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  • Natural history of young-adult amyotrophic lateral sclerosis
    [作者:Sabatelli, M; Madia, F; Conte, A; Luigetti, M; Zollino, M; Mancuso, I; Lo Monaco, M; Lippi, G; Tonali, P,期刊:Neurology, 页码:876-881 , 文章类型: Article,,卷期:2008年71-12]
  • Background: Amyotrophic lateral sclerosis (ALS) affects people of all ages, but whether the wide range of age at onset is due to distinct diseases or merely reflects phenotypic variability of the same disorder is still u...
  • Imaging amyloid deposition in Lewy body diseases
    [作者:Gomperts, SN; Rentz, DM; Moran, E; Becker, JA; Locascio, JJ; Klunk, WE; Mathis, CA; Elmaleh, DR; Shoup, T; Fischman, AJ; Hyman, BT; Growdon, JH; Johnson, KA,期刊:Neurology, 页码:903-910 , 文章类型: Article,,卷期:2008年71-12]
  • Background: Extrapyramidal motor symptoms precede dementia in Parkinson disease (PDD) by many years, whereas dementia occurs early in dementia with Lewy bodies (DLB). Despite this clinical distinction, the neuropsycholog...
  • T2 relaxometry and fMRI of the brain in late-onset restless legs syndrome
    [作者:Astrakas, LG; Konitsiotis, S; Margariti, P; Tsouli, S; Tzarouhi, L; Argyropoulou, MI,期刊:Neurology, 页码:911-916 , 文章类型: Article,,卷期:2008年71-12]
  • Objective: To assess in patients with late-onset idiopathic restless legs syndrome (RLS) the brain iron content with magnetic resonance relaxometry, and brain activation during dorsiflexion and plantar flexion of both fe...
  • PINK1 mutations and parkinsonism
    [作者:Ishihara-Paul, L; Hulihan, MM; Kachergus, J; Upmanyu, R; Warren, L; Amouri, R; Elango, R; Prinjha, RK; Soto, A; Kefi, M; Zouari, M; Sassi, SB; Yahmed, SB; El Euch-Fayeche, G; Matthews, PM; Middleton, LT; Gibson, RA; Hentati, F; Farrer, MJ,期刊:Neurology, 页码:896-902 , 文章类型: Article,,卷期:2008年71-12]
  • Background: PINK1 loss-of-function causes recessive, early-onset parkinsonism. In Tunisia there is a high rate of consanguineous marriage but PINK1 carrier frequency and disease prevalence have yet to be assessed.Objecti...