- Peripheral Benzodiazepine Receptor ligand-PLGA polymer conjugates potentially useful as delivery systems of apoptotic agents
[作者:Laquintana, V; Denora, N; Musacchio, T; Lasorsa, M; Latrofa, A; Trapani, G,期刊:Journal of controlled release, 页码:185-195 , 文章类型: Article,,卷期:2009年137-39876]
- Poly(D,L-lactic-co-glycolic acid) (PLGA) polymers having different average molecular. weights were chemically conjugated to two imidazopyridinacetamides (1 and 2), chosen as model Peripheral Benzodiazepine Receptor (PBR)...
- Controlled delivery of heat shock protein using an injectable microsphere/hydrogel combination system for the treatment of myocardial infarction
[作者:Lee, J; Tan, CY; Lee, SK; Kim, YH; Lee, KY,期刊:Journal of controlled release, 页码:196-202 , 文章类型: Article,,卷期:2009年137-39876]
- Myocardial infarction causes a high rate of morbidity and mortality worldwide, and heat shock proteins as molecular chaperones have been attractive targets for protecting cardiomyoblasts under environmental stimuli. In t...
- Mucoadhesive effect of thiolated PEG stearate and its modified NLC for ocular drug delivery
[作者:Shen, J; Wang, Y; Ping, QN; Xiao, YY; Huang, X,期刊:Journal of controlled release, 页码:217-223 , 文章类型: Article,,卷期:2009年137-39876]
- This study was to develop a thiolated non-ionic surfactant, cysteine-polyethylene glycol stearate (Cys-PEG-SA), for the assembling of nanoparticulate ocular drug delivery system with mucoadhesive property. Cys-PEG-SA was...
- Effect of siRNA in PEG-coated siRNA-lipoplex on anti-PEG IgM production
[作者:Tagami, T; Nakamura, K; Shimizu, T; Ishida, T; Kiwada, H,期刊:Journal of controlled release, 页码:234-240 , 文章类型: Article,,卷期:2009年137-39876]
- For efficient delivery of small interfering RNA (siRNA) in vivo, it is important to control the blood circulation of the delivery vehicle. Surface modification of the siRNA/cationic liposome complex (siRNA-lipoplex) with...
- Assessment of stability, toxicity and immunogenicity of new polymeric nanoreactors for use in enzyme replacement therapy of MNGIE
[作者:De Vocht, C; Ranquin, A; Willaert, R; Van Ginderachter, JA; Vanhaecke, T; Rogiers, V; Versees, W; Van Gelder, P; Steyaert, J,期刊:Journal of controlled release, 页码:246-254 , 文章类型: Article,,卷期:2009年137-39876]
- The lack of a crucial metabolic enzyme can lead to accumulating substrate concentrations in the bloodstream and severe human enzyme deficiency diseases. Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE) is su...
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