- Second-generation high-throughput forward genetic screen in mice to isolate subtle behavioral mutants
[作者:Kumar, V; Kim, K; Joseph, C; Thomas, LC; Hong, H; Takahashi, JS,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:15557-15564 , 文章类型: Article,,卷期:2011年108-Suppl.3]
- Forward genetic screens have been highly successful in revealing roles of genes and pathways in complex biological events. Traditionally these screens have focused on isolating mutants with the greatest phenotypic devian...
- Quantifying the buildup in extent and complexity of free exploration in mice
[作者:Benjamini, Y; Fonio, E; Galili, T; Havkin, GZ; Golani, I,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:15580-15587 , 文章类型: Article,,卷期:2011年108-Suppl.3]
- To obtain a perspective on an animal's own functional world, we study its behavior in situations that allow the animal to regulate the growth rate of its behavior and provide us with the opportunity to quantify its momen...
- Sex difference in the near-24-hour intrinsic period of the human circadian timing system
[作者:Duffy, JF; Cain, SW; Chang, AM; Phillips, AJK; Munch, MY; Gronfier, C; Wyatt, JK; Dijk, DJ; Wright, KP; Czeisler, CA,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:15602-15608 , 文章类型: Article,,卷期:2011年108-Suppl.3]
- The circadian rhythms of melatonin and body temperature are set to an earlier hour in women than in men, even when the women and men maintain nearly identical and consistent bedtimes and wake times. Moreover, women tend ...
- Quantitative descriptions of generalized arousal, an elementary function of the vertebrate brain
[作者:Quinkert, AW; Vimal, V; Weil, ZM; Reeke, GN; Schiff, ND; Banavar, JR; Pfaff, DW,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:15617-15623 , 文章类型: Article,,卷期:2011年108-Suppl.3]
- We review a concept of the most primitive, fundamental function of the vertebrate CNS, generalized arousal (GA). Three independent lines of evidence indicate the existence of GA: statistical, genetic, and mechanistic. He...
- Architecture, constraints, and behavior
[作者:Doyle, JC; Csete, M,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:15624-15630 , 文章类型: Article,,卷期:2011年108-Suppl.3]
- This paper aims to bridge progress in neuroscience involving sophisticated quantitative analysis of behavior, including the use of robust control, with other relevant conceptual and theoretical frameworks from systems en...
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