Background: The number of blood vessels correlates with metastasis in solid tumors, including oral squamous cell carcinoma (OSCC). Hypoxia inducible factor-1alpha (HIF-1 alpha) could play a role in tumor lymphangiogenesi...
- Role of Pur alpha in the modulation of homologous recombination-directed DNA repair by HIV-1 Tat
[作者:Wang, HC; White, MK; Kaminski, R; Darbinian, N; Amini, S; Johnson, EM; Khalili, K; Rappaport, J,期刊:Anticancer Research, 页码:1441-1447 , 文章类型: Article,,卷期:2008年28-3A]
- Background: The nucleic acid-binding protein Pur alpha is involved at stalled DNA replication forks, in double-strand break (DSB) DNA repair and the cellular response to DNA replication stress. Pur alpha interacts with H...
- Invasion front-specific overexpression of tissue inhibitor of metalloproteinase-1 in liver metastases from colorectal cancer
[作者:Kahlert, C; Bandapalli, OR; Schirmacher, P; Weitz, J; Brand, K,期刊:Anticancer Research, 页码:1459-1465 , 文章类型: Article,,卷期:2008年28-3A]
- Background: Matrix metalloproteinases (MMPs) and their inhibitors, the tissue inhibitors of metalloproteinases (TIMPs), have been implicated in invasion and metastasis. The distribution of MMPs and TIMPs in the invasion ...
- IFN-gamma enhances T(H)1 polarisation of monocyte-derived dendritic cells matured with clinical-grade cytokines using serum-free conditions
[作者:Hildenbrand, B; Lorenzen, D; Sauer, B; Hertkorn, C; Freudenberg, MA; Peters, JH; Nesselhut, T; Unger, C; Azemar, M,期刊:Anticancer Research, 页码:1467-1476 , 文章类型: Article,,卷期:2008年28-3A]
- Using serum-free conditions, human monocyte-derived dendritic cells (MoDCs) tend to mature insufficiently in a T(H)1-polarizing direction under approved and standardized clinical conditions. However, for the initiation o...
- 5-fluorouracil-related gene expression in primary sites and hepatic metastases of colorectal carcinomas
[作者:Sameshima, S; Tomozawa, S; Kojima, M; Koketsu, S; Motegi, K; Horikoshi, H; Okada, T; Kon, Y; Sawada, T,期刊:Anticancer Research, 页码:1477-1481 , 文章类型: Article,,卷期:2008年28-3A]
- The aim of this study was to investigate the correlation of the mRNA expressions of 5-fluorouracil (5FU)-related genes in the primary sites and liver metastases of colorectal carcinomas. Patients and Methods: Patients wi...
- A comparison of two orally bioavailable anti-cancer agents, IRC-110160 and STX140
[作者:Foster, PA; Stengel, C; Ali, T; Leese, MP; Potter, BVL; Reed, MJ; Purohit, A; Newman, SP,期刊:Anticancer Research, 页码:1483-1491 , 文章类型: Article,,卷期:2008年28-3A]
- This study characterises two recently developed anticancer agents in vitro and in vivo, 2-methoxyoestra-1,3,5(10), 16-tetraene-3-carboxamide (IRC-110160) and STX140. Materials and Methods: Hormone-dependent (MCF-7), horm...
- Inhibition of steroid sulphatase activity via the percutaneous route: A new option for breast cancer therapy
[作者:Purohit, A; Chander, SK; Woo, LWL; Parsons, MFC; Jhalli, R; Potter, BVL; Reed, MJ,期刊:Anticancer Research, 页码:1517-1523 , 文章类型: Article,,卷期:2008年28-3A]
- Steroid sulphatase (STS) inhibitors have been developed primarily for the treatment of hormone-dependent breast cancer, but may also have utility for the treatment of a number of androgen-dependent skin conditions. STS r...
- Up-regulation of survivin mRNA might be a marker for non-invasive detection of non-small cell lung cancer rather than for prognosis
[作者:Warnecke-Eberz, U; Baldus, SE; Bollschweiler, E; Hoelscher, AH; Metzger, R,期刊:Anticancer Research, 页码:1525-1529 , 文章类型: Article,,卷期:2008年28-3A]
- Background: Survivin suppresses programmed cell death and regulates cell division. To evaluate the prognostic importance of the apoptosis inhibitor survivin for non-small cell lung cancer (NSCLC), a study was performed i...
- The bisphosphonate, zoledronic acid reduces experimental neuroblastoma growth by interfering with tumor angiogenesis
[作者:Backman, U; Svensson, A; Christofferson, RH; Azarbayjani, F,期刊:Anticancer Research, 页码:1551-1557 , 文章类型: Article,,卷期:2008年28-3A]
- Background: Zoledronic acid is a new member of the bisphosphonate (BP) class of compounds, a family of closely related synthetic molecules originally derived from the naturally occurring pyrophosphate. These compounds th...
- Targeting of CDC20 via small interfering RNA causes enhancement of the cytotoxicity of chemoradiation
[作者:Taniguchi, K; Momiyama, N; Ueda, M; Matsuyama, R; Mori, R; Fujii, Y; Ichikawa, Y; Endo, I; Togo, S; Shimada, H,期刊:Anticancer Research, 页码:1559-1563 , 文章类型: Article,,卷期:2008年28-3A]
- Background: Cell division cycle 20 homologue (CDC20), which encodes a protein that promotes chromosomal separation, is highly expressed in several carcinomas, including pancreatic cancer. Materials and Methods: To ascert...
- Flow cytometric phenotype of rhabdomyosarcoma bone marrow metastatic cells and its implication in differential diagnosis with neuroblastoma
[作者:Bozzi, F; Collini, P; Aiello, A; Barzano, E; Gambirasio, F; Podda, M; Meazza, C; Ferrari, A; Luksch, R,期刊:Anticancer Research, 页码:1565-1569 , 文章类型: Article,,卷期:2008年28-3A]
- Background: The goal of this study was to develop a flow cytometric (FCM) method for assessing the presence of metastatic cells in bone marrow (BM) and peripheral blood (PB) obtained from rhabdomysarcoma (RMS) patients. ...
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