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  • Progranulin variability has no major role in Parkinson disease genetic etiology
    [作者:Nuytemans, K; Pals, P; Sleegers, K; Engelborghs, S; Corsmit, E; Peeters, K; Pickut, B; Mattheijssens, M; Cras, P; De Deyn, PP; Theuns, J; Van Broeckhoven, C,期刊:Neurology, 页码:1147-1151 , 文章类型: Article,,卷期:2008年71-15]
  • Background: Different loss-of-function mutations were identified underlying PGRN haploinsufficiency in patients with frontotemporal lobar degeneration. PGRN mutations were also identified in other neurodegenerative brain...
  • Dose comparison trial of sustained-release fampridine in multiple sclerosis
    [作者:Goodman, AD; Brown, TR; Cohen, JA; Krupp, LB; Schapiro, R; Schwid, SR; Cohen, R; Marinucci, LN; Blight, AR,期刊:Neurology, 页码:1134-1141 , 文章类型: Article,,卷期:2008年71-15]
  • Objective: To examine the efficacy and safety of three different doses of sustained- release fampridine in people with multiple sclerosis (MS).Method: This multicenter, randomized, double-blind, placebo-controlled, paral...