- Fine-mapping the gene for X-linked myopathy with excessive autophagy
[作者:Munteanu, I; Ramachandran, N; Mnatzakanian, GN; Villanova, M; Fardeau, M; Levy, N; Kissel, JT; Minassian, BA,期刊:Neurology, 页码:951-953 , 文章类型: Article,,卷期:2008年71-12]
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- Burden of atherosclerosis and risk of venous thromboembolism in patients with migraine
[作者:Schwaiger, J; Kiechl, S; Stockner, H; Knoflach, M; Werner, P; Rungger, G; Gasperi, A; Willeit, J,期刊:Neurology, 页码:937-943 , 文章类型: Article,,卷期:2008年71-12]
- Background: Previous studies have yielded evidence of an enhanced risk of cardiovascular disease, especially stroke, among patients with migraine. Our understanding of the underlying mechanisms is far from complete. The ...
- Natural history of young-adult amyotrophic lateral sclerosis
[作者:Sabatelli, M; Madia, F; Conte, A; Luigetti, M; Zollino, M; Mancuso, I; Lo Monaco, M; Lippi, G; Tonali, P,期刊:Neurology, 页码:876-881 , 文章类型: Article,,卷期:2008年71-12]
- Background: Amyotrophic lateral sclerosis (ALS) affects people of all ages, but whether the wide range of age at onset is due to distinct diseases or merely reflects phenotypic variability of the same disorder is still u...
- Onset of terminal decline in cognitive abilities in individuals without dementia
[作者:Thorvaldsson, V; Hofer, SM; Berg, S; Skoog, I; Sacuiu, S; Johansson, B,期刊:Neurology, 页码:882-887 , 文章类型: Article,,卷期:2008年71-12]
- Objective: To identify time of onset and rate of mortality-related change (terminal decline) in cognitive abilities in later life.Method: The sample consisted of 288 individuals without dementia (born 1901-1902) drawn fr...
- Imaging amyloid deposition in Lewy body diseases
[作者:Gomperts, SN; Rentz, DM; Moran, E; Becker, JA; Locascio, JJ; Klunk, WE; Mathis, CA; Elmaleh, DR; Shoup, T; Fischman, AJ; Hyman, BT; Growdon, JH; Johnson, KA,期刊:Neurology, 页码:903-910 , 文章类型: Article,,卷期:2008年71-12]
- Background: Extrapyramidal motor symptoms precede dementia in Parkinson disease (PDD) by many years, whereas dementia occurs early in dementia with Lewy bodies (DLB). Despite this clinical distinction, the neuropsycholog...
- Detecting navigational deficits in cognitive aging and Alzheimer disease using virtual reality
[作者:Cushman, LA; Stein, K; Duffy, CJ,期刊:Neurology, 页码:888-895 , 文章类型: Article,,卷期:2008年71-12]
- Background: Older adults get lost, in many cases because of recognized or incipient Alzheimer disease (AD). In either case, getting lost can be a threat to individual and public safety, as well as to personal autonomy an...
- T2 relaxometry and fMRI of the brain in late-onset restless legs syndrome
[作者:Astrakas, LG; Konitsiotis, S; Margariti, P; Tsouli, S; Tzarouhi, L; Argyropoulou, MI,期刊:Neurology, 页码:911-916 , 文章类型: Article,,卷期:2008年71-12]
- Objective: To assess in patients with late-onset idiopathic restless legs syndrome (RLS) the brain iron content with magnetic resonance relaxometry, and brain activation during dorsiflexion and plantar flexion of both fe...
- CTLA4Ig treatment in patients with multiple sclerosis - An open-label, phase 1 clinical trial
[作者:Viglietta, V; Bourcier, K; Buckle, GJ; Healy, B; Weiner, HL; Hafler, DA; Egorova, S; Guttmann, CRG; Rusche, JR; Khoury, SJ,期刊:Neurology, 页码:917-924 , 文章类型: Article,,卷期:2008年71-12]
- Background: The modulation of costimulatory pathways represents an original therapeutic approach to regulate T cell-mediated autoimmune diseases by preventing or reducing autoantigen-driven T-cell activation in humans. A...
- PINK1 mutations and parkinsonism
[作者:Ishihara-Paul, L; Hulihan, MM; Kachergus, J; Upmanyu, R; Warren, L; Amouri, R; Elango, R; Prinjha, RK; Soto, A; Kefi, M; Zouari, M; Sassi, SB; Yahmed, SB; El Euch-Fayeche, G; Matthews, PM; Middleton, LT; Gibson, RA; Hentati, F; Farrer, MJ,期刊:Neurology, 页码:896-902 , 文章类型: Article,,卷期:2008年71-12]
- Background: PINK1 loss-of-function causes recessive, early-onset parkinsonism. In Tunisia there is a high rate of consanguineous marriage but PINK1 carrier frequency and disease prevalence have yet to be assessed.Objecti...
- Insights into the dynamics of hereditary diffuse leukoencephalopathy with axonal spheroids
[作者:Van Gerpen, JA; Wider, C; Broderick, DF; Dickson, DW; Brown, LA; Wszolek, ZK,期刊:Neurology, 页码:925-929 , 文章类型: Article,,卷期:2008年71-12]
- Objective: To report a new American family with hereditary diffuse leukoencephalopathy with spheroids (HDLS), including serial, presymptomatic and symptomatic, cranial MRIs from the proband.Methods: We report clinical an...
- Neuronal surface antigen antibodies in limbic encephalitis - Clinical-immunologic associations
[作者:Graus, F; Saiz, A; Lai, M; Bruna, J; Lopez, F; Sabater, L; Blanco, Y; Rey, MJ; Ribalta, T; Dalmau, J,期刊:Neurology, 页码:930-936 , 文章类型: Article,,卷期:2008年71-12]
- Objective: To report the frequency and type of antibodies against neuronal surface antigens (NSA-ab) in limbic encephalitis (LE).Methods: Analysis of clinical features, neuropathologic findings, and detection of NSA-ab u...
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